Frontiers | KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization ORIGINAL RESEARCH article Front. Immunol. , 11 December 2018 Sec. Microbial Immunology Volume 9 - 2018 | Published in Frontiers in Immunolog…
Abstract Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics. This identified viral…
…uired for epidermal differentiation. Epigenetic regulation by histone modifying proteins and noncoding RNA In addition to classical gene regulatory networks noted above, we have recently identified a central role for additional biologic mechanisms, namely gene regulation by chrom…
…science and biomedical applications. Dr. Cochran's translational interests span protein-based drug discovery and development for applications in oncology and regenerative medicine, and the development of new technologies for high-throughput protein analysis and engineering. Dr. C…
…II and PSI) in spaceflight, with the plant shifting photosystem core-regulatory proteins in an organ-specific manner to adapt to the microgravity environment. An overview of the ribosome, spliceosome, and proteasome activities in spaceflight revealed a significant abundance of tr…
Abstract The human protein tyrosine phosphatase TCPTP exists as two forms: an endoplasmic reticulum-targeted 48-kDa form (TC48) and a nuclear 45-kDa form (TC45). Although targeted to the nucleus, TC45 can exit in response to specific stimuli to dephosphorylate cytoplasmic substra…
…driven the evolution and maintenance of this polymorphism [8] Merozoite surface protein 1 (MSP-1) is the most abundant surface component of the merozoite stage of the parasite life cycle, making up 40% of the GPI-anchored merozoite surface protein coat [12] [13] [14] . MSP-1 is a…
…524. View in: PubMed Mentions: Fields: Translation: Humans Animals Translocator protein (TSPO), still an enigmatic transmembrane protein: From structures to functions. Biochimie. 2024 Sep; 224:1-2. Lacapere JJ, Papadopoulos V . PMID: 39067561. View in: PubMed Mentions: Fields: Tr…
Protein tyrosine phosphatase 1B in metabolic and cardiovascular diseases: from mechanisms to therapeutics - PMC Official websites use .gov .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS lock ) or means you've safel…
Differences in Oligomerization of the SARS-CoV-2 Envelope Protein, Poliovirus VP4, and HIV Vpu. Biochemistry. 2024 02 06; 63(3):241-250. Townsend JA, Fapohunda O, Wang Z, Pham H, Taylor MT, Kloss B, Park SH, Opella S , Aspinwall CA, Marty MT. PMID: 38216552; PMCID: PMC10872257 . …
…10312804 . View in: PubMed Mentions: 1 Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee. Amyloid. 2024 Dec; 31(4):249-256. Buxbaum JN, Eisenberg DS , Fändrich M, McPhail ED, Merlini G, …
PARylation of the forkhead‐associated domain protein DAWDLE regulates plant immunity | EMBO Reports | Springer Nature Link Advertisement EMBO Press journals have moved to Springer Nature Link. Learn more about website changes. PARylation of the forkhead‐associated domain protein …
10 high-protein foods: Which are healthy and which aren’t? By Lindsay Moyer, MS, RDN Updated: February 5, 2026 NIQ Product Explorer (Fairlife), Lindsay Moyer - CSPI (Kodiak), Marlena Koch - CSPI (all others). “We are ending the war on protein,” announced the new Dietary Guideline…
Frontiers | Protein tyrosine phosphatase 1B in metabolic and cardiovascular diseases: from mechanisms to therapeutics REVIEW article Front. Cardiovasc. Med. , 22 August 2024 Sec. Cardiovascular Metabolism Volume 11 - 2024 | Published in Frontiers in Cardiovascular Medicine Cardio…
Abstract Glial fibrillary acidic protein (GFAP) is an intermediate filament structural protein involved in cytoskeleton assembly and integrity, expressed in high abundance in activated glial cells. GFAP is neuroprotective, as knockout mice are hypersensitive to traumatic brain in…