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Cochrane
Research Services
London, England
70,262 followers
Trusted evidence.
Informed decisions.
Better health.
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Cochrane is a global, independent, non-profit network of health researchers and professionals, patients and carers who work together to produce and promote trusted, high-quality health information that improves health and healthcare worldwide.

Cochrane is for anyone interested in using high-quality information to make health decisions. Whether you are a doctor or nurse, patient or carer, researcher or funder, Cochrane evidence provides a powerful tool to enhance your healthcare knowledge and decision making.

Our members and supporters come from more than 130 countries, worldwide. Our volunteers and contributors are researchers, health professionals, patients, carers, and people passionate about improving health outcomes for everyone, everywhere. Our global independent network gathers and summarizes the best evidence from research to help you make informed choices about treatment and we have been doing this for 30 years.

We do not accept commercial or conflicted funding. This is vital for us to generate authoritative and reliable information, working freely, unconstrained by commercial and financial interests.
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Research Services
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51-200 employees
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London, England
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Founded
1993
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Cochrane
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🌍️ 💉 It's World Immunization Week, and this week, we take a look at the safety and effectiveness of the HPV vaccine.

Cervical cancer is preventable, yet it still claims more than 300,000 lives a year and is the 4th most common cancer in women worldwide.

A Cochrane review examined all the evidence from 225 studies, including data from over 132 million patients.

It found that if you vaccinate before age 16, there is an 80% decrease in cervical cancer, and there are only minor, short-term side effects, such as a sore arm at the vaccination site.

This vaccine isn't exclusively for the benefit of women and young girls, as HPV can also cause cancers in men.

Since the programme has been expanded to start including boys under 16 in some countries, it has the potential to save even more lives in the future.
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Cochrane
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1d
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We have introduced a new feature to make retracted articles in CENTRAL easier to identify at a glance.

Search results and record pages now display a clear, prominent retraction label for all CENTRAL articles we know have been retracted by the publisher.

This will help you quickly recognize when reports of randomized controlled trials may no longer be trustworthy, supporting our mission to be the home of trustworthy evidence.

Find out more:
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Cochrane
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2d
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This World Earth Day, we’re thinking about the role evidence can play in a healthier and more sustainable future.

At Cochrane, we’re proud to be contributing to the DESTINY project, a collaborative initiative focused on building the next generation of evidence synthesis tools driven by artificial intelligence to deliver rigorous living evidence in climate and health that matters to policymakers and other evidence users.

🔗 Learn more about the DESTINY project:
#WorldEarthDay
#EarthDay
#EvidenceBasedPolicy
#Sustainability
#ClimateAction
#Cochrane
#DESTINYProject
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Cochrane
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3d
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🌐 Want to learn more about evidence-based decision making in healthcare?

Join Fabio Di Bello to discover best practices and how to apply Cochrane Library evidence to your work.

Register now for the free webinar (and certificate) →
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Cochrane
70,262 followers
4d
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With the 2026 Cochrane Colloquium fast approaching, we take a look back at some of the inspiring speakers from the 2023 Cochrane Colloquium in London.

The Cochrane Lecture / Closing Plenary was delivered by Yemisi Takwoingi, Professor of Test Evaluation and Evidence Synthesis at the
University of Birmingham
. Professor Takwoingi delivered a lecture that explored a framework for sustaining and promoting trusted evidence that not only withstands scrutiny but actively guides informed decision-making by addressing emerging needs through a continuous feedback loop between evidence producers and users.

Keep an eye out for who will be speaking at our next Colloquium in Krakow, Poland!
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Cochrane
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1w
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We have released a pre-print of the protocol for our innovative study that will test whether artificial intelligence tools can support or enhance evidence synthesis.

How does the study work? And what makes it novel?

Take a look at our latest blog where
Gerald Gartlehner
from
Cochrane Austria
, who is Principal Investigator for the study, answers these questions:
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Cochrane
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1w
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Anti-amyloid drugs likely show no clinically meaningful benefit, according to a new Cochrane review of 17 trials and over 20,000 participants.

Designed to clear the buildups of amyloid beta protein that are linked to Alzheimer's, early trials of these drugs showed statistically significant results. However, these did not translate into a meaningful difference for patients' cognition or daily life.

In addition to the absence of clinically meaningful effects, the review found that anti-amyloid drugs likely increase the risk of swelling and bleeding in the brain.

“There is now a convincing body of evidence converging on the conclusion that there is no clinically meaningful effect," said lead author Francesco Nonino, neurologist and epidemiologist at
IRCCS Istituto delle Scienze Neurologiche di Bologna

Read more:
IRCCS Istituto delle Scienze Neurologiche di Bologna
Radboudumc
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Cochrane
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Join us on 28 May for the webinar An Introduction to Cochrane Clinical Answers (CCAs) and explore how CCAs can support healthcare professionals with clear, actionable evidence.

In this session, you will learn what CCAs are, how they are developed, and who contributes to creating them. We will also show you how to find, navigate, cite, and apply CCAs effectively in clinical practice.

A live demonstration will showcase key features, including the new Clinical Interpretations feature, which offers a clear, practical takeaway for each clinical question.

This webinar is open to healthcare professionals, students, trainees, librarians, administrative staff, and anyone in the wider Cochrane community who wants to make better use of trusted evidence.
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Cochrane
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1w
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🏃♀️ Can running shoes prevent lower-limb injuries in adults? 🏃♂️

A Cochrane review looked at whether different types of running shoes can help prevent lower‑limb injuries in adult runners. The review included 12 studies with 11,240 participants. These studies ran from 6 to 26 weeks and took place in North America, Europe, Australia, and South Africa.

Running shoes are made with features intended to limit foot movement or reduce the forces on the body, with the aim of lowering the risk of injury. However, there is uncertainty around how effective running shows are for preventing injury.

Here is what we found:

👟Neutral/cushioned shoes may make little or no difference to injuries compared to minimalist shoes (low‐certainty evidence)

👟It is uncertain if motion control shoes reduce lower‐limb injuries compared with neutral/cushioned shoes

👟Soft midsole shoes may make little or no difference compared with hard midsole shoes (low‐certainty evidence)

👟It’s uncertain if stability shoes reduce injury compared with neutral/cushioned shoes

👟It is uncertain whether or not motion control shoes reduce injury compared with stability shoes

👟Prescribing running shoes and selecting on foot posture probably makes little or no difference (moderate‐certainty evidence)

There is no strong evidence that choosing a particular kind of running shoe will help you avoid injury. More high‑quality research is needed.

Read more about it here👉️
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Karla Soares-Weiser
1w
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I was pleased to speak this morning on day one of the East Africa Stakeholder Engagement Meeting on Evidence‑Informed Decision Making, alongside
Cochrane Kenya
and the Director General of
Kenya Medical Research Institute (KEMRI)

This meeting is aiming to map the current evidence ecosystem in East Africa, align regional priorities with global initiatives such as the Evidence Synthesis Infrastructure Collaborative, and co‑develop a practical, regional plan for strengthening evidence‑informed decision making. Most importantly, it is focused on strengthening collaboration between those who fund evidence, those who produce it and those who use it to make decisions.

We need an ecosystem where evidence is generated in response to real needs, shared in ways that are usable, and applied in decisions that make a difference — in ministries, in health services, and in communities. Achieving this calls for collaboration at a different level. Strong evidence systems cannot be built for regions. They need to be built with regions, and led by them.

That is why this convening is so encouraging. It reflects regional leadership in action. It is about East Africa defining its own priorities, building its own partnerships, and shaping how it connects to global efforts.

I look forward to hearing about the partnerships, ideas and outcomes that will emerge from these discussions.
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