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Evaluating Viral Load Sampling Schemes and Swabbing Methods for Optimal Surrogacy. J Infect Dis. 2026 Feb 18; 233(2):e585-e586. Mateja A, Chu E, Murray TA, Bramante CT, Moser C, Givens N, Abdelghany M, Blair C, Chen S, Lat PK, Harari O, Kallewaard NL, Macpherson LF, Boulware DR, Suñer C, Mitjà O, Adam SJ, De Gruttola V, Hughes MD, Rubin D, Smith DM, Potter GE. PMID: 40832932.
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Impact of COVID-19 Monoclonal Antibody Therapy on Subsequent Vaccine-elicited SARS-CoV-2 Immune Responses. J Infect Dis. 2026 Feb 17. Smith D, Weir IR, Ramirez S, Coelho CH, Manne-Goehler J, Aziz M, Benson CA, Wu X, Hyer R, Dhillon PK, Faraji F, Bloom N, Myers A, Ramezani-Rad P, Lopez PG, Parikh UM, Heaps AL, Javan AC, Bender Ignacio RA, Li JZ, Greninger AL, Daar ES, Wohl DA, Crotty S, Sieg SF, Chew KW. PMID: 41700320.
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When the Money Stops: A Safety-First Plan for Paused Clinical Trials. Clin Transl Sci. 2026 Jan; 19(1):e70465. Smith D. PMID: 41451898; PMCID: PMC12741915.
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Fast standard error estimation for joint models of longitudinal and time-to-event data based on stochastic EM algorithms. Biostatistics. 2025 12 31; 26(1). Yu T, Wu L, Bosch RJ, Smith DM, Wang R. PMID: 39523821; PMCID: PMC11823262.
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An iPSC-derived model for drug screening in cerebral small vessel disease. J Cereb Blood Flow Metab. 2025 Nov 07; 271678X251389379. Granata A, Al-Thani M, Goodwin-Trotman M, Smith DM, Van Agtmael T, Markus HS. PMID: 41200916; PMCID: PMC12597805.
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Relationship Between Opioid Use, Depression, and Quality of Life Among Persons With HIV at End of Life. J Acquir Immune Defic Syndr. 2025 Nov 01; 100(3):e8-e11. Higgins N, Patel N, Solso S, Dullano C, Riggs PK, Hastie E, Taylor J, Kaytes A, Deiss R, Smith D, Gianella S, Chaillon A, Dubé K. PMID: 40757930; PMCID: PMC12374249.
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HIV Reservoir Dynamics and Bacteriome Composition Along the Gut Axis. J Infect Dis. 2025 Oct 29. Trunfio M, Smith D, Gaitan N, Awad M, Porrachia M, Wells A, Rivera-Nieves J, Hastie E, Riggs P, Gianella S, Chaillon A. PMID: 41162327.
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The Choice of Viral Load End Point in Early Phase Trials of COVID-19 Treatments Aiming to Reduce 28-Day Hospitalization and/or Death. J Infect Dis. 2025 Jul 30; 232(1):60-68. Mateja A, Chu E, Murray TA, Bramante CT, Moser C, Givens N, Abdelghany M, Blair C, Chen S, Lat PK, Harari O, Kallewaard NL, Macpherson LF, Boulware DR, Suñer C, Mitjà O, Adam SJ, De Gruttola V, Hughes MD, Rubin D, Smith DM, Potter GE. PMID: 40461945; PMCID: PMC12308656.
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Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR, Phase 3, Randomized, Double-blind, Placebo-Controlled Trial. Clin Infect Dis. 2025 Jul 18; 80(6):1235-1244. Luetkemeyer AF, Chew KW, Lacey S, Hughes MD, Harrison LJ, Daar ES, Eron J, Fletcher CV, Greninger AL, Hessinger D, Li JZ, Mailhot D, Wohl D, Chayakulkeeree M, Mendoza JLA, Elistratova P, Makinde O, Morgan G, Portsmouth S, Uehara T, Smith D, Currier JS. PMID: 39960062; PMCID: PMC12272848.
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Salvaging information from paused or stopped clinical studies. Clin Trials. 2025 Dec; 22(6):761-762. Smith D, Fleming T, Gianella S, Halloran E, Hillier S, Longini I, Smeaton L, DeGruttola V. PMID: 40650496; PMCID: PMC12331140.
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Vaccine hesitancy and economic hardship: A latent class analysis of racial and ethnic minority communities at high risk of COVID-19 infection in Southern California. Hum Vaccin Immunother. 2025 Dec; 21(1):2529612. Skaathun B, I Rodríguez-Rosales C, Gahbler-Lopez G, R Furtwengler S, Salgin L, A Muñoz F, M Smith D, K Stockman J, O'Bryan SE, Ramirez D, James-Price C, E Servin A. PMID: 40637161; PMCID: PMC12247110.
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Concerns About Crisis Pregnancy Centers Analysis-Reply. JAMA Intern Med. 2025 Jul 01; 185(7):903-904. Desai KS, Smith DM, Ayers JW. PMID: 40354081.
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Discovery and Validation of a Novel Class of Necroptosis Inhibitors Targeting RIPK1. ACS Chem Biol. 2025 Jul 18; 20(7):1527-1543. Soday L, Seripracharat C, Gray JL, Luz AFS, Howard RT, Singh R, Burden TJ, Bernardini E, Mateus-Pinheiro M, Petersen J, Gunnarsson A, Gunnarsson J, Aagaard A, Sjögren T, Maslen S, Bartlett EJ, Iles AF, Smith DM, Scott JS, Skehel M, Davis AM, Ressurreição AS, Moreira R, Rodrigues CMP, Shenoy AR, Tate EW. PMID: 40539767; PMCID: PMC12281487.
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Viral and Immune Risk Factors of HIV Rebound After Interruption of Antiretroviral Therapy. J Infect Dis. 2025 Jun 02; 231(5):1221-1229. Gianella S, Yu T, Wang R, Ignacio C, Schanz M, Kouyos RD, Caballero G, Gaitan NC, Rawlings S, Kuster H, Metzner KJ, Gandhi RT, Li JZ, Günthard HF, Smith DM, Chaillon A. PMID: 39661441; PMCID: PMC12128076.
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Occupancy of the HbYX hydrophobic pocket is sufficient to induce gate opening in the archaeal 20S proteasomes. bioRxiv. 2025 May 29. Chuah JJY, Daugherty MR, Smith DM. PMID: 38826226; PMCID: PMC11142061.
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Immunomodulation by AZD1656 reverses cardiac dysfunction, metabolic remodelling and reduces infarct size in type 2 diabetic cardiomyopathy. bioRxiv. 2025 Apr 11. Anderson S, Karlstaedt A, Chen J, O'Riordan CE, Barnes MR, Štaka Z, Albee LJ, Garrod-Ketchley C, Dambure Vithanachchi ST, Prag HA, Cvetko F, Thiemermann C, Lewis AJ, Murphy MP, Smith DM, Henson SM, Tyler DJ, Aksentijevic D. PMID: 40291746; PMCID: PMC12027331.
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Implementation and impact of a diversity supplement repository. J Clin Transl Sci. 2025; 9(1):e85. Gholami M, Kintzer E, Wong M, Smith D, Depp C. PMID: 40384750; PMCID: PMC12083204.
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Hyperactive 20S Proteasome Enhances Proteostasis and ERAD in C. elegans via degradation of Intrinsically Disordered Proteins. bioRxiv. 2025 Apr 09. Salcedo-Tacuma D, Asad N, Anderson R, Smith DM. PMID: 38617285; PMCID: PMC11014606.
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Growing Health Concern Regarding Gambling Addiction in the Age of Sportsbooks. JAMA Intern Med. 2025 Apr 01; 185(4):382-389. Yeola A, Allen MR, Desai N, Poliak A, Yang KH, Smith DM, Ayers JW. PMID: 39960737; PMCID: PMC11833657.
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Implementation of a seamless phase 2/3 study design in the setting of an emergent infectious disease pandemic: Lessons learned from the ACTIV-2 platform COVID-19 treatment trial. Contemp Clin Trials. 2025 Jun; 153:107887. Giganti MJ, Chew KW, Moser C, Eron JJ, Pinilla M, Li JZ, Ritz J, Javan AC, Wohl DA, Daar ES, Currier JS, Smith DM, Hughes MD, ACTIV-2/A5401 Study Team. PMID: 40147543; PMCID: PMC12085286.
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Publisher Correction: The glucose transporter 2 regulates CD8+ T cell function via environment sensing. Nat Metab. 2025 Mar; 7(3):634. Fu H, Vuononvirta J, Fanti S, Bonacina F, D'Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi MP, Grevitt P, Sheikh MH, Solito E, Godinho SA, Bombardieri M, Smith DM, Cooper D, Iqbal AJ, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD, Marelli-Berg FM. PMID: 40000839; PMCID: PMC11946881.
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Early Viral Dynamics Predict Human Immunodeficiency Virus Posttreatment Control After Analytic Treatment Interruption. J Infect Dis. 2025 Feb 20; 231(2):e419-e428. Magombedze G, Vendrame E, SenGupta D, Geleziunas R, Little S, Smith D, Walker B, Routy JP, Hecht FM, Chun TW, Sneller M, Li JZ, Deeks SG, Peluso MJ. PMID: 39513745; PMCID: PMC11841646.
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Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2025 02 18; 333(7):609-628. Gandhi RT, Landovitz RJ, Sax PE, Smith DM, Springer SA, Günthard HF, Thompson MA, Bedimo RJ, Benson CA, Buchbinder SP, Crabtree-Ramirez BE, Del Rio C, Eaton EF, Eron JJ, Hoy JF, Lehmann C, Molina JM, Jacobsen DM, Saag MS. PMID: 39616604.
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Tixagevimab/cilgavimab or placebo for COVID-19 in ACTIV-2: Safety, pharmacokinetics and neutralizing and anti-drug antibodies. iScience. 2025 Mar 21; 28(3):111938. Bender Ignacio RA, Chew KW, Moser C, Currier JS, Eron JJ, Javan AC, Giganti MJ, Ritz J, Gibbs M, Kouekam HT, Esser MT, Daar ES, Choudhary M, Deo R, Fletcher CV, Li JZ, Hughes MD, Smith D, Wohl DA, ACTIV-2/A5401 Study Team. PMID: 40124489; PMCID: PMC11927737.
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Chronic conditions, COVID-19 vaccination, and institutional trust among Hispanic/Latinx communities in San Diego, California. Prev Med. 2025 Mar; 192:108240. Streuli S, Servin AE, Salgin L, Muñoz FA, Smith DM, Stockman JK, O'Bryan SE, Ramirez D, James-Price C, Skaathun B. PMID: 39909210.
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Characterizing Services Advertised on Crisis Pregnancy Center Websites. JAMA Intern Med. 2025 Feb 01; 185(2):238-240. Desai KS, Keene H, Dredze M, Smith DM, Ayers JW. PMID: 39621321; PMCID: PMC11612908.
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Sexual Networks and Behavioral Characteristics of HIV-Positive Male Military Members, Female Sex Workers, and Male Civilians. AIDS Behav. 2025 Mar; 29(3):993-1003. Grillo MP, Saylors K, Tran BR, Brown N, Tripathi O, Killion J, Macera C, Faye B, Chisoko EC, Kabengele M, Mutombe AM, Djoko CF, Smith D, Chaillon A. PMID: 39806186; PMCID: PMC11830637.
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Inpatient service utilization amongst infants diagnosed with Respiratory Syncytial Virus infection (RSV) in the United States. PLoS One. 2025; 20(1):e0317367. Gantenberg JR, Thompson KD, van Aalst R, Smith DM, Richards M, Nelson CB, La Via WV, Chaves SS, Bengtson AM, Savitz DA, Zullo AR. PMID: 39804848; PMCID: PMC11730397.
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Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors. Cell Rep. 2025 01 28; 44(1):115202. George AF, Neidleman J, Luo X, Frouard J, Elphick N, Yin K, Young KC, Ma T, Andrew AK, Ezeonwumelu IJ, Pedersen JG, Chaillon A, Porrachia M, Woodworth B, Jakobsen MR, Thomas R, Smith DM, Gianella S, Roan NR. PMID: 39798087; PMCID: PMC11829653.
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Early antiviral CD4+ and CD8+ T cells are associated with upper airway clearance of SARS-CoV-2. JCI Insight. 2024 Dec 20; 9(24). Ramirez SI, Lopez PG, Faraji F, Parikh UM, Heaps A, Ritz J, Moser C, Eron JJ, Wohl D, Currier J, Daar ES, Greninger A, Klekotka P, Grifoni A, Weiskopf D, Sette A, Peters B, Hughes MD, Chew KW, Smith DM, Crotty S, Accelerating COVID-19 Therapeutic Interventions and Vaccines-2 (ACTIV-2)/A5401 Study Team. PMID: 39704169; PMCID: PMC11665554.
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Quality of Life in People With HIV at the End of Life: Preliminary Results From the Last Gift Observational Cohort Study. J Acquir Immune Defic Syndr. 2025 01 01; 98(1):82-89. Coler B, Honerkamp Smith G, Arora AK, Wells A, Solso S, Dullano C, Concha-Garcia S, Hill E, Riggs PK, Korolkova A, Deiss R, Smith D, Sundermann EE, Gianella S, Chaillon A, Dubé K. PMID: 39361015; PMCID: PMC11623374.
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High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS. SLAS Discov. 2024 12; 29(8):100197. Ismail M, Davies G, Sproat G, Monteverde T, Tart J, Acebrón-García-de-Eulate M, Gohlke A, Hancock D, Adhikari S, Stefanovic-Barrett S, Smith DM, Flemington V, Gleave-Hanford ES, Holdgate GA, Kettle JG, Downward J. PMID: 39613028.
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SARS-CoV-2 Monoclonal Antibody Treatment Followed by Vaccination Shifts Human Memory B-Cell Epitope Recognition, Suggesting Antibody Feedback. J Infect Dis. 2024 Nov 15; 230(5):1187-1196. Bloom N, Ramirez SI, Cohn H, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Bajic G, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S, Coelho CH, Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team . PMID: 39036987; PMCID: PMC11566236.
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Correction: Gene expression and chromatin conformation of microglia in virally suppressed people with HIV. Life Sci Alliance. 2025 Jan; 8(1). Schlachetzki JC, Gianella S, Ouyang Z, Lana AJ, Yang X, O'Brien S, Challacombe JF, Gaskill PJ, Jordan-Sciutto KL, Chaillon A, Moore D, Achim CL, Ellis RJ, Smith DM, Glass CK. PMID: 39467638; PMCID: PMC11519389.
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The Infralimbic, but not the Prelimbic Cortex is needed for a Complex Olfactory Memory Task. bioRxiv. 2024 Oct 18. Jun DJ, Shannon R, Tschida K, Smith DM. PMID: 39463969; PMCID: PMC11507807.
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SARS-CoV-2 Plasma Antibody and Nucleocapsid Antigen Status Predict Outcomes in Outpatients With COVID-19. Clin Infect Dis. 2024 10 15; 79(4):920-927. Jilg N, Giganti MJ, Chew KW, Shaw-Saliba K, Ritz J, Moser C, Evering TH, Daar ES, Eron JJ, Currier JS, Hughes MD, Lane HC, Dewar R, Smith DM, Li JZ. PMID: 39018444; PMCID: PMC11478775.
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Pharmacovigilance in the Age of Legalized Cannabis: Using Social Media to Monitor Drug-Drug Interactions Between Immunosuppressants and Cannabis-Derived Products. Drug Saf. 2025 Jan; 48(1):99-105. Allen MR, Wightman GP, Zhu Z, Poliak A, Smith DM, Dredze M, Ayers JW. PMID: 39292423; PMCID: PMC12829999.
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Compromised chronic efficacy of a glucokinase activator AZD1656 in mouse models for common human GCKR variants. Biochem Pharmacol. 2024 11; 229:116499. Ford BE, Chachra SS, Alshawi A, Oakley F, Fairclough RJ, Smith DM, Tiniakos D, Agius L. PMID: 39173844.
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Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2. J Infect Dis. 2024 Aug 16; 230(2):394-402. Choudhary MC, Deo R, Evering TH, Chew KW, Giganti MJ, Moser C, Ritz J, Regan J, Flynn JP, Crain CR, Wohl DA, Currier JS, Eron JJ, Margolis D, Zhu Q, Zhon L, Ya L, Greninger AL, Hughes MD, Smith D, Daar ES, Li JZ. PMID: 38716969; PMCID: PMC11326811.
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An image-based screen for secreted proteins involved in breast cancer G0 cell cycle arrest. Sci Data. 2024 08 10; 11(1):868. Weston WA, Holt JA, Wiecek AJ, Pilling J, Schiavone LH, Smith DM, Secrier M, Barr AR. PMID: 39127790; PMCID: PMC11316812.
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Gene expression and chromatin conformation of microglia in virally suppressed people with HIV. Life Sci Alliance. 2024 Oct; 7(10). Schlachetzki JC, Gianella S, Ouyang Z, Lana AJ, Yang X, O'Brien S, Challacombe JF, Gaskill PJ, Jordan-Sciutto KL, Chaillon A, Moore D, Achim CL, Ellis RJ, Smith DM, Glass CK. PMID: 39060113; PMCID: PMC11282357.
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Risk Analysis of Respiratory Syncytial Virus Among Infants in the United States by Birth Month. J Pediatric Infect Dis Soc. 2024 Jun 28; 13(6):317-327. Gantenberg JR, van Aalst R, Bhuma MR, Limone B, Diakun D, Smith DM, Nelson CB, Bengtson AM, Chaves SS, La Via WV, Rizzo C, Savitz DA, Zullo AR. PMID: 38738450; PMCID: PMC11212365.
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The Retrosplenial Cortical Role in Delayed Spatial Alternation. bioRxiv. 2024 Jun 22. Subramanian DL, Miller AMP, Smith DM. PMID: 38948695; PMCID: PMC11212980.
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ProEnd: A Comprehensive Database for Identifying HbYX Motif-Containing Proteins Across the Tree of Life. bioRxiv. 2024 Jun 09. Salcedo-Tacuma D, Howells G, Mchose C, Gutierrez-Diaz A, Schupp J, Smith DM. PMID: 38895466; PMCID: PMC11185799.
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Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation. JAMA. 2024 05 21; 331(19):1670-1672. Allen MR, Desai N, Namazi A, Leas E, Dredze M, Smith DM, Ayers JW. PMID: 38656757; PMCID: PMC11044002.
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Response to Drs de Grooth and Parienti. J Infect Dis. 2024 May 15; 229(5):1596. Giganti MJ, Chew KW, Eron JJ, Smith DM, Currier JS, Hughes MD. PMID: 38324658; PMCID: PMC11491825.
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Unveiling ecological/evolutionary insights in HIV viral load dynamics: Allowing random slopes to observe correlational changes to CpG-contents and other molecular and clinical predictors. Epidemics. 2024 Jun; 47:100770. Carrasco-Hernández R, Valenzuela-Ponce H, Soto-Nava M, García-Morales C, Matías-Florentino M, Wertheim JO, Smith DM, Reyes-Terán G, Ávila-Ríos S. PMID: 38761432; PMCID: PMC11213286.
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Occult hepatitis B virus infection and current perspectives on global WHO 2030 eradication. J Viral Hepat. 2024 Jul; 31(7):423-431. Saravanan S, Shankar EM, Vignesh R, Ganesh PS, Sankar S, Velu V, Smith DM, Balakrishnan P, Viswanathan D, Govindasamy R, Venkateswaran AR. PMID: 38578122.
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Impact of influenza and pneumococcal vaccines on HIV persistence and immune dynamics during suppressive antiretroviral therapy. AIDS. 2024 07 01; 38(8):1131-1140. Gianella S, Anderson C, Chaillon A, Wells A, Porrachia M, Caballero G, Meneses M, Lonergan J, Woodworth B, Gaitan NC, Rawlings SA, Muttera L, Harkness L, Little SJ, May S, Smith D. PMID: 38526550; PMCID: PMC11141237.
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Time Cells in the Retrosplenial Cortex. bioRxiv. 2024 Mar 03. Subramanian DL, Smith DM. PMID: 38464235; PMCID: PMC10925311.
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Regulate Artificial Intelligence in Health Care by Prioritizing Patient Outcomes. JAMA. 2024 02 27; 331(8):639-640. Ayers JW, Desai N, Smith DM. PMID: 38285467.
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Predictors of HIV rebound differ by timing of antiretroviral therapy initiation. JCI Insight. 2024 02 08; 9(3). Li JZ, Melberg M, Kittilson A, Abdel-Mohsen M, Li Y, Aga E, Bosch RJ, Wonderlich ER, Kinslow J, Giron LB, Di Germanio C, Pilkinton M, MacLaren L, Keefer M, Fox L, Barr L, Acosta E, Ananworanich J, Coombs R, Mellors J, Deeks S, Gandhi RT, Busch M, Landay A, Macatangay B, Smith DM, AIDS Clinical Trials Group A5345 Study Team. PMID: 38329130; PMCID: PMC10967395.
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Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors. ACS Med Chem Lett. 2023 Dec 14; 14(12):1760-1766. Heitmann T, Liao G, de León P, Ernst G, Buchler I, Wei H, Shlevkov E, Brown D, Fitzek M, Collier M, Smith DM, Barrow JC. PMID: 38116421; PMCID: PMC10726443.
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The glucose transporter 2 regulates CD8+ T cell function via environment sensing. Nat Metab. 2023 11; 5(11):1969-1985. Fu H, Vuononvirta J, Fanti S, Bonacina F, D'Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi MP, Grevitt P, Sheikh MH, Solito E, Godinho SA, Bombardieri M, Smith DM, Cooper D, Iqbal AJ, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD, Marelli-Berg FM. PMID: 37884694; PMCID: PMC10663157.
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The Stokes-Einstein-Sutherland Equation at the Nanoscale Revisited. Small. 2024 Feb; 20(6):e2304670. Baer A, Wawra SE, Bielmeier K, Uttinger MJ, Smith DM, Peukert W, Walter J, Smith AS. PMID: 37806757.
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Structure, Function, and Allosteric Regulation of the 20S Proteasome by the 11S/PA28 Family of Proteasome Activators. Biomolecules. 2023 08 29; 13(9). Thomas T, Salcedo-Tacuma D, Smith DM. PMID: 37759726; PMCID: PMC10526260.
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A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature. 2023 06; 618(7963):159-168. Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. PMID: 37225977; PMCID: PMC7614683.
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Integration of functional peptides into nucleic acid-based nanostructures. Nanoscale. 2023 May 04; 15(17):7608-7624. Freitag JS, Möser C, Belay R, Altattan B, Grasse N, Pothineni BK, Schnauß J, Smith DM. PMID: 37042085.
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Systematic altering of semiflexible DNA-based polymer networks via tunable crosslinking. Nanoscale. 2023 Apr 27; 15(16):7374-7383. Glaser M, Mollenkopf P, Prascevic D, Ferraz C, Käs JA, Schnauß J, Smith DM. PMID: 37039012; PMCID: PMC10134436.
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The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326. Mol Metab. 2023 06; 72:101722. Ford BE, Chachra SS, Rodgers K, Moonira T, Al-Oanzi ZH, Anstee QM, Reeves HL, Schattenberg JM, Fairclough RJ, Smith DM, Tiniakos D, Agius L. PMID: 37031802; PMCID: PMC10182400.
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A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target. Stem Cell Reports. 2023 02 14; 18(2):555-569. Davaapil H, McNamara M, Granata A, Macrae RGC, Hirano M, Fitzek M, Aragon-Martin JA, Child A, Smith DM, Sinha S. PMID: 36669494; PMCID: PMC9968988.
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A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets. SLAS Discov. 2023 03; 28(2):3-12. Mullooly N, Smith DM, Gianni D. PMID: 36646173.
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Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes. Sci Adv. 2022 11 18; 8(46):eadd5430. Nag A, Dhindsa RS, Mitchell J, Vasavda C, Harper AR, Vitsios D, Ahnmark A, Bilican B, Madeyski-Bengtson K, Zarrouki B, Zoghbi AW, Wang Q, Smith KR, Alegre-Díaz J, Kuri-Morales P, Berumen J, Tapia-Conyer R, Emberson J, Torres JM, Collins R, Smith DM, Challis B, Paul DS, Bohlooly-Y M, Snowden M, Baker D, Fritsche-Danielson R, Pangalos MN, Petrovski S. PMID: 36383675; PMCID: PMC9668288.
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Pneumomediastinum in COVID-19: a phenotype of severe COVID-19 pneumonitis? The results of the UK POETIC survey. Eur Respir J. 2022 Sep; 60(3). Melhorn J, Achaiah A, Conway FM, Thompson EMF, Skyllberg EW, Durrant J, Hasan NA, Madani Y, Naran P, Vijayakumar B, Tate MJ, Trevelyan GE, Zaki I, Doig CA, Lynch G, Warwick G, Aujayeb A, Jackson KA, Iftikhar H, Noble JH, Ng AYKC, Nugent M, Evans PJ, Hastings RA, Bellenberg HR, Lawrence H, Saville RL, Johl NT, Grey AN, Ellis HC, Chen C, Jones TL, Maddekar N, Khan SL, Muhammad AI, Ghani H, Maung Maung Myint Y, Rafique C, Pippard BJ, Irving BRH, Ali F, Asimba VH, Azam A, Barton EC, Bhatnagar M, Blackburn MP, Millington KJ, Budhram NJ, Bunclark KL, Sapkal TP, Dixon G, Harries AJE, Ijaz M, Karunanithi V, Naik S, Khan MA, Savlani K, Kumar V, Lara Gallego B, Mahdi NA, Morgan C, Patel N, Rowlands EW, Steward MS, Thorley RS, Wollerton RL, Ullah S, Smith DM, Lason W, Rostron AJ, Rahman NM, Hallifax RJ. PMID: 35144988; PMCID: PMC8832377.
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Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function. Diabetes. 2022 07 01; 71(7):1525-1545. Cheung R, Pizza G, Chabosseau P, Rolando D, Tomas A, Burgoyne T, Wu Z, Salowka A, Thapa A, Macklin A, Cao Y, Nguyen-Tu MS, Dickerson MT, Jacobson DA, Marchetti P, Shapiro J, Piemonti L, de Koning E, Leclerc I, Bouzakri K, Sakamoto K, Smith DM, Rutter GA, Martinez-Sanchez A. PMID: 35476777; PMCID: PMC9998846.
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Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase. Diabetologia. 2022 06; 65(6):997-1011. Nguyen-Tu MS, Harris J, Martinez-Sanchez A, Chabosseau P, Hu M, Georgiadou E, Pollard A, Otero P, Lopez-Noriega L, Leclerc I, Sakamoto K, Schmoll D, Smith DM, Carling D, Rutter GA. PMID: 35294578; PMCID: PMC9076735.
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Constraint Release for Reptating Filaments in Semiflexible Networks Depends on Background Fluctuations. Polymers (Basel). 2022 Feb 12; 14(4). Händler T, Tutmarc C, Freitag JS, Smith DM, Schnauß J. PMID: 35215620; PMCID: PMC8879693.
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Phylogenetic Analyses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) B.1.1.7 Lineage Suggest a Single Origin Followed by Multiple Exportation Events Versus Convergent Evolution. Clin Infect Dis. 2021 12 16; 73(12):2314-2317. Chaillon A, Smith DM. PMID: 33772259; PMCID: PMC8083653.
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Dynamics and Dispersal of Local Human Immunodeficiency Virus Epidemics Within San Diego and Across the San Diego-Tijuana Border. Clin Infect Dis. 2021 10 05; 73(7):e2018-e2025. Vrancken B, Mehta SR, Ávila-Ríos S, García-Morales C, Tapia-Trejo D, Reyes-Terán G, Navarro-Álvarez S, Little SJ, Hoenigl M, Pines HA, Patterson T, Strathdee SA, Smith DM, Dellicour S, Chaillon A. PMID: 33079188; PMCID: PMC8492140.
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An Exact Algorithm to Detect the Percolation Transition in Molecular Dynamics Simulations of Cross-Linking Polymer Networks. J Chem Theory Comput. 2021 Oct 12; 17(10):6449-6457. Livraghi M, Höllring K, Wick CR, Smith DM, Smith AS. PMID: 34499497.
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NuSTAR observations of a repeatedly microflaring active region. Mon Not R Astron Soc. 2021 Nov; 507(3):3936-3951. Cooper K, Hannah IG, Grefenstette BW, Glesener L, Krucker S, Hudson HS, White SM, Smith DM, Duncan J. PMID: 35034987; PMCID: PMC8753558.
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Ethical and practical considerations for interventional HIV cure-related research at the end-of-life: A qualitative study with key stakeholders in the United States. PLoS One. 2021; 16(7):e0254148. Kanazawa J, Gianella S, Concha-Garcia S, Taylor J, Kaytes A, Christensen C, Patel H, Ndukwe S, Rawlings S, Hendrickx S, Little S, Brown B, Smith D, Dubé K. PMID: 34270612; PMCID: PMC8284787.
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MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution. Nucleic Acids Res. 2021 07 09; 49(12):e70. Gallardo CM, Wang S, Montiel-Garcia DJ, Little SJ, Smith DM, Routh AL, Torbett BE. PMID: 33849057; PMCID: PMC8266615.
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Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals. Cell Rep Med. 2021 07 20; 2(7):100355. Tarke A, Sidney J, Methot N, Yu ED, Zhang Y, Dan JM, Goodwin B, Rubiro P, Sutherland A, Wang E, Frazier A, Ramirez SI, Rawlings SA, Smith DM, da Silva Antunes R, Peters B, Scheuermann RH, Weiskopf D, Crotty S, Grifoni A, Sette A. PMID: 34230917; PMCID: PMC8249675.
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Scale up rapid research autopsies for tissue immunology. Nature. 2021 07; 595(7867):352. Rawlings SA, Chaillon A, Smith D, Gianella S. PMID: 34257439; PMCID: PMC11140983.
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Cells in Slow Motion: Apparent Undercooling Increases Glassy Behavior at Physiological Temperatures. Adv Mater. 2021 Jul; 33(29):e2101840. Schnauß J, Kunschmann T, Grosser S, Mollenkopf P, Zech T, Freitag JS, Prascevic D, Stange R, Röttger LS, Rönicke S, Smith DM, Bayerl TM, Käs JA. PMID: 34085345.
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Measuring structural parameters of crosslinked and entangled semiflexible polymer networks with single-filament tracing. Phys Rev E. 2021 Jun; 103(6-1):062501. Händler T, Tutmarc C, Glaser M, Freitag JS, Smith DM, Schnauß J. PMID: 34271634.
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Attitudes and perceptions of next-of-kin/loved ones toward end-of-life HIV cure-related research: A qualitative focus group study in Southern California. PLoS One. 2021; 16(5):e0250882. Javadi SS, Mathur K, Concha-Garcia S, Patel H, Perry KE, Lo M, Taylor J, Kaytes A, Little S, Gianella S, Smith D, Dubé K. PMID: 33961653; PMCID: PMC8104928.
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3D Visualization of Immune Cell Populations in HIV-Infected Tissues via Clearing, Immunostaining, Confocal, and Light Sheet Fluorescence Microscopy. J Vis Exp. 2021 05 06; (171). Zhang T, Gupta A, Frederick D, Layman L, Smith DM, Gianella S, Kieffer C. PMID: 34028448; PMCID: PMC10445482.
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HIV Care Prioritization Using Phylogenetic Branch Length. J Acquir Immune Defic Syndr. 2021 04 15; 86(5):626-637. Moshiri N, Smith DM, Mirarab S. PMID: 33394616; PMCID: PMC7933099.
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The Art of Designing DNA Nanostructures with CAD Software. Molecules. 2021 Apr 15; 26(8). Glaser M, Deb S, Seier F, Agrawal A, Liedl T, Douglas S, Gupta MK, Smith DM. PMID: 33920889; PMCID: PMC8071251.
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AI-guided discovery of the invariant host response to viral pandemics. bioRxiv. 2021 Apr 13. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 32995790; PMCID: PMC7523116.
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Can't Work From Home: Pooled Nucleic Acid Testing of Laboratory Workers During the COVID-19 Pandemic. Open Forum Infect Dis. 2021 Jul; 8(7):ofab129. Rawlings SA, Scott B, Layman L, Naranatt P, Heltsley R, Ignacio C, Porrachia M, Gianella S, Smith D, Chaillon A. PMID: 34327248; PMCID: PMC7989168.
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The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation. Am J Physiol Endocrinol Metab. 2021 04 01; 320(4):E846-E857. Zhou AX, Mondal T, Tabish AM, Abadpour S, Ericson E, Smith DM, Knöll R, Scholz H, Kanduri C, Tyrberg B, Althage M. PMID: 33682459.
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RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19. Contemp Clin Trials. 2021 04; 103:106330. Ajmera V, Thompson WK, Smith DM, Malhotra A, Mehta RL, Tolia V, Yin J, Sriram K, Insel PA, Collier S, Richards L, Loomba R. PMID: 33631357; PMCID: PMC7899027.
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Effective HIV Molecular Surveillance Requires Identification of Incident Cases of Infection. Clin Infect Dis. 2021 Feb 15. Little SJ, Chen T, Wang R, Anderson C, Kosakovsky Pond S, Nakazawa M, Mathews WC, DeGruttola V, Smith DM. PMID: 33588434.
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NuSTAR Observation of Energy Release in 11 Solar Microflares. Astrophys J. 2021 Feb 10; 908(1). Duncan J, Glesener L, Grefenstette BW, Vievering J, Hannah IG, Smith DM, Krucker S, White SM, Hudson H. PMID: 35034967; PMCID: PMC8753588.
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Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases. Cell Rep Med. 2021 02 16; 2(2):100204. Tarke A, Sidney J, Kidd CK, Dan JM, Ramirez SI, Yu ED, Mateus J, da Silva Antunes R, Moore E, Rubiro P, Methot N, Phillips E, Mallal S, Frazier A, Rawlings SA, Greenbaum JA, Peters B, Smith DM, Crotty S, Weiskopf D, Grifoni A, Sette A. PMID: 33521695; PMCID: PMC7837622.
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Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science. 2021 02 05; 371(6529). Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. PMID: 33408181; PMCID: PMC7919858.
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DNA Nanostructures in the Fight Against Infectious Diseases. Adv Nanobiomed Res. 2021 Mar; 1(3):2000049. Smith DM, Keller A. PMID: 33615315; PMCID: PMC7883073.
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What the HIV Pandemic Experience Can Teach the United States About the COVID-19 Response. J Acquir Immune Defic Syndr. 2021 01 01; 86(1):1-10. Strathdee SA, Martin NK, Pitpitan EV, Stockman JK, Smith DM. PMID: 33027152; PMCID: PMC7727321.
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Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation. Int J Mol Sci. 2020 Dec 15; 21(24). Parafati M, Bae SH, Kirby RJ, Fitzek M, Iyer P, Engkvist O, Smith DM, Malany S. PMID: 33334026; PMCID: PMC7765409.
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High Prevalence of HIV-1 Drug Resistance and Dynamics of Transmission Among High-Risk Populations in Port-au-Prince, Haiti. J Acquir Immune Defic Syndr. 2020 12 01; 85(4):416-422. Jean Louis F, Domercant JW, Ignacio C, Gianella S, Galbaud G, Leonard M, Smith DM, Chaillon A. PMID: 33136738; PMCID: PMC7592887.
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"[It] is now my responsibility to fulfill that wish:" Clinical and rapid autopsy staff members' experiences and perceptions of HIV reservoir research at the end of life. PLoS One. 2020; 15(11):e0242420. Perry KE, Taylor J, Patel H, Javadi SS, Mathur K, Kaytes A, Concha-Garcia S, Little S, Smith D, Gianella S, Dubé K. PMID: 33206710; PMCID: PMC7673534.
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Comparative Circulation Dynamics of the Five Main HIV Types in China. J Virol. 2020 11 09; 94(23). Vrancken B, Zhao B, Li X, Han X, Liu H, Zhao J, Zhong P, Lin Y, Zai J, Liu M, Smith DM, Dellicour S, Chaillon A. PMID: 32938762; PMCID: PMC7654276.
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Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2020 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2020 10 27; 324(16):1651-1669. Saag MS, Gandhi RT, Hoy JF, Landovitz RJ, Thompson MA, Sax PE, Smith DM, Benson CA, Buchbinder SP, Del Rio C, Eron JJ, Fätkenheuer G, Günthard HF, Molina JM, Jacobsen DM, Volberding PA. PMID: 33052386; PMCID: PMC11017368.
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Grindr Users Take More Risks, but Are More Open to Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis: Could This Dating App Provide a Platform for HIV Prevention Outreach? Clin Infect Dis. 2020 10 23; 71(7):e135-e140. Hoenigl M, Little SJ, Grelotti D, Skaathun B, Wagner GA, Weibel N, Stockman JK, Smith DM. PMID: 31677383; PMCID: PMC7583417.
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Quantifying Public Interest in Police Reforms by Mining Internet Search Data Following George Floyd's Death. J Med Internet Res. 2020 10 21; 22(10):e22574. Ayers JW, Althouse BM, Poliak A, Leas EC, Nobles AL, Dredze M, Smith D. PMID: 33084578; PMCID: PMC7641778.
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In vitro anthelmintic activity of Psidium guajava hydroalcoholic extract against gastro-intestinal sheep nematodes. An Acad Bras Cienc. 2020; 92(suppl 2):e20190074. Silva LP, Debiage RR, Bronzel-JÚnior JL, Silva RMGD, -Peixoto ECTM. PMID: 33084758.
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Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. EMBO J. 2020 11 02; 39(21):e106057. Wang S, Li W, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM. PMID: 32944968; PMCID: PMC7537045.
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Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. bioRxiv. 2020 Sep 23. Song G, He WT, Callaghan S, Anzanello F, Huang D, Ricketts J, Torres JL, Beutler N, Peng L, Vargas S, Cassell J, Parren M, Yang L, Ignacio C, Smith DM, Voss JE, Nemazee D, Ward AB, Rogers T, Burton DR, Andrabi R. PMID: 32995770; PMCID: PMC7523096.
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A small molecule inhibitor of HER3: a proof-of-concept study. Biochem J. 2020 09 18; 477(17):3329-3347. Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. PMID: 32815546; PMCID: PMC7489893.
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Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity. Cell. 2020 11 12; 183(4):996-1012.e19. Rydyznski Moderbacher C, Ramirez SI, Dan JM, Grifoni A, Hastie KM, Weiskopf D, Belanger S, Abbott RK, Kim C, Choi J, Kato Y, Crotty EG, Kim C, Rawlings SA, Mateus J, Tse LPV, Frazier A, Baric R, Peters B, Greenbaum J, Saphire EO, Smith DM, Sette A, Crotty S. PMID: 33010815; PMCID: PMC7494270.
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Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nat Med. 2020 09; 26(9):1339-1350. Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, Spivak AM, Planelles V, Hahn BH, Smith DM, Ho YC, Buzon MJ, Gaebler C, Paiardini M, Li Q, Estes JD, Hope TJ, Kostman J, Mounzer K, Caskey M, Fox L, Frank I, Riley JL, Tebas P, Montaner LJ, BEAT-HIV Delaney Collaboratory to Cure HIV-1 infection. PMID: 32895573; PMCID: PMC7703694.
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Altruism: Scoping review of the literature and future directions for HIV cure-related research. J Virus Erad. 2020 Nov; 6(4):100008. Dubé K, Perry KE, Mathur K, Lo M, Javadi SS, Patel H, Concha-Garcia S, Taylor J, Kaytes A, Dee L, Campbell D, Kanazawa J, Smith D, Gianella S, Auerbach JD, Saberi P, Sauceda JA. PMID: 33294210; PMCID: PMC7695811.
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No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract. Open Forum Infect Dis. 2020 Aug; 7(8):ofaa325. Rawlings SA, Ignacio C, Porrachia M, Du P, Smith DM, Chaillon A. PMID: 32875005; PMCID: PMC7452368.
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Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science. 2020 10 02; 370(6512):89-94. Mateus J, Grifoni A, Tarke A, Sidney J, Ramirez SI, Dan JM, Burger ZC, Rawlings SA, Smith DM, Phillips E, Mallal S, Lammers M, Rubiro P, Quiambao L, Sutherland A, Yu ED, da Silva Antunes R, Greenbaum J, Frazier A, Markmann AJ, Premkumar L, de Silva A, Peters B, Crotty S, Sette A, Weiskopf D. PMID: 32753554; PMCID: PMC7574914.
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Methamphetamine and cardiac disease among people with HIV infection. HIV Med. 2020 11; 21(10):635-641. Martin T, Gianella S, Franklin D, Hsue P, Smith DM. PMID: 32741089; PMCID: PMC7773519.
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Internet Searches About Infectious Diseases Training During the COVID-19 Pandemic. Open Forum Infect Dis. 2020. Birabaharan M, Smith DM, Wooten D. View Publication.
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Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge. Diabetes Obes Metab. 2020 11; 22(11):1985-1994. Ford BE, Chachra SS, Alshawi A, Brennan A, Harnor S, Cano C, Baker DJ, Smith DM, Fairclough RJ, Agius L. PMID: 32519798.
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Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019. J Infect Dis. 2020 06 29; 222(2):206-213. Burbelo PD, Riedo FX, Morishima C, Rawlings S, Smith D, Das S, Strich JR, Chertow DS, Davey RT, Cohen JI. PMID: 32427334; PMCID: PMC7313936.
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Perceptions of Next-of-Kin/Loved Ones About Last Gift Rapid Research Autopsy Study Enrolling People with HIV/AIDS at the End of Life: A Qualitative Interview Study. AIDS Res Hum Retroviruses. 2020 12; 36(12):1033-1046. Dubé K, Patel H, Concha-Garcia S, Perry KE, Mathur K, Javadi SS, Taylor J, Kaytes A, Brown B, Sauceda JA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449624; PMCID: PMC7703245.
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"My Death Will Not [Be] in Vain": Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life. AIDS Res Hum Retroviruses. 2020 12; 36(12):1071-1082. Perry KE, Dubé K, Concha-Garcia S, Patel H, Kaytes A, Taylor J, Javadi SS, Mathur K, Lo M, Brown B, Sauceda JA, Wohl DA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449625; PMCID: PMC7703253.
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Do Sexual Minorities Face Greater Risk for Sexual Harassment, Ever and at School, in Adolescence? : Findings From a 2019 Cross-Sectional Study of U.S. Adults. J Interpers Violence. 2022 02; 37(3-4):NP1963-NP1987. Smith DM, Johns NE, Raj A. PMID: 32571176; PMCID: PMC8574207.
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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science. 2020 08 21; 369(6506):956-963. Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. PMID: 32540903; PMCID: PMC7299280.
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Performing rapid autopsy for the interrogation of HIV reservoirs. AIDS. 2020 06 01; 34(7):1089-1092. Rawlings SA, Layman L, Smith D, Scott B, Ignacio C, Porrachia M, Concha-Garcia S, Hendrickx S, Kaytes A, Taylor J, Gianella S. PMID: 32287073; PMCID: PMC7780881.
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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell. 2020 06 25; 181(7):1489-1501.e15. Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR, Rawlings SA, Sutherland A, Premkumar L, Jadi RS, Marrama D, de Silva AM, Frazier A, Carlin AF, Greenbaum JA, Peters B, Krammer F, Smith DM, Crotty S, Sette A. PMID: 32473127; PMCID: PMC7237901.
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Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events. AIDS. 2020 05 01; 34(6):849-857. Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D. PMID: 32271250; PMCID: PMC7239326.
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Inhibition of the prostaglandin D2-GPR44/DP2 axis improves human islet survival and function. Diabetologia. 2020 07; 63(7):1355-1367. Abadpour S, Tyrberg B, Schive SW, Huldt CW, Gennemark P, Ryberg E, Rydén-Bergsten T, Smith DM, Korsgren O, Skrtic S, Scholz H, Winzell MS. PMID: 32350565; PMCID: PMC7286861.
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NuSTAR Observation of a Minuscule Microflare in a Solar Active Region. Astrophys J Lett. 2020 Apr 20; 893(2). Cooper K, Hannah IG, Grefenstette BW, Glesener L, Krucker S, Hudson HS, White SM, Smith DM. PMID: 35070256; PMCID: PMC8780508.
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Charge-Shifting Polycations Based on N,N-(dimethylamino)ethyl Acrylate for Improving Cytocompatibility During DNA Delivery. ACS Omega. 2020 Apr 28; 5(16):9114-9122. Ros S, Freitag JS, Smith DM, Stöver HDH. PMID: 32363263; PMCID: PMC7191589.
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HIV persists throughout deep tissues with repopulation from multiple anatomical sources. J Clin Invest. 2020 04 01; 130(4):1699-1712. Chaillon A, Gianella S, Dellicour S, Rawlings SA, Schlub TE, De Oliveira MF, Ignacio C, Porrachia M, Vrancken B, Smith DM. PMID: 31910162; PMCID: PMC7108926.
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Tracing the transmission dynamics of HIV-1 CRF55_01B. Sci Rep. 2020 03 20; 10(1):5098. Zai J, Liu H, Lu Z, Chaillon A, Smith D, Li Y, Li X. PMID: 32198405; PMCID: PMC7083841.
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Behavioral Effects of Neuronal, Parent-specific Commd1 Knockout in Mice. Neuroscience. 2020 05 10; 434:1-7. Chase KA, Mallari JE, Tan Y, Sittig L. PMID: 32200079.
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Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors. ACS Pharmacol Transl Sci. 2020 Apr 10; 3(2):305-320. Hendrikse ER, Liew LP, Bower RL, Bonnet M, Jamaluddin MA, Prodan N, Richards KD, Walker CS, Pairaudeau G, Smith DM, Rujan RM, Sudra R, Reynolds CA, Booe JM, Pioszak AA, Flanagan JU, Hay MP, Hay DL. PMID: 32296770; PMCID: PMC7155196.
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Accelerated Electrons Observed Down to <7 keV in a NuSTAR Solar Microflare. Astrophys J Lett. 2020 Mar 10; 891(2). Glesener L, Krucker S, Duncan J, Hannah IG, Grefenstette BW, Chen B, Smith DM, White SM, Hudson H. PMID: 35070255; PMCID: PMC8780722.
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Cryopreservation of DNA Origami Nanostructures. Small. 2020 04; 16(13):e1905959. Xin Y, Kielar C, Zhu S, Sikeler C, Xu X, Möser C, Grundmeier G, Liedl T, Heuer-Jungemann A, Smith DM, Keller A. PMID: 32130783.
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HIV Prevention Method Preferences Within Sexual Partnerships Reported by HIV-Negative MSM and TW in Tijuana, Mexico. AIDS Behav. 2020 Mar; 24(3):839-846. Pines HA, Patrick R, Smith DM, Harvey-Vera A, Blumenthal JS, Rangel G, Semple SJ, Patterson TL. PMID: 30945030; PMCID: PMC6776706.
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Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet. Clin Infect Dis. 2020 02 14; 70(5):925-932. Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M. PMID: 30953067; PMCID: PMC7319271.
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Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition. Cell Death Discov. 2020; 6:6. Brito H, Marques V, Afonso MB, Brown DG, Börjesson U, Selmi N, Smith DM, Roberts IO, Fitzek M, Aniceto N, Guedes RC, Moreira R, Rodrigues CMP. PMID: 32123582; PMCID: PMC7026080.
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Healthcare Costs of Potential Glucocorticoid-Associated Adverse Events in Patients with Giant Cell Arteritis. Clinicoecon Outcomes Res. 2019; 11:799-807. Best JH, Kong AM, Smith DM, Abbass I, Michalska M. PMID: 31920351; PMCID: PMC6934125.
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Hippocampal state transitions at the boundaries between trial epochs. Hippocampus. 2020 06; 30(6):582-595. Bulkin DA, Sinclair DG, Law LM, Smith DM. PMID: 31793687; PMCID: PMC11127720.
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Exploring Reactive Conformations of Coenzyme A during Binding and Unbinding to Pyruvate Formate-Lyase. J Phys Chem A. 2019 Oct 31; 123(43):9345-9356. Hanževacki M, Banhatti RD, Condic-Jurkic K, Smith AS, Smith DM. PMID: 31580071.
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Correction: The role of stickiness in the rheology of semiflexible polymers. Soft Matter. 2019 Oct 28; 15(40):8184. Golde T, Glaser M, Tutmarc C, Elbalasy I, Huster C, Busteros G, Smith DM, Herrmann H, Käs JA, Schnauß J. PMID: 31576888.
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Response to: Is Burnout Infectious? Understanding Drivers of Burnout and Job Satisfaction Among Academic Infectious Diseases Physicians. Open Forum Infect Dis. 2019 Oct; 6(10):ofz378. Wooten D, Smith D. PMID: 31660342; PMCID: PMC6786503.
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Exercise training prevents the perivascular adipose tissue-induced aortic dysfunction with metabolic syndrome. Redox Biol. 2019 09; 26:101285. DeVallance E, Branyan KW, Lemaster KC, Anderson R, Marshall KL, Olfert IM, Smith DM, Kelley EE, Bryner RW, Frisbee JC, Chantler PD. PMID: 31374361; PMCID: PMC6669320.
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Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability. Molecules. 2019 Jul 16; 24(14). Kielar C, Xin Y, Xu X, Zhu S, Gorin N, Grundmeier G, Möser C, Smith DM, Keller A. PMID: 31315177; PMCID: PMC6680526.
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The role of stickiness in the rheology of semiflexible polymers. Soft Matter. 2019 Jun 19; 15(24):4865-4872. Golde T, Glaser M, Tutmarc C, Elbalasy I, Huster C, Busteros G, Smith DM, Herrmann H, Käs JA, Schnauß J. PMID: 31161188.
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Water balloon-induced orbital fracture in an aviator. Mil Med Res. 2019 06 11; 6(1):17. Holland TE, Smith DM, Gibson GN, Brinkerhoff JG. PMID: 31182165; PMCID: PMC6558684.
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Insights from molecular dynamics simulations on structural organization and diffusive dynamics of an ionic liquid at solid and vacuum interfaces. J Colloid Interface Sci. 2019 Oct 01; 553:350-363. Vucemilovic-Alagic N, Banhatti RD, Stepic R, Wick CR, Berger D, Gaimann MU, Baer A, Harting J, Smith DM, Smith AS. PMID: 31220709.
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Pooled nucleic acid testing strategy for monitoring HIV-1 treatment in resource limited settings. J Clin Virol. 2019 08; 117:56-60. J B, Tr D, S G, E E, A P, D C, Kg M, P B, S S, Ss S, N K, Dm S, S S. PMID: 31212189.
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Mechanism of Action of Methotrexate Against Zika Virus. Viruses. 2019 04 10; 11(4). Beck S, Zhu Z, Oliveira MF, Smith DM, Rich JN, Bernatchez JA, Siqueira-Neto JL. PMID: 30974762; PMCID: PMC6521145.
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Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015. Open Forum Infect Dis. 2019 Apr; 6(4):ofz160. Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK. PMID: 31041355; PMCID: PMC6483132.
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HIV-1 drug resistance before initiation or re-initiation of first-line ART in eight regions of Mexico: a sub-nationally representative survey. J Antimicrob Chemother. 2019 04 01; 74(4):1044-1055. Ávila-Ríos S, García-Morales C, Valenzuela-Lara M, Chaillon A, Tapia-Trejo D, Pérez-García M, López-Sánchez DM, Maza-Sánchez L, Del Arenal-Sánchez SJ, Paz-Juárez HE, Quiroz-Morales VS, Mehta SR, Smith DM, León-Juárez EA, Magis-Rodríguez C, Reyes-Terán G, HIVDR MexNet Group. PMID: 30597094; PMCID: PMC7939069.
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Herd Immunity Likely Protected the Men Who Have Sex With Men in the Recent Hepatitis A Outbreak in San Diego, California. Clin Infect Dis. 2019 03 19; 68(7):1228-1230. Smith D, Huynh C, Moore AJ, Frick A, Anderson C, Porrachia M, Scott B, Stous S, Schooley R, Little S, Santos AT. PMID: 30052941; PMCID: PMC7182127.
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AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue. Nat Metab. 2019 03; 1(3):340-349. Pollard AE, Martins L, Muckett PJ, Khadayate S, Bornot A, Clausen M, Admyre T, Bjursell M, Fiadeiro R, Wilson L, Whilding C, Kotiadis VN, Duchen MR, Sutton D, Penfold L, Sardini A, Bohlooly-Y M, Smith DM, Read JA, Snowden MA, Woods A, Carling D. PMID: 30887000; PMCID: PMC6420092.
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Challenges in Quantifying Cytosine Methylation in the HIV Provirus. mBio. 2019 01 22; 10(1). LaMere SA, Chaillon A, Huynh C, Smith DM, Gianella S. PMID: 30670613; PMCID: PMC6343035.
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Urotensin II in the development and progression of chronic kidney disease following ⅚ nephrectomy in the rat. Exp Physiol. 2019 03; 104(3):421-433. Eyre HJ, Speight T, Glazier JD, Smith DM, Ashton N. PMID: 30575177; PMCID: PMC6492238.
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A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PLoS Negl Trop Dis. 2018 12; 12(12):e0007053. Carlin AF, Wen J, Vizcarra EA, McCauley M, Chaillon A, Akrami K, Kim C, Ngono AE, Lara-Marquez ML, Smith DM, Glass CK, Schooley RT, Benner C, Shresta S. PMID: 30596671; PMCID: PMC6329527.
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Baseline Genotype Testing to Assess Drug Resistance Before Beginning HIV Treatment-Reply. JAMA. 2018 11 27; 320(20):2154. Saag MS, Günthard HF, Smith DM. PMID: 30480722; PMCID: PMC6415747.
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Pinpointed Stimulation of EphA2 Receptors via DNA-Templated Oligovalence. Int J Mol Sci. 2018 Nov 06; 19(11). Möser C, Lorenz JS, Sajfutdinow M, Smith DM. PMID: 30404153; PMCID: PMC6274923.
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The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241; PMCID: PMC6217727.
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Growth of HIV-1 Molecular Transmission Clusters in New York City. J Infect Dis. 2018 11 05; 218(12):1943-1953. Wertheim JO, Murrell B, Mehta SR, Forgione LA, Kosakovsky Pond SL, Smith DM, Torian LV. PMID: 30010850; PMCID: PMC6217720.
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Influenza Vaccination Can Broadly Activate the HIV Reservoir During Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2018 11 01; 79(3):e104-e107. Christensen-Quick A, Chaillon A, Yek C, Zanini F, Jordan P, Ignacio C, Caballero G, Gianella S, Smith D. PMID: 30085954; PMCID: PMC6185804.
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Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics. 2018 10 20; 19(1):83. Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D. PMID: 30342507; PMCID: PMC6196016.
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Predictors of systemic therapy sequences following a CDK 4/6 inhibitor-based regimen in post-menopausal women with hormone receptor positive, HEGFR-2 negative metastatic breast cancer. Curr Med Res Opin. 2019 01; 35(1):73-80. Princic N, Aizer A, Tang DH, Smith DM, Johnson W, Bardia A. PMID: 30175631.
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Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2018 07 24; 320(4):379-396. Saag MS, Benson CA, Gandhi RT, Hoy JF, Landovitz RJ, Mugavero MJ, Sax PE, Smith DM, Thompson MA, Buchbinder SP, Del Rio C, Eron JJ, Fätkenheuer G, Günthard HF, Molina JM, Jacobsen DM, Volberding PA. PMID: 30043070; PMCID: PMC6415748.
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Willingness to participate in HIV research at the end of life (EOL). PLoS One. 2018; 13(7):e0199670. Prakash K, Gianella S, Dubé K, Taylor J, Lee G, Smith DM. PMID: 30036365; PMCID: PMC6056048.
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Force-Induced Unravelling of DNA Origami. ACS Nano. 2018 07 24; 12(7):6734-6747. Engel MC, Smith DM, Jobst MA, Sajfutdinow M, Liedl T, Romano F, Rovigatti L, Louis AA, Doye JPK. PMID: 29851456.
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Direct observation and rational design of nucleation behavior in addressable self-assembly. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):E5877-E5886. Sajfutdinow M, Jacobs WM, Reinhardt A, Schneider C, Smith DM. PMID: 29891671; PMCID: PMC6042111.
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SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy. PLoS Pathog. 2018 05; 14(5):e1007071. Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR, Jones KA. PMID: 29791506; PMCID: PMC5988312.
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Erratum to: Factors Associated with Mood Disorder Diagnosis Among a Population Based Cohort of Men and Women Living With and Without HIV in British Columbia Between 1998 and 2012. AIDS Behav. 2018 05; 22(5):1541. Closson K, Osborne C, Smith DM, Kesselring S, Eyawo O, Card K, Sereda P, Jabbari S, Franco-Villalobos C, Ahmed T, Gabler K, Patterson T, Hull M, Montaner JSG, Hogg RS, Comparative Outcomes and Services utilization Trends (COAST) study. PMID: 28741132.
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Factors Associated with Mood Disorder Diagnosis Among a Population Based Cohort of Men and Women Living With and Without HIV in British Columbia Between 1998 and 2012. AIDS Behav. 2018 05; 22(5):1530-1540. Closson K, Osborne C, Smith DM, Kesselring S, Eyawo O, Card K, Sereda P, Jabbari S, Franco-Villalobos C, Ahmed T, Gabler K, Patterson T, Hull M, Montaner JSG, Hogg RS, Comparative Outcomes and Services utilization Trends (COAST) study. PMID: 28612214.
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The Importance of Human Immunodeficiency Virus Research for Transgender and Gender-Nonbinary Individuals. Clin Infect Dis. 2018 04 17; 66(9):1460-1466. Gianella S, Sonya Haw J, Blumenthal J, Sullivan B, Smith D. PMID: 29126186; PMCID: PMC5905620.
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Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors. AIDS. 2018 02 20; 32(4):443-450. Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith DM, Little SJ, Lauffenburger DA, Richman DD, Alter G. PMID: 29239894; PMCID: PMC5983383.
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Occult HBV infection in HIV-infected adults and evaluation of pooled NAT for HBV. J Viral Hepat. 2018 06; 25(6):718-723. Dinesha TR, Boobalan J, Sivamalar S, Subashini D, Solomon SS, Murugavel KG, Balakrishnan P, Smith DM, Saravanan S. PMID: 29316078; PMCID: PMC5980682.
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Synthetic Transient Crosslinks Program the Mechanics of Soft, Biopolymer-Based Materials. Adv Mater. 2018 Mar; 30(13):e1706092. Lorenz JS, Schnauß J, Glaser M, Sajfutdinow M, Schuldt C, Käs JA, Smith DM. PMID: 29446165; PMCID: PMC5878933.
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Impact of Public Safety Policies on Human Immunodeficiency Virus Transmission Dynamics in Tijuana, Mexico. Clin Infect Dis. 2018 02 10; 66(5):758-764. Mehta SR, Chaillon A, Gaines TL, Gonzalez-Zuniga PE, Stockman JK, Almanza-Reyes H, Chavez JR, Vera A, Wagner KD, Patterson TL, Scott B, Smith DM, Strathdee SA. PMID: 29045592; PMCID: PMC5848227.
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Mortality among people living with HIV/AIDS with non-small-cell lung cancer in the modern HAART Era. AIDS Care. 2018 07; 30(7):936-942. Smith DM, Salters KA, Eyawo O, Franco-Villalobos C, Jabbari S, Wiseman SM, Press N, Montaner JSG, Man SFP, Hull M, Hogg RS. PMID: 29411625.
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Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol. 2018 02 01; 92(3). Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM. PMID: 29142136; PMCID: PMC5774877.
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HIV, Hepatitis B Virus, and Hepatitis C Virus Prevalence Among High-Risk Populations in South India. AIDS Res Hum Retroviruses. 2018 04; 34(4):327-328. Dinesha TR, Boobalan J, Sivamalar S, Solomon SS, Poongulali S, Pradeep A, Murugavel KG, Balakrishnan P, Smith DM, Saravanan S. PMID: 29161880; PMCID: PMC5899286.
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Suicide Risk Behaviors Among Sexual Minority Adolescents in the United States, 2015. JAMA. 2017 12 19; 318(23):2349-2351. Caputi TL, Smith D, Ayers JW. PMID: 29260214; PMCID: PMC5820699.
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HIV Prevalence and Risk Behaviors in Male to Female (MTF) Transgender Persons in Tijuana, Mexico. AIDS Behav. 2017 Dec; 21(12):3271-3278. Salas-Espinoza KJ, Menchaca-Diaz R, Patterson TL, Urada LA, Smith D, Strathdee SA, Pitpitan EV. PMID: 29032411; PMCID: PMC5736304.
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HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity. 2017 11 21; 47(5):990-1003.e9. Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, Wrin T, Algate P, Chan-Hui PY, Karita E, IAVI Protocol C Investigators, IAVI African HIV Research Network, Ward AB, Wilson IA, Burton DR, Smith D, Pond SLK, Poignard P. PMID: 29166592; PMCID: PMC5736302.
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Agonism of free fatty acid receptors 1 and 4 generates peptide YY-mediated inhibitory responses in mouse colon. Br J Pharmacol. 2017 Dec; 174(23):4508-4522. Moodaley R, Smith DM, Tough IR, Schindler M, Cox HM. PMID: 28971469; PMCID: PMC5715575.
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Jamming transitions in cancer. J Phys D Appl Phys. 2017 Oct 27; 50(48):483001. Oswald L, Grosser S, Smith DM, Käs JA. PMID: 29628530; PMCID: PMC5884432.
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DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers. J Vis Exp. 2017 10 25; (128). Schnauß J, Glaser M, Lorenz JS, Schuldt C, Möser C, Sajfutdinow M, Händler T, Käs JA, Smith DM. PMID: 29155710; PMCID: PMC5755217.
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No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol. 2017 11 01; 91(21). Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S. PMID: 28794047; PMCID: PMC5640831.
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Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection. Antimicrob Agents Chemother. 2017 10; 61(10). Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. PMID: 28807909; PMCID: PMC5610518.
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Network oscillatory activity driven by context memory processing is differently regulated by glutamatergic and cholinergic neurotransmission. Neurobiol Learn Mem. 2017 Nov; 145:59-66. Miller AMP, Frick BJ, Smith DM, Radulovic J, Corcoran KA. PMID: 28864239; PMCID: PMC5698163.
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Dapagliflozin slows the progression of the renal and liver fibrosis associated with type 2 diabetes. Am J Physiol Endocrinol Metab. 2017 11 01; 313(5):E563-E576. Tang L, Wu Y, Tian M, Sjöström CD, Johansson U, Peng XR, Smith DM, Huang Y. PMID: 28811292.
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Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol. 2017 09 01; 91(17). Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. PMID: 28615205; PMCID: PMC5553187.
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Identification of putative unique immunogenic ZIKV and DENV1-4 peptides for diagnostic cellular based tests. Sci Rep. 2017 07 24; 7(1):6218. Oom AL, Smith D, Akrami K. PMID: 28740150; PMCID: PMC5524841.
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Comparison of all-cause, stroke, and bleed-specific healthcare resource utilization among patients with non-valvular atrial fibrillation (NVAF) and newly treated with dabigatran or warfarin. Expert Rev Pharmacoecon Outcomes Res. 2019 Apr; 19(2):213-222. Song X, Gandhi P, Gilligan AM, Arora P, Wang C, Henriques C, Sander S, Smith DM. PMID: 28649894.
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Molecular Features of the V1-V4 Coding Region of Sexually Transmitted Human Immunodeficiency Virus Type 1. J Infect Dis. 2017 05 15; 215(10):1506-1513. Choi JY, Pond SLK, Anderson CM, Richman DD, Smith DM. PMID: 28419276; PMCID: PMC6281333.
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Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats. Diabetes. 2017 07; 66(7):2007-2018. Trevaskis JL, Sacramento CB, Jouihan H, Ali S, Le Lay J, Oldham S, Bhagroo N, Boland BB, Cann J, Chang Y, O'Day T, Howard V, Reers C, Winzell MS, Smith DM, Feigh M, Barkholt P, Schreiter K, Austen M, Andag U, Thompson S, Jermutus L, Coghlan MP, Grimsby J, Dohrmann C, Rhodes CJ, Rondinone CM, Sharma A. PMID: 28408435.
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Short Communication: HIV-1 Transmission Networks Across South Korea. AIDS Res Hum Retroviruses. 2017 08; 33(8):827-831. Ahn MY, Wertheim JO, Kim WJ, Kim SW, Lee JS, Ann HW, Jeon Y, Ahn JY, Song JE, Oh DH, Kim YC, Kim EJ, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Smith DM, Choi JY. PMID: 28346838; PMCID: PMC5564048.
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Dapagliflozin-lowered blood glucose reduces respiratory Pseudomonas aeruginosa infection in diabetic mice. Br J Pharmacol. 2017 05; 174(9):836-847. Åstrand A, Wingren C, Benjamin A, Tregoning JS, Garnett JP, Groves H, Gill S, Orogo-Wenn M, Lundqvist AJ, Walters D, Smith DM, Taylor JD, Baker EH, Baines DL. PMID: 28192604; PMCID: PMC5386993.
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Dynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization-case study. J Neurovirol. 2017 06; 23(3):460-473. de Almeida SM, Rotta I, Ribeiro CE, Oliveira MF, Chaillon A, de Pereira AP, Cunha AP, Zonta M, Bents JF, Raboni SM, Smith D, Letendre S, Ellis RJ. PMID: 28247269; PMCID: PMC5441962.
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Lyophilized visually readable loop-mediated isothermal reverse transcriptase nucleic acid amplification test for detection Ebola Zaire RNA. J Virol Methods. 2017 06; 244:32-38. Carter C, Akrami K, Hall D, Smith D, Aronoff-Spencer E. PMID: 28242293; PMCID: PMC5568651.
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Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies. Retrovirology. 2017 Feb 21; 14(1):15. Chaillon A, Essat A, Frange P, Smith DM, Delaugerre C, Barin F, Ghosn J, Pialoux G, Robineau O, Rouzioux C, Goujard C, Meyer L, Chaix ML, on behalf the ANRS PRIMO Cohort Study. PMID: 28222757; PMCID: PMC5322782.
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Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis. 2017 02 15; 64(4):428-434. Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S. PMID: 28174909; PMCID: PMC5849030.
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Development of a novel algorithm to determine adherence to chronic pain treatment guidelines using administrative claims. J Pain Res. 2017; 10:327-339. Margolis JM, Princic N, Smith DM, Abraham L, Cappelleri JC, Shah SN, Park PW. PMID: 28223842; PMCID: PMC5308584.
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Now is the Time to Study the Timing of Influenza Vaccine. HIV Med. 2018 03; 19(3):e53. Glinka ER, Smith DM, Johns ST. PMID: 28116796.
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Partner services in adults with acute and early HIV infection. AIDS. 2017 01 14; 31(2):287-293. Green N, Hoenigl M, Chaillon A, Anderson CM, Kosakovsky Pond SL, Smith DM, Little SJ. PMID: 27831950; PMCID: PMC5177524.
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Social and Genetic Networks of HIV-1 Transmission in New York City. PLoS Pathog. 2017 01; 13(1):e1006000. Wertheim JO, Kosakovsky Pond SL, Forgione LA, Mehta SR, Murrell B, Shah S, Smith DM, Scheffler K, Torian LV. PMID: 28068413; PMCID: PMC5221827.
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Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 01; 13(1):e1006112. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. PMID: 28046096; PMCID: PMC5266327.
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Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 01 02; 31(1):1-4. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. PMID: 27755112; PMCID: PMC5137789.
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HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection. J Acquir Immune Defic Syndr. 2017 01 01; 74(1):95-102. Chaillon A, Smith DM, Vanpouille C, Lisco A, Jordan P, Caballero G, Vargas M, Gianella S, Mehta SR. PMID: 27548440; PMCID: PMC5140710.
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Etravirine and Rilpivirine Drug Resistance Among HIV-1 Subtype C Infected Children Failing Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimens in South India. AIDS Res Hum Retroviruses. 2017 06; 33(6):567-574. Saravanan S, Kausalya B, Gomathi S, Sivamalar S, Pachamuthu B, Selvamuthu P, Pradeep A, Sunil S, Mothi SN, Smith DM, Kantor R. PMID: 27869478; PMCID: PMC5695734.
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Identification of Two New HIV-1 Circulating Recombinant Forms (CRF87_cpx and CRF88_BC) from Reported Unique Recombinant Forms in Asia. AIDS Res Hum Retroviruses. 2017 04; 33(4):353-358. Hu Y, Wan Z, Zhou YH, Smith D, Zheng YT, Zhang C. PMID: 27762598; PMCID: PMC5372766.
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Evaluating increased resource use in fibromyalgia using electronic health records. Clinicoecon Outcomes Res. 2016; 8:675-683. Margolis JM, Masters ET, Cappelleri JC, Smith DM, Faulkner S. PMID: 27895505; PMCID: PMC5117947.
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HIV-associated neurocognitive disorder is associated with HIV-1 dual infection. AIDS. 2016 11 13; 30(17):2591-2597. Wagner GA, Chaillon A, Liu S, Franklin DR, Caballero G, Kosakovsky Pond SL, Vaida F, Heaton RK, Letendre SL, Grant I, Richman DD, Smith DM. PMID: 27536983; PMCID: PMC5083206.
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Internal Cholinergic Regulation of Learning and Recall in a Model of Olfactory Processing. Front Cell Neurosci. 2016; 10:256. de Almeida L, Idiart M, Dean O, Devore S, Smith DM, Linster C. PMID: 27877112; PMCID: PMC5099168.
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Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection. J Neuroimmunol. 2016 12 15; 301:41-48. de Almeida SM, Rotta I, Ribeiro CE, Smith D, Wang R, Judicello J, Potter M, Vaida F, Letendre S, Ellis RJ, HNRC Group. PMID: 27836178; PMCID: PMC5148696.
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A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine (Baltimore). 2016 Nov; 95(44):e5315. Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. PMID: 27858912; PMCID: PMC5591160.
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Tuning Synthetic Semiflexible Networks by Bending Stiffness. Phys Rev Lett. 2016 Nov 04; 117(19):197801. Schuldt C, Schnauß J, Händler T, Glaser M, Lorenz J, Golde T, Käs JA, Smith DM. PMID: 27858441.
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Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults. Clin Infect Dis. 2016 Dec 15; 63(12):1655-1660. Bharti AR, McCutchan A, Deutsch R, Smith DM, Ellis RJ, Cherner M, Woods SP, Heaton RK, Grant I, Letendre SL. PMID: 27794019; PMCID: PMC5146725.
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(1→3)-β-d-Glucan: A Biomarker for Microbial Translocation in Individuals with Acute or Early HIV Infection? Front Immunol. 2016; 7:404. Hoenigl M, Pérez-Santiago J, Nakazawa M, de Oliveira MF, Zhang Y, Finkelman MA, Letendre S, Smith D, Gianella S. PMID: 27752257; PMCID: PMC5046804.
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Slow stabilization of concurrently acquired hippocampal context representations. Hippocampus. 2016 12; 26(12):1560-1569. Law LM, Bulkin DA, Smith DM. PMID: 27650572; PMCID: PMC5138051.
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Standard vaccines increase HIV-1 transcription during antiretroviral therapy. AIDS. 2016 09 24; 30(15):2289-98. Yek C, Gianella S, Plana M, Castro P, Scheffler K, García F, Massanella M, Smith DM. PMID: 27427877; PMCID: PMC5559226.
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Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment. Clin Infect Dis. 2016 Dec 01; 63(11):1517-1524. Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S. PMID: 27601222; PMCID: PMC5106612.
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First description of two new HIV-1 recombinant forms CRF82_cpx and CRF83_cpx among drug users in Northern Myanmar. Virulence. 2017 07 04; 8(5):497-503. Chen X, Ye M, Duo L, Pang W, Smith D, Zhang C, Zheng YT. PMID: 27574950; PMCID: PMC5538334.
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First Appearance of HIV-1 CRF07_BC and CRF08_BC Outside China. AIDS Res Hum Retroviruses. 2017 01; 33(1):74-76. Chen X, Ye M, Pang W, Smith DM, Zhang C, Zheng YT. PMID: 27392826; PMCID: PMC5749047.
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Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions. J Infect. 2016 11; 73(5):476-484. Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ. PMID: 27521468; PMCID: PMC5143169.
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Comparison of adherence and persistence among adults with type 2 diabetes mellitus initiating saxagliptin or linagliptin. Patient Prefer Adherence. 2016; 10:1471-9. Farr AM, Sheehan JJ, Davis BM, Smith DM. PMID: 27540280; PMCID: PMC4979597.
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Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy. Virus Evol. 2016 Jul; 2(2):vew020. Gianella S, Kosakovsky Pond SL, Oliveira MF, Scheffler K, Strain MC, De la Torre A, Letendre S, Smith DM, Ellis RJ. PMID: 27774305; PMCID: PMC5072458.
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Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2016 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2016 Jul 12; 316(2):191-210. Günthard HF, Saag MS, Benson CA, del Rio C, Eron JJ, Gallant JE, Hoy JF, Mugavero MJ, Sax PE, Thompson MA, Gandhi RT, Landovitz RJ, Smith DM, Jacobsen DM, Volberding PA. PMID: 27404187; PMCID: PMC5012643.
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Biomarkers of chemotaxis and inflammation in cerebrospinal fluid and serum in individuals with HIV-1 subtype C versus B. J Neurovirol. 2016 12; 22(6):715-724. de Almeida SM, Rotta I, Jiang Y, Li X, Raboni SM, Ribeiro CE, Smith D, Potter M, Vaida F, Letendre S, Ellis RJ, HNRC Group. PMID: 27400932; PMCID: PMC5130607.
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Rapid Sequencing of Complete env Genes from Primary HIV-1 Samples. Virus Evol. 2016 Jul; 2(2):vew018. Laird Smith M, Murrell B, Eren K, Ignacio C, Landais E, Weaver S, Phung P, Ludka C, Hepler L, Caballero G, Pollner T, Guo Y, Richman D, IAVI Protocol C Investigators & The IAVI African HIV Research Network, Poignard P, Paxinos EE, Kosakovsky Pond SL, Smith DM. PMID: 29492273; PMCID: PMC5822884.
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The dynamics of the HIV epidemic among men who have sex with men (MSM) from 2005 to 2012 in Shenzhen, China. Sci Rep. 2016 06 29; 6:28703. Zhao J, Chen L, Chaillon A, Zheng C, Cai W, Yang Z, Li G, Gan Y, Wang X, Hu Y, Zhong P, Zhang C, Smith DM. PMID: 27352965; PMCID: PMC4926087.
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A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics. Sci Rep. 2016 06 24; 6:28707. Chaillon A, Hoenigl M, Mehta SR, Weibel N, Little SJ, Smith DM. PMID: 27337983; PMCID: PMC4919622.
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The Veterans Aging Cohort Study (VACS) Index and Neurocognitive Change: A Longitudinal Study. Clin Infect Dis. 2016 Sep 01; 63(5):694-702. Marquine MJ, Montoya JL, Umlauf A, Fazeli PL, Gouaux B, Heaton RK, Ellis RJ, Letendre SL, Grant I, Moore DJ, HIV Neurobehavioral Research Program Group. PMID: 27199461; PMCID: PMC4981756.
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Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clin Infect Dis. 2016 07 01; 63(1):101-107. Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. PMID: 27174704; PMCID: PMC4901863.
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Characteristics of Resting-State Functional Connectivity in HIV-Associated Neurocognitive Disorder. PLoS One. 2016; 11(4):e0153493. Ann HW, Jun S, Shin NY, Han S, Ahn JY, Ahn MY, Jeon YD, Jung IY, Kim MH, Jeong WY, Ku NS, Kim JM, Smith DM, Choi JY. PMID: 27104345; PMCID: PMC4841538.
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Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men. J Acquir Immune Defic Syndr. 2016 Apr 15; 71(5):551-7. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Smith DM, Little SJ. PMID: 26536321; PMCID: PMC4788567.
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Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection. J Virol. 2016 Apr; 90(8):3944-3952. Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM. PMID: 26842469; PMCID: PMC4810527.
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Molecular epidemiology identifies HIV transmission networks associated with younger age and heterosexual exposure among Korean individuals. J Med Virol. 2016 10; 88(10):1832-5. Chin BS, Chaillon A, Mehta SR, Wertheim JO, Kim G, Shin HS, Smith DM. PMID: 26990771; PMCID: PMC4969179.
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Mitochondrial injury and cognitive function in HIV infection and methamphetamine use. AIDS. 2016 Mar 27; 30(6):839-48. Var SR, Day TR, Vitomirov A, Smith DM, Soontornniyomkij V, Moore DJ, Achim CL, Mehta SR, Pérez-Santiago J. PMID: 26807965; PMCID: PMC4785088.
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Shedding of Hepatitis C Virus in Semen of Human Immunodeficiency Virus-Infected Men. Open Forum Infect Dis. 2016 Mar; 3(2):ofw057. Turner SS, Gianella S, Yip MJ, van Seggelen WO, Gillies RD, Foster AL, Barbati ZR, Smith DM, Fierer DS. PMID: 27186582; PMCID: PMC4866572.
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Validation of the GeneXpert® CT/NG Assay for use with Male Pharyngeal and Rectal Swabs. Austin J HIV AIDS Res. 2016; 3(1). Geiger R, Smith DM, Little SJ, Mehta SR. PMID: 27536736; PMCID: PMC4985020.
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Neurobehavioral Disturbances During Acute and Early HIV Infection. Cogn Behav Neurol. 2016 Mar; 29(1):1-10. Kamat R, Doyle KL, Iudicello JE, Morgan EE, Morris S, Smith DM, Little SJ, Grant I, Woods SP, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 27008244; PMCID: PMC4806542.
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Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening. Emerg Infect Dis. 2016 Mar; 22(3):532-4. Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ. PMID: 26890854; PMCID: PMC4766914.
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A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers. Oncotarget. 2016 Feb 02; 7(5):6159-74. Hanley CJ, Noble F, Ward M, Bullock M, Drifka C, Mellone M, Manousopoulou A, Johnston HE, Hayden A, Thirdborough S, Liu Y, Smith DM, Mellows T, Kao WJ, Garbis SD, Mirnezami A, Underwood TJ, Eliceiri KW, Thomas GJ. PMID: 26716418; PMCID: PMC4868747.
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Prevalence of Transmitted HIV Drug Resistance Among Recently Infected Persons in San Diego, CA 1996-2013. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):228-36. Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. PMID: 26413846; PMCID: PMC4712087.
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Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series. Open Forum Infect Dis. 2016 Jan; 3(1):ofw014. Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM. PMID: 26925432; PMCID: PMC4766383.
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Timing Matters - Influenza Vaccination to HIV-Infected Patients. HIV Med. 2016 09; 17(8):601-4. Glinka ER, Smith DM, Johns ST. PMID: 26810556; PMCID: PMC4960000.
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Corrigendum: Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2016 Jan 19; 6:19387. de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. PMID: 26783252; PMCID: PMC4726116.
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Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection. AIDS. 2016 Jan; 30(2):193-201. Vanpouille C, Introini A, Morris SR, Margolis L, Daar ES, Dube MP, Little SJ, Smith DM, Lisco A, Gianella S. PMID: 26558730; PMCID: PMC4862605.
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A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines. Cancer Lett. 2016 Feb 28; 371(2):285-91. Shi Y, Wang J, Wang Y, Wang A, Guo H, Wei F, Mehta SR, Espitia S, Smith DM, Liu L, Zhang Y, Chen D. PMID: 26706415; PMCID: PMC4934374.
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Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2015 Nov 25; 5:17094. de Oliveira MF, Murrell B, Murrel B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. PMID: 26603568; PMCID: PMC4658529.
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Pooled Nucleic Acid Testing to Detect Antiretroviral Treatment Failure in HIV-Infected Patients in Mozambique. J Acquir Immune Defic Syndr. 2015 Nov 01; 70(3):256-61. Tilghman M, Tsai D, Buene TP, Tomas M, Amade S, Gehlbach D, Chang S, Ignacio C, Caballero G, Espitia S, May S, Noormahomed EV, Smith DM. PMID: 26135327; PMCID: PMC4607635.
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No evidence of posttreatment control after early initiation of antiretroviral therapy. AIDS. 2015 Oct 23; 29(16):2093-7. Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 26544575; PMCID: PMC4638137.
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Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR. PLoS One. 2015; 10(10):e0139510. de Oliveira MF, Gianella S, Letendre S, Scheffler K, Kosakovsky Pond SL, Smith DM, Strain M, Ellis RJ. PMID: 26431315; PMCID: PMC4592012.
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Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection. J Neurovirol. 2016 Apr; 22(2):191-200. Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TR, Ramirez-Gaona M, Suben JD, Murrell B, Massanella M, Cherner M, Smith DM, Ellis RJ, Letendre SL, Mehta SR. PMID: 26428514; PMCID: PMC4862614.
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HIV migration between blood plasma and cellular subsets before and after HIV therapy. J Med Virol. 2016 Apr; 88(4):606-13. Choi JY, Chaillon A, Oh JO, Ahn JY, Ann HW, Jung IY, Ahn MY, Jeon YD, Ku NS, Smith DM, Kim JM. PMID: 26348372; PMCID: PMC4731240.
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Repeat HIV-testing is associated with an increase in behavioral risk among men who have sex with men: a cohort study. BMC Med. 2015 Sep 11; 13:218. Hoenigl M, Anderson CM, Green N, Mehta SR, Smith DM, Little SJ. PMID: 26444673; PMCID: PMC4596465.
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Medication persistence and discontinuation of rivaroxaban and dabigatran etexilate among patients with non-valvular atrial fibrillation. Curr Med Res Opin. 2015; 31(10):1831-40. Nelson WW, Song X, Thomson E, Smith DM, Coleman CI, Damaraju CV, Schein JR. PMID: 26211816.
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Subtype associations with HIV-associated neurocognitive disorder in China. J Neurovirol. 2016 Apr; 22(2):246-50. Day TR, Smith DM, Heaton RK, Franklin D, Tilghman MW, Letendre S, Jin H, Wu Z, Shi C, Yu X, Pérez-Santiago J. PMID: 26306690; PMCID: PMC4769127.
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Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Sci Rep. 2015 Aug 24; 5:13179. Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. PMID: 26299251; PMCID: PMC4547398.
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Relativistic electron avalanches as a thunderstorm discharge competing with lightning. Nat Commun. 2015 Aug 12; 6:7845. Kelley NA, Smith DM, Dwyer JR, Splitt M, Lazarus S, Martinez-McKinney F, Hazelton B, Grefenstette B, Lowell A, Rassoul HK. PMID: 26263880.
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What Can We Learn From Measles? No New HIV Infections. Top Antivir Med. 2015 Aug-Sep; 23(3):108-10. Smith DM. PMID: 26518393; PMCID: PMC6148931.
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The need for treatment interruption studies and biomarker identification in the search for an HIV cure. AIDS. 2015 Jul 31; 29(12):1429-32. Li JZ, Smith DM, Mellors JW. PMID: 25870989; PMCID: PMC4529360.
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HIV Transmission Networks in the San Diego-Tijuana Border Region. EBioMedicine. 2015 Oct; 2(10):1456-63. Mehta SR, Wertheim JO, Brouwer KC, Wagner KD, Chaillon A, Strathdee S, Patterson TL, Rangel MG, Vargas M, Murrell B, Garfein R, Little SJ, Smith DM. PMID: 26629540; PMCID: PMC4634195.
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Seminal Shedding of CMV and HIV Transmission among Men Who Have Sex with Men. Int J Environ Res Public Health. 2015 Jul 07; 12(7):7585-92. Gianella S, Scheffler K, Mehta SR, Little SJ, Freitas L, Morris SR, Smith DM. PMID: 26198239; PMCID: PMC4515676.
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Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells. Peptides. 2016 03; 77:16-20. Hodge D, Glass LL, Diakogiannaki E, Pais R, Lenaghan C, Smith DM, Wedin M, Bohlooly-Y M, Gribble FM, Reimann F. PMID: 26144594; PMCID: PMC4788502.
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Targeting HIV Prevention Based on Molecular Epidemiology Among Deeply Sampled Subnetworks of Men Who Have Sex With Men. Clin Infect Dis. 2015 Nov 01; 61(9):1462-8. Wang X, Wu Y, Mao L, Xia W, Zhang W, Dai L, Mehta SR, Wertheim JO, Dong X, Zhang T, Wu H, Smith DM. PMID: 26129754; PMCID: PMC4599390.
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Genital Cytomegalovirus Replication Predicts Syphilis Acquisition among HIV-1 Infected Men Who Have Sex with Men. PLoS One. 2015; 10(6):e0130410. Gianella S, Smith DM, Daar ES, Dube MP, Lisco A, Vanpouille C, Margolis L, Haubrich RH, Morris SR. PMID: 26061824; PMCID: PMC4465639.
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Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis. PLoS Med. 2015 Jun; 12(6):e1001845. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Kee PN, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. PMID: 26030872; PMCID: PMC4452696.
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Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection. Mucosal Immunol. 2016 Jan; 9(1):24-37. Dillon SM, Lee EJ, Kotter CV, Austin GL, Gianella S, Siewe B, Smith DM, Landay AL, McManus MC, Robertson CE, Frank DN, McCarter MD, Wilson CC. PMID: 25921339; PMCID: PMC4626441.
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Differences in Evolution of HIV-1 Subtype C Reverse Transcriptase Between Children and Adults Likely Explained by Maturity of Cytotoxic T-Lymphocyte Responses. AIDS Res Hum Retroviruses. 2015 Jun; 31(6):655-7. Saravanan S, Gomathi S, Kausalya B, Boobalan J, Murugavel KG, Balakrishnan P, Mothi SN, Solomon SS, Kumarasamy N, Selvamuthu P, Solomon S, Smith DM. PMID: 25839730; PMCID: PMC4458742.
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Short Communication: Increase of HIV-1 K103N Transmitted Drug Resistance and Its Association with Efavirenz Use in South Korea. AIDS Res Hum Retroviruses. 2015 Jun; 31(6):603-7. Chin BS, Shin HS, Kim G, Wagner GA, Gianella S, Smith DM. PMID: 25826122; PMCID: PMC4516954.
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Development and validation of the San Diego Early Test Score to predict acute and early HIV infection risk in men who have sex with men. Clin Infect Dis. 2015 Aug 01; 61(3):468-75. Hoenigl M, Weibel N, Mehta SR, Anderson CM, Jenks J, Green N, Gianella S, Smith DM, Little SJ. PMID: 25904374; PMCID: PMC4542926.
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Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis. PLoS Med. 2015 Apr; 12(4):e1001810. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, Rinke de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Ng KP, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. PMID: 25849352; PMCID: PMC4388826.
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The Sordid Affair Between Human Herpesvirus and HIV. J Infect Dis. 2015 Sep 15; 212(6):845-52. Gianella S, Massanella M, Wertheim JO, Smith DM. PMID: 25748324; PMCID: PMC4548466.
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Measuring vaccine confidence: introducing a global vaccine confidence index. PLoS Curr. 2015 Feb 25; 7. Larson HJ, Schulz WS, Tucker JD, Smith DM. PMID: 25789200; PMCID: PMC4353663.
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Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection. Mol Biol Evol. 2015 May; 32(5):1342-53. Smith MD, Wertheim JO, Weaver S, Murrell B, Scheffler K, Kosakovsky Pond SL. PMID: 25697341; PMCID: PMC4408413.
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Gene-wide identification of episodic selection. Mol Biol Evol. 2015 May; 32(5):1365-71. Murrell B, Weaver S, Smith MD, Wertheim JO, Murrell S, Aylward A, Eren K, Pollner T, Martin DP, Smith DM, Scheffler K, Kosakovsky Pond SL. PMID: 25701167; PMCID: PMC4408417.
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Reply to Haddow et al. Clin Infect Dis. 2015 May 01; 60(9):1442-3. Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I, CHARTER Group. PMID: 25645217; PMCID: PMC4415055.
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Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals. JAMA Intern Med. 2015 Jan; 175(1):88-99. Okulicz JF, Le TD, Agan BK, Camargo JF, Landrum ML, Wright E, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. PMID: 25419650; PMCID: PMC4286496.
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The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120. PLoS One. 2014; 9(12):e114942. Bjursell M, Xu X, Admyre T, Böttcher G, Lundin S, Nilsson R, Stone VM, Morgan NG, Lam YY, Storlien LH, Lindén D, Smith DM, Bohlooly-Y M, Oscarsson J. PMID: 25541716; PMCID: PMC4277291.
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Hepatitis B virus compartmentalization in the cerebrospinal fluid of HIV-infected patients. Clin Microbiol Infect. 2015 Apr; 21(4):387.e5-8. Ene L, Duiculescu D, Tardei G, Ruta S, Smith DM, Mehta S, Letendre S, Achim CL. PMID: 25658525; PMCID: PMC4424164.
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Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure. J Clin Virol. 2015 Jan; 62:48-53. Fisher RG, Smith DM, Murrell B, Slabbert R, Kirby BM, Edson C, Cotton MF, Haubrich RH, Kosakovsky Pond SL, Van Zyl GU. PMID: 25542470; PMCID: PMC4279108.
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HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing. Virology. 2015 Jan 01; 474:34-40. Carter CC, Wagner GA, Hightower GK, Caballero G, Phung P, Richman DD, Pond SL, Smith DM. PMID: 25463602; PMCID: PMC4259848.
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Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study. Clin Infect Dis. 2015 Feb 01; 60(3):473-80. Heaton RK, Franklin DR, Deutsch R, Letendre S, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst AC, Fennema-Notestine C, Smith DM, Grant I, CHARTER Group. PMID: 25362201; PMCID: PMC4303775.
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IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. PLoS Comput Biol. 2014 Sep; 10(9):e1003842. Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. PMID: 25254639; PMCID: PMC4177671.
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Pre-exposure prophylaxis accessibility research and evaluation (PrEPARE Study). AIDS Behav. 2014 Sep; 18(9):1722-5. King HL, Keller SB, Giancola MA, Rodriguez DA, Chau JJ, Young JA, Little SJ, Smith DM. PMID: 25017425; PMCID: PMC4127131.
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Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence. PLoS One. 2014; 9(7):e102555. Desplats P, Dumaop W, Cronin P, Gianella S, Woods S, Letendre S, Smith D, Masliah E, Grant I. PMID: 25054922; PMCID: PMC4108358.
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Cerebrospinal fluid can be used for HIV genotyping when it fails in blood. Arq Neuropsiquiatr. 2014 Jul; 72(7):506-9. Rotta I, Raboni SM, Ribeiro CE, Riedel M, Winhescki Mda G, Smith DM, Ellis RJ, de Almeida SM. PMID: 25054982; PMCID: PMC4139176.
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Evolutionary origins of human herpes simplex viruses 1 and 2. Mol Biol Evol. 2014 Sep; 31(9):2356-64. Wertheim JO, Smith MD, Smith DM, Scheffler K, Kosakovsky Pond SL. PMID: 24916030; PMCID: PMC4137711.
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Antigen-presenting phagocytic cells ingest malaria parasites and increase HIV replication in a tumor necrosis factor α-dependent manner. J Infect Dis. 2014 Nov 15; 210(10):1562-72. Orlov M, Vaida F, Williamson K, Deng Q, Smith DM, Duffy PE, Schooley RT. PMID: 24903666; PMCID: PMC4215075.
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Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients. AIDS Res Hum Retroviruses. 2014 Aug; 30(8):827-9. Jeong SJ, Kim MH, Song JE, Ahn JY, Kim SB, Ann HW, Kim JK, Choi H, Ku NS, Han SH, Kim JM, Smith DM, Kim HS, Choi JY. PMID: 24724838; PMCID: PMC4118713.
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Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology. 2014 Jun 10; 82(23):2055-62. Grant I, Franklin DR, Deutsch R, Woods SP, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Heaton RK, CHARTER Group. PMID: 24814848; PMCID: PMC4118496.
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Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. J Virol. 2014 Jul; 88(14):7818-27. Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM, California Collaborative Treatment Group 592 Team. PMID: 24789781; PMCID: PMC4097769.
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Mathematical modeling of HIV prevention measures including pre-exposure prophylaxis on HIV incidence in South Korea. PLoS One. 2014; 9(3):e90080. Kim SB, Yoon M, Ku NS, Kim MH, Song JE, Ahn JY, Jeong SJ, Kim C, Kwon HD, Lee J, Smith DM, Choi JY. PMID: 24662776; PMCID: PMC3963840.
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HIV-associated neurocognitive disorder in HIV-infected Koreans: the Korean NeuroAIDS Project. HIV Med. 2014 Sep; 15(8):470-7. Ku NS, Lee Y, Ahn JY, Song JE, Kim MH, Kim SB, Jeong SJ, Hong KW, Kim E, Han SH, Song JY, Cheong HJ, Song YG, Kim WJ, Kim JM, Smith DM, Choi JY. PMID: 24580888; PMCID: PMC4140963.
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Community HIV-1 drug resistance is associated with transmitted drug resistance. HIV Med. 2014 Jul; 15(6):339-46. Tilghman MW, Pérez-Santiago J, Osorio G, Little SJ, Richman DD, Mathews WC, Haubrich RH, Smith DM. PMID: 24417811; PMCID: PMC4055747.
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An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. Mucosal Immunol. 2014 Jul; 7(4):983-94. Dillon SM, Lee EJ, Kotter CV, Austin GL, Dong Z, Hecht DK, Gianella S, Siewe B, Smith DM, Landay AL, Robertson CE, Frank DN, Wilson CC. PMID: 24399150; PMCID: PMC4062575.
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Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress response. Exp Physiol. 2014 Mar; 99(3):538-51. Mullooly N, Vernon W, Smith DM, Newsholme P. PMID: 24334335.
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Strengthening research capacity through the medical education partnership initiative: the Mozambique experience. Hum Resour Health. 2013 Dec 05; 11:62. Noormahomed EV, Mocumbi AO, Preziosi M, Damasceno A, Bickler S, Smith DM, Funzamo C, Aronoff-Spencer E, Badaró R, Mabila F, Bila D, Nguenha A, Do Rosário V, Benson CA, Schooley RT, Patel S, Ferrão LJ, Carrilho C. PMID: 24304706; PMCID: PMC3895849.
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Neurocognitive impairment in HIV-1 clade C- versus B-infected individuals in Southern Brazil. J Neurovirol. 2013 Dec; 19(6):550-6. de Almeida SM, Ribeiro CE, de Pereira AP, Badiee J, Cherner M, Smith D, Maich I, Raboni SM, Rotta I, Barbosa FJ, Heaton RK, Umlauf A, Ellis RJ. PMID: 24277437; PMCID: PMC3923762.
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Real-world impact of neurocognitive deficits in acute and early HIV infection. J Neurovirol. 2013 Dec; 19(6):565-73. Doyle KL, Morgan EE, Morris S, Smith DM, Little S, Iudicello JE, Blackstone K, Moore DJ, Grant I, Letendre SL, Woods SP, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 24277439; PMCID: PMC3865175.
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Pooled nucleic acid testing to identify antiretroviral treatment failure during HIV infection in Seoul, South Korea. Scand J Infect Dis. 2014 Feb; 46(2):136-40. Kim SB, Kim HW, Kim HS, Ann HW, Kim JK, Choi H, Kim MH, Song JE, Ahn JY, Ku NS, Oh DH, Kim YC, Jeong SJ, Han SH, Kim JM, Smith DM, Choi JY. PMID: 24228824; PMCID: PMC3894056.
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Antibody response to Achromobacter xylosoxidans during HIV infection is associated with lower CD4 levels and increased lymphocyte activation. Clin Vaccine Immunol. 2014 Jan; 21(1):46-50. Tatro ET, Purnajo I, Richman DD, Smith DM, Gianella S. PMID: 24173027; PMCID: PMC3910916.
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Genetic attributes of blood-derived subtype-C HIV-1 tat and env in India and neurocognitive function. J Med Virol. 2014 Jan; 86(1):88-96. Tilghman MW, Bhattacharya J, Deshpande S, Ghate M, Espitia S, Grant I, Marcotte TD, Smith D, Mehendale S. PMID: 24150902; PMCID: PMC3872113.
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The global transmission network of HIV-1. J Infect Dis. 2014 Jan 15; 209(2):304-13. Wertheim JO, Leigh Brown AJ, Hepler NL, Mehta SR, Richman DD, Smith DM, Kosakovsky Pond SL. PMID: 24151309; PMCID: PMC3873788.
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Novel codon insert in HIV type 1 clade B reverse transcriptase associated with low-level viremia during antiretroviral therapy. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):165-9. Chaillon A, Gianella S, Vazquez H, Ignacio C, Zweig AC, Richman DD, Smith DM. PMID: 24020934; PMCID: PMC3910474.
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Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection. J Virol. 2013 Dec; 87(23):12737-44. Chaillon A, Wagner GA, Hepler NL, Little SJ, Kosakovsky Pond SL, Caballero G, Pacold ME, Phung P, Wrin T, Richman DD, Wertheim JO, Smith DM. PMID: 24049166; PMCID: PMC3838120.
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Food-induced anaphylaxis among commercially insured US adults: patient concordance with postdischarge care guidelines. J Allergy Clin Immunol Pract. 2013 Nov-Dec; 1(6):595-601.e1. Landsman-Blumberg PB, Wei W, Douglas D, Smith DM, Clark S, Camargo CA. PMID: 24565706.
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Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. AIDS. 2013 Jul 31; 27(12):1921-31. Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM. PMID: 24180001; PMCID: PMC3816380.
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Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine. J Infect Dis. 2013 Jun 15; 207 Suppl 2:S70-7. Tang MW, Rhee SY, Bertagnolio S, Ford N, Holmes S, Sigaloff KC, Hamers RL, de Wit TF, Fleury HJ, Kanki PJ, Ruxrungtham K, Hawkins CA, Wallis CL, Stevens W, van Zyl GU, Manosuthi W, Hosseinipour MC, Ngo-Giang-Huong N, Belec L, Peeters M, Aghokeng A, Bunupuradah T, Burda S, Cane P, Cappelli G, Charpentier C, Dagnra AY, Deshpande AK, El-Katib Z, Eshleman SH, Fokam J, Gody JC, Katzenstein D, Koyalta DD, Kumwenda JJ, Lallemant M, Lynen L, Marconi VC, Margot NA, Moussa S, Ndung'u T, Nyambi PN, Orrell C, Schapiro JM, Schuurman R, Sirivichayakul S, Smith D, Zolfo M, Jordan MR, Shafer RW. PMID: 23687292; PMCID: PMC3657117.
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High prevalence of hepatitis delta virus among patients with chronic hepatitis B virus infection and HIV-1 in an intermediate hepatitis B virus endemic region. J Int Assoc Provid AIDS Care. 2014 Jan-Feb; 13(1):85-90. Saravanan S, Madhavan V, Velu V, Murugavel KG, Waldrop G, Solomon SS, Balakrishnan P, Kumarasamy N, Smith DM, Mayer KH, Solomon S, Thyagarajan SP. PMID: 23722085; PMCID: PMC4114572.
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Reply to Mounzer and DiNubile. J Infect Dis. 2013 Aug 15; 208(4):711-2. Morris SR, Smith DM, Little SJ, Gianella S. PMID: 23667136; PMCID: PMC3719903.
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Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men. Clin Infect Dis. 2013 Aug; 57(3):441-7. Gianella S, Smith DM, Vargas MV, Little SJ, Richman DD, Daar ES, Dube MP, Zhang F, Ginocchio CC, Haubrich RH, Morris SR, CCTG 592 Team. PMID: 23595831; PMCID: PMC3703105.
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Simulation of pooled nucleic acid testing to identify antiretroviral treatment failure during HIV infection in Seoul, South Korea. J Acquir Immune Defic Syndr. 2013 Mar 01; 62(3):e104-5. Kim H, Ku NS, Kim SB, Jeong SJ, Han SH, Kim JM, Smith DM, Choi JY. PMID: 23924640; PMCID: PMC3873092.
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Apolipoprotein E4 genotype does not increase risk of HIV-associated neurocognitive disorders. J Neurovirol. 2013 Apr; 19(2):150-6. Morgan EE, Woods SP, Letendre SL, Franklin DR, Bloss C, Goate A, Heaton RK, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Ellis RJ, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I, Vaida F, Clifford DB, CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Group. PMID: 23408335; PMCID: PMC3668779.
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Cytokines in CSF correlate with HIV-associated neurocognitive disorders in the post-HAART era in China. J Neurovirol. 2013 Apr; 19(2):144-9. Yuan L, Qiao L, Wei F, Yin J, Liu L, Ji Y, Smith D, Li N, Chen D. PMID: 23389619; PMCID: PMC4363104.
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Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. N Engl J Med. 2013 Jan 17; 368(3):218-30. Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. PMID: 23323898; PMCID: PMC3657555.
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Phylogenetic relatedness of HIV-1 donor and recipient populations. J Infect Dis. 2013 Apr; 207(7):1181-2. Wertheim JO, Scheffler K, Choi JY, Smith DM, Kosakovsky Pond SL. PMID: 23315327; PMCID: PMC3583277.
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Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract. AIDS. 2013 Jan 02; 27(1):39-47. Gianella S, Morris SR, Anderson C, Spina CA, Vargas MV, Young JA, Richman DD, Little SJ, Smith DM. PMID: 22739399; PMCID: PMC3769229.
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Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. J Infect Dis. 2013 Mar 15; 207(6):898-902. Gianella S, Anderson CM, Vargas MV, Richman DD, Little SJ, Morris SR, Smith DM. PMID: 23275608; PMCID: PMC3571441.
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Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection. Clin Infect Dis. 2013 Apr; 56(7):1038-43. Fierer DS, Dieterich DT, Fiel MI, Branch AD, Marks KM, Fusco DN, Hsu R, Smith DM, Fierer J. PMID: 23264364; PMCID: PMC3588118.
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Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection. J Neurovirol. 2013 Feb; 19(1):65-74. Weber E, Morgan EE, Iudicello JE, Blackstone K, Grant I, Ellis RJ, Letendre SL, Little S, Morris S, Smith DM, Moore DJ, Woods SP, TMARC Group. PMID: 23250704; PMCID: PMC3568179.
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Darunavir is a good third-line antiretroviral agent for HIV type 1-infected patients failing second-line protease inhibitor-based regimens in South India. AIDS Res Hum Retroviruses. 2013 Mar; 29(3):630-2. Saravanan S, Madhavan V, Balakrishnan P, Smith DM, Solomon SS, Sivamalar S, Poongulali S, Kumarasamy N, Schooley RT, Solomon S, Kantor R. PMID: 23045961; PMCID: PMC3581023.
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Role of seminal shedding of herpesviruses in HIV Type 1 Transmission. J Infect Dis. 2013 Jan 15; 207(2):257-61. Gianella S, Morris SR, Vargas MV, Young JA, Callahan B, Richman DD, Little SJ, Smith DM. PMID: 23148284; PMCID: PMC3532824.
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P. falciparum enhances HIV replication in an experimental malaria challenge system. PLoS One. 2012; 7(6):e39000. Orlov M, Vaida F, Finney OC, Smith DM, Talley AK, Wang R, Kappe SH, Deng Q, Schooley RT, Duffy PE. PMID: 22745697; PMCID: PMC3383717.
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Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry. EMBO J. 2011 Jul 08; 30(15):3065-77. Deriziotis P, André R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH, Collinge J, Goldberg AL, Tabrizi SJ. PMID: 21743439; PMCID: PMC3160194.
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ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell. 2011 Feb 18; 144(4):526-38. Smith DM, Fraga H, Reis C, Kafri G, Goldberg AL. PMID: 21335235; PMCID: PMC3063399.
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A compound QM/MM procedure: comparative performance on a pyruvate formate-lyase model system. J Comput Chem. 2010 Apr 15; 31(5):1024-35. Condic-Jurkic K, Zipse H, Smith DM. PMID: 19847785.
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On the importance of ribose orientation in the substrate activation of the coenzyme B12-dependent mutases. Chemistry. 2009 Aug 24; 15(34):8578-8585. Durbeej B, Sandala GM, Bucher D, Smith DM, Radom L. PMID: 19630017.
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Differences in tuberculin reactivity as determined in a veterans administration employee health screening program. Clin Vaccine Immunol. 2009 Apr; 16(4):541-3. Mehta SR, MacGruder C, Looney D, Johns S, Smith DM. PMID: 19225075; PMCID: PMC2668276.
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A public health model for the molecular surveillance of HIV transmission in San Diego, California. AIDS. 2009 Jan 14; 23(2):225-32. Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. PMID: 19098493; PMCID: PMC2644048.
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Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 2009 Mar 01; 385(1):204-8. Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ, HNRC Group. PMID: 19100592; PMCID: PMC2794037.
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Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men. AIDS. 2008 Aug 20; 22(13):1667-71. Butler DM, Smith DM, Cachay ER, Hightower GK, Nugent CT, Richman DD, Little SJ. PMID: 18670228; PMCID: PMC2653089.
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Running with scissors: using antiretroviral therapy without monitoring viral load. Clin Infect Dis. 2008 May 15; 46(10):1598-600. Smith DM, Schooley RT. PMID: 18419496.
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Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. AIDS. 2008 Apr 23; 22(7):835-9. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. PMID: 18427201; PMCID: PMC2716722.
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Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. J Virol. 2008 Jun; 82(11):5510-8. Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. PMID: 18353964; PMCID: PMC2395184.
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Active duty military personnel presenting for care at a Gay Men's Health Clinic. J Homosex. 2008; 54(3):277-9. Smith DM. PMID: 18825864.
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Active methamphetamine use is associated with transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors in individuals with HIV infection of unknown duration. Open AIDS J. 2007; 1:5-10. Cachay ER, Moini N, Kosakovsky Pond SL, Pesano R, Lie YS, Aiem H, Butler DM, Letendre S, Mathews WC, Smith DM. PMID: 18923691; PMCID: PMC2556194.
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Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis. 2007 Aug 01; 196(3):356-60. Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. PMID: 17597449.
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Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. J Infect Dis. 2007 May 01; 195(9):1270-7. Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. PMID: 17396995.
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Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1. J Virol. 2007 May; 81(9):4776-86. Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC. PMID: 17329339; PMCID: PMC1900175.
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Physicians' attitudes toward homosexuality and HIV: survey of a California Medical Society- revisited (PATHH-II). J Homosex. 2007; 52(3-4):1-9. Smith DM, Mathews WC. PMID: 17594969.
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Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 2006 Nov 10; 355(1):1-5. Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. PMID: 16962152.
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Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain. 2006 Jul; 129(Pt 7):1872-83. Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. PMID: 16735456.
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Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J Infect Dis. 2006 Jul 01; 194(1):29-37. Goicoechea M, Smith DM, Liu L, May S, Tenorio AR, Ignacio CC, Landay A, Haubrich R. PMID: 16741879.
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The controversies of nevirapine for preventing mother-to-child HIV transmission. AIDS. 2006 Jan 09; 20(2):281-3. Smith DM. PMID: 16511423.
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Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18514-9. Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. PMID: 16339909; PMCID: PMC1310509.
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HIV drug resistance acquired through superinfection. AIDS. 2005 Aug 12; 19(12):1251-6. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. PMID: 16052079.
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Naturally occurring proteasome inhibitors from mate tea (Ilex paraguayensis) serve as models for topical proteasome inhibitors. J Invest Dermatol. 2005 Aug; 125(2):207-12. Arbiser JL, Li XC, Hossain CF, Nagle DG, Smith DM, Miller P, Govindarajan B, DiCarlo J, Landis-Piwowar KR, Dou QP. PMID: 16098028.
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HIV treatment decisions and transmitted drug resistance. Clin Infect Dis. 2005 Jul 15; 41(2):233-5. Little SJ, Smith DM. PMID: 15983921.
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Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol. 2005 Feb; 79(3):1772-88. Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. PMID: 15650202; PMCID: PMC544082.
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Semen-specific genetic characteristics of human immunodeficiency virus type 1 env. J Virol. 2005 Feb; 79(3):1734-42. Pillai SK, Good B, Pond SK, Wong JK, Strain MC, Richman DD, Smith DM. PMID: 15650198; PMCID: PMC544119.
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Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. J Virol. 2005 Jan; 79(2):860-8. Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. PMID: 15613314; PMCID: PMC538553.
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Fornix lesions impair context-related cingulothalamic neuronal patterns and concurrent discrimination learning in rabbits (Oryctolagus cuniculus). Behav Neurosci. 2004 Dec; 118(6):1225-39. Smith DM, Wakeman D, Patel J, Gabriel M. PMID: 15598132.
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The prostate as a reservoir for HIV-1. AIDS. 2004 Jul 23; 18(11):1600-2. Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. PMID: 15238781.
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Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS. 2003 May 02; 17(7):F11-6. Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Brown AJ, Petropoulos CJ, Richman DD, Wong JK. PMID: 12700477.
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Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4819-24. Strain MC, Günthard HF, Havlir DV, Ignacio CC, Smith DM, Leigh-Brown AJ, Macaranas TR, Lam RY, Daly OA, Fischer M, Opravil M, Levine H, Bacheler L, Spina CA, Richman DD, Wong JK. PMID: 12684537; PMCID: PMC153639.
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Continue antiretroviral therapy during virologic failure? Clin Infect Dis. 2002 Feb 15; 34(4):553-6. Smith D, Wong J. PMID: 11797186.
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Viral pneumonia as a serious complication of etanercept therapy. Ann Intern Med. 2002 Jan 15; 136(2):174. Smith D, Letendre S. PMID: 11790076.
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