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A Humanized Lym-1 CAR with Novel DAP10/DAP12 Signaling Domains Demonstrates Reduced Tonic Signaling and Increased Antitumor Activity in B-Cell Lymphoma Models. Clin Cancer Res. 2020 07 15; 26(14):3694-3706. Zheng L, Ren L, Kouhi A, Khawli LA, Hu P, Kaslow HR, Epstein AL. PMID: 32273277.
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Lym-1 Chimeric Antigen Receptor T Cells Exhibit Potent Anti-Tumor Effects against B-Cell Lymphoma. Int J Mol Sci. 2017 Dec 20; 18(12). Zheng L, Hu P, Wolfe B, Gonsalves C, Ren L, Khawli LA, Kaslow HR, Epstein AL. PMID: 29261129; PMCID: PMC5751371.
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P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide. J Immunol. 2005 Feb 15; 174(4):1971-9. Kawamura H, Aswad F, Minagawa M, Malone K, Kaslow H, Koch-Nolte F, Schott WH, Leiter EH, Dennert G. PMID: 15699125.
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Expression of IL-10 and TNF-inhibitor genes in lacrimal gland epithelial cells suppresses their ability to activate lymphocytes. Cornea. 2002 Mar; 21(2):210-4. Zhu Z, Stevenson D, Ritter T, Schechter JE, Mircheff AK, Kaslow HR, Trousdale MD. PMID: 11862098.
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Effect of anti-inflammatory cytokines on the activation of lymphocytes by lacrimal gland acinar cells in an autologous mixed cell reaction. Adv Exp Med Biol. 2002; 506(Pt B):789-94. Trousdale MD, Stevenson D, Zhu Z, Kaslow HR, Schechter JE, Warren DW, Azzarolo AM, Ritter T, Mircheff AK. PMID: 12613993.
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Autologous lacrimal-lymphoid mixed-cell reactions induce dacryoadenitis in rabbits. Exp Eye Res. 2000 Jul; 71(1):23-31. Guo Z, Song D, Azzarolo AM, Schechter JE, Warren DW, Wood RL, Mircheff AK, Kaslow HR. PMID: 10880273.
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Lacrimal gland epithelial cells stimulate proliferation in autologous lymphocyte preparations. Exp Eye Res. 2000 Jul; 71(1):11-22. Guo Z, Azzarolo AM, Schechter JE, Warren DW, Wood RL, Mircheff AK, Kaslow HR. PMID: 10880272.
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A method to study induction of autoimmunity in vitro: co-culture of lacrimal cells and autologous immune system cells. Adv Exp Med Biol. 1998; 438:583-9. Kaslow HR, Guo Z, Warren DW, Wood RL, Mircheff AK. PMID: 9634940.
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Sjögren's autoimmunity: how perturbation of recognition in endomembrane traffic may provoke pathological recognition at the cell surface. J Mol Recognit. 1998; 11(1-6):40-8. Mircheff AK, Gierow JP, Yang T, Zhang J, Wood RL, Azzarolo AM, Warren DW, Zeng H, Guo Z, Kaslow HR, Hamm-Alvarez SF, Okamoto CT, Bachmann M. PMID: 10076804.
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Authors and Editors of the world unite. FASEB J. 1995 Feb; 9(2):291. Kaslow HR. PMID: 7781934.
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Molecular engineering of cholera toxin. Adv Exp Med Biol. 1995; 371B:1513-8. Burnette WN, Kaslow HR, Moss J. PMID: 7502847.
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Regulation of cytotoxic T cells by ecto-nicotinamide adenine dinucleotide (NAD) correlates with cell surface GPI-anchored/arginine ADP-ribosyltransferase. J Immunol. 1994 Nov 01; 153(9):4048-58. Wang J, Nemoto E, Kots AY, Kaslow HR, Dennert G. PMID: 7930612.
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Construction and characterization of recombinant Vibrio cholerae strains producing inactive cholera toxin analogs. Infect Immun. 1994 Aug; 62(8):3051-7. Häse CC, Thai LS, Boesman-Finkelstein M, Mar VL, Burnette WN, Kaslow HR, Stevens LA, Moss J, Finkelstein RA. PMID: 8039872; PMCID: PMC302926.
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Recombinant microbial ADP-ribosylating toxins of Bordetella pertussis, Vibrio cholerae, and enterotoxigenic Escherichia coli: structure, function, and toxoid vaccine development. Bioprocess Technol. 1994; 19:185-203. Burnette WN, Cieplak W, Kaslow HR, Rappuoli R, Tuomanen EI. PMID: 7764758.
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CTX-B inhibits CTL cytotoxicity and cytoskeletal movements. Immunopharmacology. 1993 Sep-Oct; 26(2):93-104. Sugawara S, Kaslow HR, Dennert G. PMID: 8282542.
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Pertussis toxin and target eukaryotic cells: binding, entry, and activation. FASEB J. 1992 Jun; 6(9):2684-90. Kaslow HR, Burns DL. PMID: 1612292.
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Detection of antibodies inhibiting the ADP-ribosyltransferase activity of pertussis toxin in human serum. J Clin Microbiol. 1992 Jun; 30(6):1380-7. Kaslow HR, Platler BW, Blumberg DA, Cherry JD. PMID: 1624552; PMCID: PMC265296.
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Site-specific mutagenesis of the catalytic subunit of cholera toxin: substituting lysine for arginine 7 causes loss of activity. Infect Immun. 1991 Nov; 59(11):4266-70. Burnette WN, Mar VL, Platler BW, Schlotterbeck JD, McGinley MD, Stoney KS, Rohde MF, Kaslow HR. PMID: 1937784; PMCID: PMC259028.
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Monoclonal antibodies against the enzymatic subunit of both pertussis and cholera toxins. Dev Biol Stand. 1991; 73:133-41. Kenimer JG, Probst PG, Karpas AB, Burns DL, Kaslow HR. PMID: 1778307.
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Evaluation of antibodies elicited by immunization with pertussis toxin. Dev Biol Stand. 1991; 73:143-50. Kaslow HR, Schlotterbeck JD, Gotto J. PMID: 1778308.
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The molecular engineering of pertussis toxoid. Dev Biol Stand. 1991; 73:75-8. Burnette WN, Mar VL, Bartley TD, Kaslow HR, Cieplak W, Keith JM, Sato H, Burns DL, Arciniega JL, Shahin RD, et al. PMID: 1778336.
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Monoclonal antibodies that inhibit ADP-ribosyltransferase but not NAD-glycohydrolase activity of pertussis toxin. Infect Immun. 1990 Mar; 58(3):746-52. Kaslow HR, Schlotterbeck JD, Kenimer JG. PMID: 2155182; PMCID: PMC258528.
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Radiometric assays for glycerol, glucose, and glycogen. Anal Biochem. 1989 Jul; 180(1):11-6. Bradley DC, Kaslow HR. PMID: 2817333.
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Alkylation of cysteine 41, but not cysteine 200, decreases the ADP-ribosyltransferase activity of the S1 subunit of pertussis toxin. J Biol Chem. 1989 Apr 15; 264(11):6386-90. Kaslow HR, Schlotterbeck JD, Mar VL, Burnette WN. PMID: 2703495.
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Developments toward a recombinant pertussis vaccine. Adv Exp Med Biol. 1989; 251:1-7. Burnette WN, Whiteley DW, Mar VL, Burns DL, Kaslow HR, Cieplak W, Keith JM, Bartley TD. PMID: 2692423.
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Regulation of glycogen synthase in muscle and adipose tissue during fasting and refeeding. Am J Physiol. 1988 Jun; 254(6 Pt 1):E720-5. Antwi D, Youn JH, Shargill NS, Lesikar DD, Kaslow HR. PMID: 3132046.
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Fructose effect to suppress hepatic glycogen degradation. J Biol Chem. 1987 Aug 25; 262(24):11470-7. Youn JH, Kaslow HR, Bergman RN. PMID: 3114246.
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Sulfhydryl-alkylating reagents inactivate the NAD glycohydrolase activity of pertussis toxin. Biochemistry. 1987 Jul 14; 26(14):4397-402. Kaslow HR, Lesikar DD. PMID: 2822091.
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Structure-activity analysis of the activation of pertussis toxin. Biochemistry. 1987 Jan 13; 26(1):123-7. Kaslow HR, Lim LK, Moss J, Lesikar DD. PMID: 3030399.
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Stimulation of the thiol-dependent ADP-ribosyltransferase and NAD glycohydrolase activities of Bordetella pertussis toxin by adenine nucleotides, phospholipids, and detergents. Biochemistry. 1986 May 06; 25(9):2720-5. Moss J, Stanley SJ, Watkins PA, Burns DL, Manclark CR, Kaslow HR, Hewlett EL. PMID: 2872921.
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L-type glycogen synthase. Tissue distribution and electrophoretic mobility. J Biol Chem. 1985 Aug 25; 260(18):9953-6. Kaslow HR, Lesikar DD, Antwi D, Tan AW. PMID: 3926776.
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Adenine nucleotides directly stimulate pertussis toxin. J Biol Chem. 1985 Mar 10; 260(5):2585-8. Lim LK, Sekura RD, Kaslow HR. PMID: 2982826.
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Fasting and diabetes alter adipose tissue glycogen synthase. Am J Physiol. 1984 Nov; 247(5 Pt 1):E581-4. Kaslow HR, Eichner RD. PMID: 6437248.
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Isozymes of glycogen synthase. FEBS Lett. 1984 Jul 09; 172(2):294-8. Kaslow HR, Lesikar DD. PMID: 6430719.
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Genetic analysis of cyclic nucleotide phosphodiesterases in S49 mouse lymphoma cells. Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984; 16:185-94. Bourne HR, Brothers VM, Kaslow HR, Groppi V, Walker N, Steinberg F. PMID: 6326523.
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A direct radioassay for pyruvate kinase activity. Anal Biochem. 1983 Oct 15; 134(2):495-8. Kaslow HR, Garrison CR. PMID: 6418026.
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Identification by direct photoaffinity labeling of an altered phosphodiesterase in a mutant S49 lymphoma cell. J Biol Chem. 1983 Aug 25; 258(16):9717-23. Groppi VE, Steinberg F, Kaslow HR, Walker N, Bourne HR. PMID: 6309783.
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Cholera toxin can catalyze ADP-ribosylation of cytoskeletal proteins. J Cell Biol. 1981 Nov; 91(2 Pt 1):410-3. Kaslow HR, Groppi VE, Abood ME, Bourne HR. PMID: 7309789; PMCID: PMC2111969.
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Fibroblast defect in pseudohypoparathyroidism, type I: reduced activity of receptor-cyclase coupling protein. J Clin Endocrinol Metab. 1981 Sep; 53(3):636-40. Bourne HR, Kaslow HR, Brickman AS, Farfel Z. PMID: 6267099.
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Hormone-sensitive adenylate cyclase. Mutant phenotype with normally regulated beta-adrenergic receptors uncoupled with catalytic adenylate cyclase. Mol Pharmacol. 1981 Sep; 20(2):435-41. Bourne HR, Kaslow D, Kaslow HR, Salomon MR, Licko V. PMID: 6272096.
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An Mr = 52,000 peptide can mediate effects on cholera toxin on adenylate cyclase in intact cells. Mol Pharmacol. 1981 May; 19(3):406-10. Kaslow HR, Cox D, Groppi VE, Bourne HR. PMID: 6790933.
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Human mutation affecting hormone-sensitive adenylate cyclase. Prog Clin Biol Res. 1981; 63:433-7. Bourne HR, Farfel Z, Brickman AS, Kaslow HR, Brothers VM. PMID: 6273928.
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Apparent phosphorylation of glycogen synthase in mammalian cells lacking cyclic AMP-dependent protein kinase. FEBS Lett. 1980 Aug 11; 117(1):219-23. Kaslow HR. PMID: 6773808.
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Defect of receptor-cyclase coupling protein in pseudohypoparathyroidism. N Engl J Med. 1980 07 31; 303(5):237-42. Farfel Z, Brickman AS, Kaslow HR, Brothers VM, Bourne HR. PMID: 6247654.
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A regulatory component of adenylate cyclase from human erythrocyte membranes. J Biol Chem. 1980 Apr 25; 255(8):3736-41. Kaslow HR, Johnson GL, Brothers VM, Bourne HR. PMID: 7364766.
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Genetic analysis of hormone-sensitive adenylate cyclase. Adv Cyclic Nucleotide Res. 1980; 13:1-37. Johnson GL, Kaslow HR, Farfel Z, Bourne HR. PMID: 6251703.
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A regulatory component of adenylate cyclase is located on the inner surface of human erythrocyte membranes. Biochem Biophys Res Commun. 1979 Oct 29; 90(4):1237-41. Farfel Z, Kaslow HR, Bourne HR. PMID: 518596.
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Interconversion between multiple glucose 6-phosphate-dependent forms of glycogen synthase in intact adipose tissue. J Biol Chem. 1979 Jun 10; 254(11):4674-7. Kaslow HR, Eichner RD, Mayer SE. PMID: 108279.
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Adaptations of glycogen metabolism in rat epididymal adipose tissue during fasting and refeeding. J Biol Chem. 1979 Jun 10; 254(11):4678-83. Kaslow HR, Mayer SE. PMID: 108280.
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Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate. Mol Pharmacol. 1979 May; 15(3):472-83. Kaslow HR, Farfel Z, Johnson GL, Bourne HR. PMID: 226858.
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Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase. J Biol Chem. 1978 Oct 25; 253(20):7120-3. Johnson GL, Kaslow HR, Bourne HR. PMID: 212417.
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Reconstitution of cholera toxin-activated adenylate cyclase. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3113-7. Johnson GL, Kaslow HR, Bourne HR. PMID: 277913; PMCID: PMC392724.
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Purification of the cAMP receptor protein by affinity chromatography. Biochem Biophys Res Commun. 1974 Jul 24; 59(2):813-21. Ramseyer J, Kaslow HR, Gill GN. PMID: 4369094.
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