Mark A Varvares, MD, FACS (Researcher Profile) | Mass Eye and Ear

Mark A Varvares, MD, FACS (Researcher Profile) |
Mass Eye and Ear
Mark A. Varvares,
MD, FACS
Massachusetts Eye and Ear
Chair, Department of Otolaryngology–Head and Neck Surgery, Mass General Brigham
Harvard Medical School
William W. Montgomery/John W. Merriam Professor and Chair of Otolaryngology–Head and Neck Surgery
Phone:
617-573-3192
Clinician Profile
About My Research
Dr. Mark Varvares conducts a research program in head and neck oncology, studying how surgical pathology of head and neck tumors impact survival. Other research interests include a variety of topics in head and neck reconstruction, the role of oncolytic adenoviruses as a possible therapeutic modality to treat head and neck cancer and the role of music therapy as an intervention in cancer management.
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Prognostic Value of Tumor-Informed Circulating Tumor DNA in HPV-Independent Head and Neck Squamous Cell Carcinoma. JAMA Otolaryngol Head Neck Surg. 2026 Mar 01; 152(3):249-258.
Donor Site Morbidity of Lower Extremity Free Flaps After Reconstructive Surgery of the Head and Neck, a Single-Center Retrospective Cohort Study. Head Neck. 2026 Feb 02.
Prognostic value of tumor-informed ctDNA in HPV-independent head and neck squamous cell carcinoma. medRxiv. 2026 Jan 12.
Incidence of HPV-independent second primary malignancies following treatment of HPV-associated malignancy. Oral Oncol. 2026 Jan; 172:107790.
Clinical validation of an HPV whole genome sequencing assay for molecular residual disease detection in HPV-associated head and neck cancer patients treated with surgery. medRxiv. 2025 Nov 27.
Impact of Margin Assessment Method on Adjuvant Therapy and Recurrence in Early Oral Cancer. Laryngoscope. 2026 Mar; 136(3):1253-1263.
Two decades of the HPV vaccine: its promise, progress, prospects, projections, and posterity. Lancet Reg Health Am. 2025 Nov; 51:101243.
Access to Dental Care for Patients With Cancer-Time for Broader Policy? JAMA Oncol. 2025 Sep 01; 11(9):959-960.
Fluorescence-Guided Surgery for Assessing Margins in Head and Neck Cancer: A Review. JAMA Surg. 2025 Sep 01; 160(9):1018-1023.
Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers. Clin Cancer Res. 2025 Aug 14; 31(16):3483-3493.
Geographic Trends and Geospatial Analysis of Head and Neck Fellowship-Trained Surgeons. Head Neck. 2026 Jan; 48(1):125-133.
The Impact of Postoperative Antibiotics on Outcomes Following Segmental Resection and Microvascular Reconstruction for Mandibular Osteoradionecrosis. Head Neck. 2025 Dec; 47(12):3237-3244.
Donor Site Morbidity of the Medial Sural Artery Perforator (MSAP) Free Flap for Head & Neck Reconstruction. Head Neck. 2025 Oct; 47(10):2710-2715.
Should Private Equity Firms Own Residency Slots? AMA J Ethics. 2025 May 01; 27(5):E325-332.
Thyroid Cancer Incidence and Trends in United States and Canadian Pediatric, Adolescent, and Young Adults. Cancers (Basel). 2025 Apr 24; 17(9).
Immunotherapeutic strategies in head and neck cancer: challenges and opportunities. J Clin Invest. 2025 Apr 15; 135(8).
Back to the Workforce-An Important Marker of Survivorship. JAMA Otolaryngol Head Neck Surg. 2025 Apr 01; 151(4):311-312.
Momordicine-I suppresses head and neck cancer growth by modulating key metabolic pathways. Cell Commun Signal. 2024 Dec 18; 22(1):597.
Shortcomings of excisional biopsy in Early-Stage oral cavity carcinoma. Oral Oncol. 2024 Oct; 157:106909.
Representativeness of U.S. News & World Report Outcome and Volume Measures for Otolaryngology. Laryngoscope. 2024 09; 134(9):3881-3882.
The Clinic Visit. JAMA. 2024 06 25; 331(24):2079-2080.
Intraoperative Ultrasound for the Management of Oral Tongue Cancer: a Systematic Review and Meta-Analysis. OTO Open. 2024 Apr-Jun; 8(2):e147.
Early Weight-Bearing After Fibula Free Flap Surgery. JAMA Otolaryngol Head Neck Surg. 2024 02 01; 150(2):127-132.
Margin distance in oral tongue cancer surgery: A systematic review of survival and recurrence outcomes. Oral Oncol. 2023 12; 147:106609.
Predictors of multiple dilations and functional outcomes after total laryngectomy and laryngopharyngectomy. Head Neck. 2024 01; 46(1):138-144.
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients. Nat Biomed Eng. 2023 12; 7(12):1649-1666.
Functional considerations between flap and non-flap reconstruction in oral tongue cancer: A systematic review. Oral Oncol. 2023 12; 147:106596.
Depth of resection predicts loss of tongue tip sensation after partial glossectomy in oral tongue cancer: A pilot study. Oral Oncol. 2023 12; 147:106595.
Trends in Response Rate to US News & World Report Best Hospitals Reputation Survey, 2015 to 2023. Otolaryngol Head Neck Surg. 2024 Jan; 170(1):284-288.
Margins in Stage I and II Oral Cavity Squamous Cell Carcinoma: A Review From the American Head and Neck Society. JAMA Otolaryngol Head Neck Surg. 2023 07 01; 149(7):636-642.
Adjuvant radiotherapy mitigates impact of perineural invasion on oncologic outcomes in early-stage oral cavity squamous cell carcinoma. A multi-institutional analysis of 557 patients. Oral Oncol. 2023 07; 142:106420.
Development and Content Validity of a Novel Patient-Reported Outcome Measure for Total Laryngectomy: The LARY-Q. J Voice. 2025 Sep; 39(5):1418.e1-1418.e10.
Comparison of patient-reported upper extremity disability following free flaps in head and neck reconstruction: A systematic review and meta-analysis. Head Neck. 2023 07; 45(7):1832-1840.
Lower Facial Nerve Nomenclature Clarification: Cervical Branch Controls Smile-Associated Lower Lip Depression and Dental Display. Otolaryngol Head Neck Surg. 2023 10; 169(4):837-842.
Surgical factors affecting regionally metastatic cutaneous squamous cell carcinoma to the parotid gland. Head Neck. 2023 05; 45(5):1080-1087.
Comparison of Preoperative DOI Estimation in Oral Tongue Cancer With cN0 Disease. Otolaryngol Head Neck Surg. 2023 10; 169(4):948-953.
Correlation of Intraoperative Ultrasonographic Oral Tongue Shape and Border and Risk of Close Margins. Otolaryngol Head Neck Surg. 2023 06; 168(6):1576-1579.
Telemedicine Services Provided to Medicare Beneficiaries by Otolaryngologists in 2020. Otolaryngol Head Neck Surg. 2023 01; 168(1):105-107.
Cross-legged modification for medial sural artery perforator flap harvest. Head Neck. 2023 03; 45(3):752-756.
Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma. Cell Rep. 2022 11 29; 41(9):111743.
Physician Turnover Among Otolaryngologists in the United States, 2014-2021. Laryngoscope. 2023 02; 133(2):235-236.
Rate of atypical nodal metastases in surgically treated HPV-associated oropharyngeal squamous cell carcinoma. Head Neck. 2023 02; 45(2):409-416.
Molecular Biomarkers of Malignant Transformation in Head and Neck Dysplasia. Cancers (Basel). 2022 Nov 15; 14(22).
Medical students' knowledge of HPV, HPV vaccine, and HPV-associated head and neck cancer. Hum Vaccin Immunother. 2022 Nov 30; 18(6):2109892.
Predicting Progression of Oral Lesions to Malignancy Using Machine Learning. Laryngoscope. 2023 05; 133(5):1156-1162.
YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4. Cell Rep. 2022 06 14; 39(11):110970.
First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes. Clin Cancer Res. 2022 06 01; 28(11):2373-2384.
How Far We Have Come. JAMA Otolaryngol Head Neck Surg. 2022 05 01; 148(5):395-396.
Strategies to Increase Racial and Ethnic Diversity in the Surgical Workforce: A State of the Art Review. Otolaryngol Head Neck Surg. 2022 06; 166(6):1182-1191.
Correction to: SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. Mol Cancer. 2022 Mar 31; 21(1):90.
Detection of circulating tumor human papillomavirus DNA before diagnosis of HPV-positive head and neck cancer. Int J Cancer. 2022 10 01; 151(7):1081-1085.
Disparities in Index of Care for Otolaryngologic Procedures Performed in Ambulatory and Inpatient Settings. Otolaryngol Head Neck Surg. 2022 Nov; 167(5):821-831.
A Contemporary Review of Molecular Therapeutic Targets for Adenoid Cystic Carcinoma. Cancers (Basel). 2022 Feb 16; 14(4).
Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer. Clin Cancer Res. 2022 02 15; 28(4):719-727.
Cell-free human papillomavirus DNA kinetics after surgery for human papillomavirus-associated oropharyngeal cancer. Cancer. 2022 06 01; 128(11):2193-2204.
Differential Outcomes Among Survivors of Head and Neck Cancer Belonging to Racial and Ethnic Minority Groups. JAMA Otolaryngol Head Neck Surg. 2022 02 01; 148(2):119-127.
Misestimating Misattribution of Mortality to Otolaryngology Departments in US News & World Report Rankings. Otolaryngol Head Neck Surg. 2022 02; 166(2):403.
Salvage surgery for recurrent squamous cell carcinoma of the head and neck: Systematic review and meta-analysis. Head Neck. 2022 01; 44(1):275-285.
The Future of Fluorescent-Guided Surgery. JAMA Otolaryngol Head Neck Surg. 2021 10 01; 147(10):920.
Rate of COVID-19 Infection in Patients Following Otolaryngology vs Non-otolaryngology Outpatient Encounters. Otolaryngol Head Neck Surg. 2022 08; 167(2):266-267.
The utility of intra-oral ultrasound in improving deep margin clearance of oral tongue cancer resections. Oral Oncol. 2021 11; 122:105512.
Dual Function Antibody Conjugates for Multimodal Imaging and Photoimmunotherapy of Cancer Cells. Photochem Photobiol. 2022 01; 98(1):220-231.
Response to: Should ultrasound-guided resection be the new norm for oral tongue resections? Oral Oncol. 2022 01; 124:105473.
Anastomosis to the Internal Jugular Vein Stump: A Highly Reliable Technique in Head and Neck Reconstruction. Facial Plast Surg Aesthet Med. 2022 Jul-Aug; 24(4):322-323.
Assessment of Preoperative Functional Status Prior to Major Head and Neck Surgery: A Pilot Study. Otolaryngol Head Neck Surg. 2022 04; 166(4):688-695.
Feeding Tube Placement Following Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2022 04; 166(4):696-703.
Comparison between computed tomography and ultrasound for presurgical evaluation of oral tongue squamous cell carcinoma tumor thickness. Am J Otolaryngol. 2021 Nov-Dec; 42(6):103089.
Prediction of Speech, Swallowing, and Quality of Life in Oral Cavity Cancer Patients: A Pilot Study. Laryngoscope. 2021 11; 131(11):2497-2504.
Nasal and paranasal sinus mucosal melanoma: Long-term survival outcomes and prognostic factors. Am J Otolaryngol. 2021 Nov-Dec; 42(6):103070.
Impact of surgical margins on local control in patients undergoing single-modality transoral robotic surgery for HPV-related oropharyngeal squamous cell carcinoma. Head Neck. 2021 08; 43(8):2434-2444.
Opioid prescribing practices in academic otolaryngology: A single institutional survey. Am J Otolaryngol. 2021 Sep-Oct; 42(5):103038.
Graduate Medical Education in Otolaryngology: Making Dollars and Sense of Reform. Otolaryngol Head Neck Surg. 2021 12; 165(6):762-764.
The tipping point in oral cavity reconstruction: A multi-institutional survey of choice between flap and non-flap reconstruction. Oral Oncol. 2021 09; 120:105267.
Prospective assessment of multiple HPV-positive oropharyngeal squamous cell carcinomas. Oral Oncol. 2021 06; 117:105212.
Novel voice prosthesis after total laryngectomy with laryngoplasty reconstruction. Head Neck. 2021 04; 43(4):1321-1330.
Trends in the Implementation of Multidisciplinary Care in Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2020 12 01; 146(12):1146-1148.
Opioid Usage and Prescribing Predictors Following Transoral Robotic Surgery for Oropharyngeal Cancer. Laryngoscope. 2021 06; 131(6):E1888-E1894.
AHNS endocrine surgery section consensus statement on nasopharyngolaryngoscopy and clinic reopening during COVID-19: How to get back to optimal safe care. Head Neck. 2021 02; 43(2):733-738.
Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19. Oral Oncol. 2021 01; 112:105087.
Incomplete Picture of Otolaryngologist Performance in the Merit-Based Incentive Payment System-Reply. JAMA Otolaryngol Head Neck Surg. 2020 11 01; 146(11):1087-1088.
In-Practice Endocrine Surgery Fellowship: A Novel Training Model. Otolaryngol Head Neck Surg. 2021 06; 164(6):1166-1171.
Long non-coding RNA ELDR enhances oral cancer growth by promoting ILF3-cyclin E1 signaling. EMBO Rep. 2020 12 03; 21(12):e51042.
Role of physician density in predicting stage and survival for head and neck squamous cell carcinoma. Head Neck. 2021 02; 43(2):438-448.
In Response to Letter to the Editor Regarding: A Call for Universal Acceptance of the Milan System for Reporting Salivary Gland Cytopathology. Laryngoscope. 2021 04; 131(4):E1105.
Margin Practices in Oral Cavity Cancer Resections: Survey of American Head and Neck Society Members. Laryngoscope. 2021 04; 131(4):782-787.
Risk Factors for Laryngectomy for Dysfunctional Larynx After Organ Preservation Protocols: A Case-Control Analysis. Otolaryngol Head Neck Surg. 2021 03; 164(3):608-615.
National Database Research in Head and Neck Reconstructive Surgery: A Call for Increased Transparency and Reproducibility. Otolaryngol Head Neck Surg. 2021 02; 164(2):315-321.
State Medicaid expansion status, insurance coverage and stage at diagnosis in head and neck cancer patients. Oral Oncol. 2020 11; 110:104870.
Otolaryngologist Performance in the Merit-Based Incentive Payment System in 2017. JAMA Otolaryngol Head Neck Surg. 2020 07 01; 146(7):639-646.
Change in stage of presentation of head and neck cancer in the United States before and after the affordable care act. Cancer Epidemiol. 2020 08; 67:101763.
Reply to letter to the editor (HED-20-0582) regarding "how to avoid nosocomial spread during tracheostomy for COVID-19 patients". Head Neck. 2020 09; 42(9):2770-2771.
Comparison of Intraoperative Sonography and Histopathologic Evaluation of Tumor Thickness and Depth of Invasion in Oral Tongue Cancer: A Pilot Study. AJNR Am J Neuroradiol. 2020 07; 41(7):1245-1250.
Sociodemographic correlates of head and neck cancer survival among patients with metastatic disease. Head Neck. 2020 09; 42(9):2505-2515.
Revaluation of Otolaryngologic Procedures With 10- and 90-Day Global Periods in the Medicare Physician Fee Schedule. Otolaryngol Head Neck Surg. 2020 Oct; 163(4):755-758.
Predicting length of stay in head and neck patients who undergo free flap reconstruction. Laryngoscope Investig Otolaryngol. 2020 Jun; 5(3):461-467.
Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations. Otolaryngol Head Neck Surg. 2020 09; 163(3):465-470.
How to avoid nosocomial spread during tracheostomy for COVID-19 patients. Head Neck. 2020 06; 42(6):1280-1281.
State-Sponsored Price Transparency Initiatives for Otolaryngologic Procedures in 2019. JAMA Otolaryngol Head Neck Surg. 2020 04 01; 146(4):378-380.
Impact of the Patient Protection and Affordable Care Act on cost-related medication underuse in nonelderly adult cancer survivors. Cancer. 2020 06 15; 126(12):2892-2899.
Variation in the Geographic Distribution of the Otolaryngology Workforce: A National Geospatial Analysis. Otolaryngol Head Neck Surg. 2020 05; 162(5):649-657.
Intraoperative Margin Assessment in Head and Neck Cancer: A Case of Misuse and Abuse? Head Neck Pathol. 2020 Jun; 14(2):291-302.
Financial Implications of Site-Neutral Payments for Clinic Visits in Otolaryngology. JAMA Otolaryngol Head Neck Surg. 2020 01 01; 146(1):78-79.
Socioeconomic and Demographic Variation in Insurance Coverage Among Patients With Head and Neck Cancer After the Affordable Care Act. JAMA Otolaryngol Head Neck Surg. 2019 12 01; 145(12):1144-1149.
Rising incidence of late-stage head and neck cancer in the United States. Cancer. 2020 03 01; 126(5):1090-1101.
Outcomes and prognostic factors in parotid gland malignancies: A 10-year single center experience. Laryngoscope Investig Otolaryngol. 2019 Dec; 4(6):632-639.
Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis. Oral Oncol. 2019 12; 99:104458.
Understanding approaches to measurement and impact of depth of invasion of oral cavity cancers: A survey of American Head and Neck Society Membership. Oral Oncol. 2019 12; 99:104461.
Composite Nasoseptal Flap for Palate Reconstruction. J Craniofac Surg. 2019 Oct; 30(7):1990-1993.
Analysis of Potential Conflicts of Interest among Otolaryngologic Patient Advocacy Organizations in 2016. Otolaryngol Head Neck Surg. 2019 12; 161(6):967-969.
Valuation of Commonly Performed Head and Neck Surgical Procedures in the Medicare Physician Fee Schedule. JAMA Otolaryngol Head Neck Surg. 2019 Sep 01; 145(9):866-868.
Letter to the Editor "Stage II Oral Tongue Cancer: Survival Impact of Adjuvant Radiation Based on Depth of Invasion". Otolaryngol Head Neck Surg. 2019 09; 161(3):543.
Prevalence and factors associated with diagnosed depression among hospitalized cancer patients with metastatic disease. Soc Psychiatry Psychiatr Epidemiol. 2020 Jan; 55(1):15-23.
All-Cause 30-Day Mortality After Surgical Treatment for Head and Neck Squamous Cell Carcinoma in the United States. Am J Clin Oncol. 2019 07; 42(7):596-601.
Plunging ranula with lingual nerve tether: Case report and literature review. Am J Otolaryngol. 2019 Jul - Aug; 40(4):612-614.
Preoperative anemia displays a dose-dependent effect on complications in head and neck oncologic surgery. Head Neck. 2019 09; 41(9):3033-3040.
Mucoepidermoid Carcinoma of the Parotid: Very Close Margins and Adjuvant Radiotherapy. ORL J Otorhinolaryngol Relat Spec. 2019; 81(1):55-62.
The Centers for Medicare & Medicaid Services' Overhaul of Office-Visit Payments-What's the Bottom Line for Otolaryngology? JAMA Otolaryngol Head Neck Surg. 2019 Apr 01; 145(4):303-304.
Does Clearance of Positive Margins Improve Local Control in Oral Cavity Cancer? A Meta-analysis. Otolaryngol Head Neck Surg. 2019 08; 161(2):235-244.
Insurance status, stage of presentation, and survival among female patients with head and neck cancer. Laryngoscope. 2020 02; 130(2):385-391.
A Call for Universal Acceptance of the Milan System for Reporting Salivary Gland Cytopathology. Laryngoscope. 2020 01; 130(1):80-85.
What's Love Got to do with it? Marital status and survival of head and neck cancer. Eur J Cancer Care (Engl). 2019 Jul; 28(4):e13022.
United States-based global otolaryngology surgery: A call to more horizontal sustainable efforts. Am J Otolaryngol. 2019 May - Jun; 40(3):404-408.
In response to letter to the editor regarding: "Patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation". Laryngoscope. 2019 05; 129(5):E168.
Assessing functional outcomes in head and neck surgical oncology. Head Neck. 2019 07; 41(7):2051-2057.
Understanding of risk factors for the human papillomavirus (HPV) infection based on gender and race. Sci Rep. 2019 01 22; 9(1):297.
Racial and socioeconomic disparities associated with 90-day mortality among patients with head and neck cancer in the United States. Oral Oncol. 2019 02; 89:95-101.
Patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation. Laryngoscope. 2019 09; 129(9):2059-2064.
Multiple simultaneous head and neck cancers in Lynch syndrome: Case report and literature review. Laryngoscope. 2018 12; 128(12):2759-2761.
Suicide risk among cancer survivors: Head and neck versus other cancers. Cancer. 2018 10 15; 124(20):4072-4079.
Patients with revised surgical resection margins are best studied as a distinct group. Cancer. 2018 11 01; 124(21):4262-4263.
Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study. Psychooncology. 2018 12; 27(12):2809-2814.
Radiation and Second Primary Thyroid Cancer Following Index Head and Neck Cancer. Laryngoscope. 2019 04; 129(4):1014-1020.
Utility of intraoral ultrasound in managing oral tongue squamous cell carcinoma: Systematic review. Laryngoscope. 2019 03; 129(3):662-670.
Bundled Payments in Otolaryngology: Early Lessons from Arkansas. Otolaryngol Head Neck Surg. 2018 12; 159(6):945-947.
Correlates of human papillomavirus (HPV) vaccination initiation and completion among 18-26 year olds in the United States. Hum Vaccin Immunother. 2018; 14(8):2016-2024.
Assessing university students' sexual risk behaviors as predictors of human papillomavirus (HPV) vaccine uptake behavior. Vaccine. 2018 06 14; 36(25):3629-3634.
The Merit-based Incentive Payment System (MIPS): A Primer for Otolaryngologists. Otolaryngol Head Neck Surg. 2018 09; 159(3):410-413.
Factors associated with increased risk of suicide among survivors of head and neck cancer: A population-based analysis. Oral Oncol. 2018 06; 81:29-34.
SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. Mol Cancer. 2018 04 06; 17(1):78.
Opioid Prescription Patterns Among Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2018 Apr 01; 144(4):382-383.
Oncologic and functional outcomes of pretreatment tracheotomy in advanced laryngeal squamous cell carcinoma: A multi-institutional analysis. Oral Oncol. 2018 03; 78:171-176.
Salvage of recurrence after surgery and adjuvant therapy: A systematic review. Am J Otolaryngol. 2018 Mar - Apr; 39(2):223-227.
Primary Cancer vs Competing Causes of Death in Survivors of Head and Neck Cancer. JAMA Oncol. 2018 Feb 01; 4(2):257-259.
Preoperative laboratory data are associated with complications and surgical site infection in composite head and neck surgical resections. Am J Otolaryngol. 2018 May - Jun; 39(3):261-265.
Association Between Head and Neck Squamous Cell Carcinoma Survival, Smoking at Diagnosis, and Marital Status. JAMA Otolaryngol Head Neck Surg. 2018 Jan 01; 144(1):43-50.
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Cell. 2017 Dec 14; 171(7):1611-1624.e24.
Intraoperative Ultrasound in Oral Tongue Cancer Resection: Feasibility Study and Early Outcomes. Otolaryngol Head Neck Surg. 2018 04; 158(4):645-648.
Survival of human papillomavirus-associated cancers: Filling in the gaps. Cancer. 2018 01 01; 124(1):18-20.
Bitter Melon Prevents the Development of 4-NQO-Induced Oral Squamous Cell Carcinoma in an Immunocompetent Mouse Model by Modulating Immune Signaling. Cancer Prev Res (Phila). 2018 04; 11(4):191-202.
40-year incidence trends for oropharyngeal squamous cell carcinoma in the United States. Oral Oncol. 2017 11; 74:90-97.
Decreased cancer-independent life expectancy in the head and neck cancer population. Head Neck. 2017 09; 39(9):1845-1853.
Characteristics and predictors of oral cancer knowledge in a predominantly African American community. PLoS One. 2017; 12(5):e0177787.
Frailty index: Intensive care unit complications in head and neck oncologic regional and free flap reconstruction. Head Neck. 2017 08; 39(8):1578-1585.
Tracheal T-tubes for Long-term Management of the Unreconstructable Trachea in Adults. Otolaryngol Head Neck Surg. 2017 07; 157(1):164-166.
Sociodemographic Factors Associated With Knowledge and Risk Perception of Human Papillomavirus and Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma Among a Predominantly Black Population. JAMA Otolaryngol Head Neck Surg. 2017 02 01; 143(2):117-124.
Impact of treatment modality on quality of life of head and neck cancer patients: Findings from an academic medical institution. Am J Otolaryngol. 2017 Mar - Apr; 38(2):168-173.
Competing causes of death in the head and neck cancer population. Oral Oncol. 2017 02; 65:8-15.
Does a specimen-based margin analysis of early tongue cancer better predict local control? Laryngoscope. 2016 11; 126(11):2426-2427.
Insufficient Evidence to Support or Refute the Association between Head and Neck Cancer and Marijuana Use. J Evid Based Dent Pract. 2016 Jun; 16(2):127-9.
Functional outcomes of sensate versus insensate free flap reconstruction in oral and oropharyngeal reconstruction: A systematic review. Head Neck. 2016 11; 38(11):1717-1721.
Esthesioneuroblastoma with bilateral metastases to the parotid glands. Head Neck. 2016 Jul; 38(7):E2457-E2460.
Impact of Sensory and Motor Defects on Oral Function in an Animal Model. Otolaryngol Head Neck Surg. 2016 08; 155(2):246-51.
Long-Term Outcomes After Proton Beam Therapy for Sinonasal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2016 May 01; 95(1):368-376.
Quality of Physician Communication about HPV Vaccine-Letter. Cancer Epidemiol Biomarkers Prev. 2016 05; 25(5):865.
Oncologic Outcomes of Invasive Squamous Cell Carcinoma of the Scalp Requiring Resection of Cranial Bone. J Neurol Surg A Cent Eur Neurosurg. 2016 Jul; 77(4):308-11.
Suicide: A Major Threat to Head and Neck Cancer Survivorship. J Clin Oncol. 2016 Apr 01; 34(10):1151.
Predictors of stage at presentation and outcomes of head and neck cancers in a university hospital setting. Head Neck. 2016 04; 38 Suppl 1:E1826-32.
Letter to the editor regarding: Management of invasive well-differentiated thyroid cancer: An American Head and Neck Society Consensus Statement. Head Neck. 2016 Feb; 38(2):328-9.
Minimally Invasive Approach to the Lingual and Hypoglossal Nerves in the Adult Rat. J Invest Surg. 2016 Jun; 29(3):144-8.
Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States. J Cancer Res Clin Oncol. 2016 Feb; 142(2):521-8.
Scalp Rotation Flap for Reconstruction of Complex Soft Tissue Defects. J Neurol Surg B Skull Base. 2016 Feb; 77(1):32-7.
CD4+ and CD8+ T cells have opposing roles in breast cancer progression and outcome. Oncotarget. 2015 Jul 10; 6(19):17462-78.
Short-term Peripheral Auditory Effects of Cranial Irradiation: A Mouse Model. Ann Otol Rhinol Laryngol. 2015 Nov; 124(11):903-10.
Surgical margins and primary site resection in achieving local control in oral cancer resections. Laryngoscope. 2015 Oct; 125(10):2298-307.
Improved overall survival and mortality in head and neck cancer with adjuvant concurrent chemoradiotherapy in national databases. Head Neck. 2016 Feb; 38(2):208-15.
Sexual behavior, HPV knowledge, and association with head and neck cancer among a high-risk group. Oral Oncol. 2015 May; 51(5):452-6.
Identification of molecular signature of head and neck cancer stem-like cells. Sci Rep. 2015 Jan 15; 5:7819.
Efficacy of bone marrow cytologic evaluations in detecting occult cancellous invasion. Laryngoscope. 2015 May; 125(5):E173-9.
TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence. EMBO Mol Med. 2014 Oct; 6(10):1294-311.
Evaluation of the definitions of "high-risk" cutaneous squamous cell carcinoma using the american joint committee on cancer staging criteria and national comprehensive cancer network guidelines. J Skin Cancer. 2014; 2014:154340.
Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model. Cancer Gene Ther. 2014 Jun; 21(6):228-237.
Bitter melon reduces head and neck squamous cell carcinoma growth by targeting c-Met signaling. PLoS One. 2013; 8(10):e78006.
Specific recruitment of ?d regulatory T cells in human breast cancer. Cancer Res. 2013 Oct 15; 73(20):6137-48.
PET-CT and the detection of the asymptomatic recurrence or second primary lesions in the treated head and neck cancer patient. Laryngoscope. 2013 Sep; 123(9):2161-4.
Functional similarity between E6 proteins of cutaneous human papillomaviruses and the adenovirus E1A tumor-restraining module. J Virol. 2013 Jul; 87(13):7781-6.
Tumor-derived ?d regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence. J Immunol. 2013 Mar 01; 190(5):2403-14.
Tumor-infiltrating ?d T lymphocytes predict clinical outcome in human breast cancer. J Immunol. 2012 Nov 15; 189(10):5029-36.
Human regulatory T cells induce T-lymphocyte senescence. Blood. 2012 Sep 06; 120(10):2021-31.
Risk of sinonasal-cutaneous fistula after treatment for advanced sinonasal cancer. J Surg Oncol. 2012 Mar; 105(3):261-5.
Salvage surgery following radiation failure for laryngeal cancer in elderly patients. Otolaryngol Head Neck Surg. 2011 Nov; 145(5):759-66.
FDG PET/CT incidental diagnosis of a synchronous bladder cancer as a fourth malignancy in a patient with head and neck cancer. Clin Nucl Med. 2011 Jun; 36(6):496-7.
Single-stage repair of subglottic stenosis using the radial forearm free flap as a vascularized carrier. Head Neck. 2010 Nov; 32(11):1579-83.
Postoperative monitoring in free tissue transfer patients: effective use of nursing and resident staff. Otolaryngol Head Neck Surg. 2009 Nov; 141(5):621-5.
Fistula between the carotid artery and larynx in a 67-year-old man. Ear Nose Throat J. 2009 Aug; 88(8):1030-2.
Down-regulation of multiple cell survival proteins in head and neck cancer cells by an apoptogenic mutant of adenovirus type 5. Virology. 2009 Sep 15; 392(1):62-72.
Microvascular reconstruction of major lip defects. Facial Plast Surg Clin North Am. 2009 May; 17(2):203-9.
Surgery for nasal NK/T-cell lymphoma. Leuk Lymphoma. 2008 Nov; 49(11):2206-8.
Pictorial Essay: Nonmalignant FDG Uptake in the Head and Neck Regions. PET Clin. 2007 Oct; 2(4):445-68.
Right common carotid artery crossing the midline neck anterior to the trachea: a cadaver case report. Head Neck. 2008 Sep; 30(9):1253-6.
The occipital flap for reconstruction after lateral temporal bone resection. Arch Otolaryngol Head Neck Surg. 2008 Jun; 134(6):587-91.
Recent advances in otolaryngology-head and neck surgery. Mo Med. 2008 May-Jun; 105(3):196-7.
Management of oral cavity carcinoma. Mo Med. 2008 May-Jun; 105(3):244-9.
Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies. Otolaryngol Head Neck Surg. 2007 Dec; 137(6):893-8.
Prevention of postexenteration complications by obliteration of the orbital cavity. Skull Base. 2007 May; 17(3):197-203.
Proton beam radiation therapy for skull base adenoid cystic carcinoma. Arch Otolaryngol Head Neck Surg. 2006 Nov; 132(11):1242-9.
Traditional approaches to the orbit. Otolaryngol Clin North Am. 2006 Oct; 39(5):895-909, vi.
Successful myoblast transplantation in rat tongue reconstruction. Head Neck. 2006 Jun; 28(6):517-24.
Surgical margin determination in head and neck oncology: current clinical practice. The results of an International American Head and Neck Society Member Survey. Head Neck. 2005 Nov; 27(11):952-8.
Effects of aspirin and low-dose heparin in head and neck reconstruction using microvascular free flaps. Laryngoscope. 2005 Jun; 115(6):973-6.
Success of multiple, sequential, free tissue transfers to the head and neck. Laryngoscope. 2005 Jan; 115(1):101-4.
End-to-side venous anastomosis with the internal jugular vein stump: a preliminary report. Head Neck. 2004 Jun; 26(6):537-40.
Repair of chronic subglottic stenosis with autogenous thyroid cartilage. Ann Otol Rhinol Laryngol. 2004 Mar; 113(3 Pt 1):212-7.
William W. Montgomery, MD, 1923-2003. Ann Otol Rhinol Laryngol. 2004 Jan; 113(1):1-4.
Reconstruction after orbital exenteration. Arch Ophthalmol. 2003 Nov; 121(11):1662; author reply 1662.
Tissue engineered muscle implantation for tongue reconstruction: a preliminary report. Laryngoscope. 2003 Oct; 113(10):1792-7.
Muscle tissue engineering for partial glossectomy defects. Arch Facial Plast Surg. 2003 Sep-Oct; 5(5):403-7.
Microvascular and microneural surgery new horizons in facial plastic and reconstructive surgery. Facial Plast Surg Clin North Am. 2002 May; 10(2):167-74.
Pathology quiz case 1. Metastatic BCC and lymphoma. Arch Otolaryngol Head Neck Surg. 2002 Jan; 128(1):75, 77-8.
Oral cancer in vivo gene expression profiling assisted by laser capture microdissection and microarray analysis. Oncogene. 2001 Sep 27; 20(43):6196-204.
Hair-bearing temporoparietal fascial flap reconstruction of upper lip and scalp defects. Arch Facial Plast Surg. 2001 Jul-Sep; 3(3):170-7.
Pedicled rhinotomy for clival chordomas invaginating the brainstem. Neurosurg Focus. 2001 Mar 15; 10(3):E8.
Use of the radial forearm fasciocutaneous free flap and montgomery salivary bypass tube for pharyngoesophageal reconstruction. Head Neck. 2000 Aug; 22(5):463-8.
Paraclinoid internal carotid artery aneurysm presenting as massive epistaxis. Ann Otol Rhinol Laryngol. 2000 Aug; 109(8 Pt 1):782-6.
Mucocele of the infratemporal fossa as an unusual complication of midfacial fracture. Ann Otol Rhinol Laryngol. 2000 May; 109(5):522-5.
Montgomery Thyroplasty Implant for vocal fold immobility: phonatory outcomes. Ann Otol Rhinol Laryngol. 2000 Apr; 109(4):393-400.
Histological pattern of mandibular invasion by oral squamous cell carcinoma. Laryngoscope. 2000 Jan; 110(1):65-72.
Anomalous relationship of the facial nerve and the retromandibular vein: a case report. J Oral Maxillofac Surg. 1999 Jan; 57(1):75-6.
Combining free flap reconstruction and craniofacial prosthetic technique for orbit, scalp, and temporal defects. Laryngoscope. 1998 Apr; 108(4 Pt 1):482-7.
Evaluation of chemotherapy response in patients with advanced head and neck cancer using [F-18]fluorodeoxyglucose positron emission tomography. Head Neck. 1997 Dec; 19(8):666-74.
Expression of p53 protein in advanced head and neck squamous cell carcinoma before and after chemotherapy. Arch Otolaryngol Head Neck Surg. 1997 Nov; 123(11):1223-5.
Erythropoietin reduces anemia and transfusions after chemotherapy with paclitaxel and carboplatin. Cancer. 1997 Apr 15; 79(8):1623-8.
Changes in quality-of-life scores in a population of patients treated for squamous cell carcinoma of the head and neck. Head Neck. 1996 Nov-Dec; 18(6):487-93.
Assessment of functional morbidity in the radial forearm free flap donor site. Arch Otolaryngol Head Neck Surg. 1996 Sep; 122(9):991-4.
Management of airway obstruction in cicatricial pemphigoid. Laryngoscope. 1996 Aug; 106(8):1014-7.
Massive, destructive, dentigerous cyst: A case report. Otolaryngol Head Neck Surg. 1996 Jul; 115(1):141-4.
Relationship between psychological status and compliance in a sample of patients treated for cancer of the head and neck. Head Neck. 1996 May-Jun; 18(3):269-76.
Hodgkin's disease primarily involving Waldeyer's ring. Case report and review of the literature. Arch Pathol Lab Med. 1996 Mar; 120(3):285-7.
Descending necrotizing mediastinitis: a complication of dental implant surgery. Head Neck. 1996 Mar-Apr; 18(2):192-6.
Teflon granuloma of the larynx: etiology, pathophysiology, and management. Ann Otol Rhinol Laryngol. 1995 Jul; 104(7):511-5.
Voice rehabilitation after laryngectomy. Mo Med. 1995 Mar; 92(3):145-7.
Combined thyroplasty type I and inferior constrictor myotomy. Ann Otol Rhinol Laryngol. 1994 Nov; 103(11):858-62.
Thyroplasty: a new approach. Ann Otol Rhinol Laryngol. 1993 Aug; 102(8 Pt 1):571-9.
The temporoparietal fascial flap in head and neck reconstruction. Arch Otolaryngol Head Neck Surg. 1993 Jun; 119(6):618-23.
Cutaneous squamous cell carcinoma occurring in a pectoralis major myocutaneous flap. Case report and literature review. Ann Otol Rhinol Laryngol. 1993 Mar; 102(3 Pt 1):206-8.
Chondroblastoma of the temporal bone. Case report and literature review. Ann Otol Rhinol Laryngol. 1992 Sep; 101(9):763-9.
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Mike Toth Head and Neck Cancer Research Center
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