Nancy Klimas, M.D. | College of Osteopathic Medicine | Nova Southeastern University

Nancy Klimas, M.D. | College of Osteopathic Medicine | Nova Southeastern University
Faculty and Staff
Osteopathic
People
Nancy Klimas, M.D.
Nancy Klimas, M.D.
Title:
Director - INIM/Chair/Assistant Dean - Research/Professor
Department:
Institute for Neuro-Immune Medicine
College/Division:
Dr. Kiran C. Patel College of Osteopathic Medicine
Email:
nklimas@nova.edu
Phone:
(305) 255-5464
Nancy Klimas, M.D., has 40 years of professional experience and has achieved international
recognition for her research and clinical efforts in multi-symptom disorders, myalgic
encephalomyelitis/chronic fatigue syndrome (ME/CFS), Gulf War illness (GWI), fibromyalgia,
and most recently Long COVID.
She is the director of the Institute for Neuro-Immune Medicine, assistant dean of
Research, and professor of Clinical Immunology at the Dr. Kiran C. Patel College of
Osteopathic Medicine. She chairs the Department of Clinical Immunology at Nova Southeastern
University. Klimas is professor emerita, at the University of Miami’s Miller School
of Medicine where she practiced for 30 years,  a diplomat of the American Board of
Internal Medicine, a diplomat in Diagnostic Laboratory Immunology, and director of
Environmental Medicine Research at the Miami Veterans Affairs Medical Center Geriatric
Research Education and Clinical Center (GRECC).
She has achieved national and international recognition for her research and clinical
efforts in multi-symptom disorders, including ME/CFS and GWI. She is a past president
of the International Association for ME/CFS and a past member of the Health and Human
Services CFS Advisory Committee., the VA GWI Research Advisory Committee, the National
Academy of Medicine’s ME/CFS clinical case definition working group, and has served
on several NIH advisory panels.
She founded the NSU Institute for Neuro-Immune Medicine, where she directs a group
of 18 remarkable interdisciplinary scientists and clinicians who are working together
from bedside to bench and back to bedside, working to discover and implement innovative
strategies that effectively treat or prevent these disabling chronic illnesses, while
training the next generation of clinicians and scientists.
NIH R21: Male-specific genomic mechanisms of transcriptional regulation of ME/CFS/SEID
In an effort to provide insight into the key biological targets involved in sex-specific
ME/CFS/SEID presentation, the main objective of this research proposal is to identify
male-specific biomarkers and therapeutic targets of
ME/CFS/SEID and provide insight into sex-specific disease onset and progression, which
will lead to the better therapeutic intervention
VA
MERIT: Women vs. Men with GWI: Differences in Computational Models and Therapeutic
Target
We hypothesize that GWI affects regulatory function differently in women than in
men, with implications on therapeutic management. The objective of this study is to
improve our understanding of GWI pathogenesis in women by: (i) integrating data across
several of the body’s regulatory systems, and (ii) mapping of dysfunctional signaling
networks in GWI in each sex.
NIH R01: Gender Differences in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The proposed study will correct a gender imbalance in ME/CFS research. It may lead
to phase 1 trials of targeted therapies designed to restore a normal balance of autonomic,
immune and endocrine systems and thus, health in men and women.
DoD CDMRR/GWIC: Brain-Immune Interactions as the Basis of Gulf War Illness: Gulf War
Illness Consortium (GWIC)
My role in the consortium is to provide core immune and genomic lab support to the
investigators, and to evaluate the usefulness of biomarkers of inflammation in GWI.
DoD CDMRP/GWIRC: Understanding Gulf War Illness: An Integrative Modeling Approach
Integrate two animal models of GWI with human clinical data to pinpoint the underlying
mechanisms of disease and target treatment more effectively to re-establish normal
well-coordinated signaling interactions. Specifically, our more detailed understanding
of the dysfunction associated with key metabolic pathways involved in GWI would greatly
expedite the identification of promising biomarkers for improved diagnosis over the
short-term as well as selection and testing of more targeted therapeutic interventions
over the longer term that will address the underlying mechanisms of disease.
VA MERIT: A Translational Medicine Approach to Gulf War Illness: From Cells to Therapy
The objectives of the proposed study are to determine if intervening at these therapeutic
targets selected via computational modeling will act as predicted and normalize immune
and neuroendocrine function in an in vitro system. The study will have 2 phases: an
exploration/ screening phase and a validation phase. The screening phase will be conducted
on 17 repurposed drugs. These will be assessed in vitro using whole blood cultures
from 40 GWI patients and 40 matched controls. The most promising 5 drugs will be validated
in PBMCs from a new cohort of 40 GWI patients and 40 matched controls.
CDC: Clinical Assessment of Patients with CFS and Biorepository Development
Goal of project is to enable CFS researchers to provide a standardized approach to
definition use in clinical diagnosis and management of CFS and improve standardization,
integration, and sharing of CFS data to benefit research. Role is to oversee the clinical
components of this work at our site, including the training and supervision of the
clinical staff, and to assist the interdisciplinary team in the clinical utility of
the findings.
NIH R15: Genomic approach to find novel biomarkers and mechanisms of CFS/ME
The employment of advanced genomic technologies and a well-rounded research approach
will allow us to identify regulators of transcription that result in characteristic
symptomatology associated with CFS/ME in female patients.
DoD GWIRP/ IIREA:Testing the Model: A Phase I/II Randomized Double Blind Placebo Control
Trial of Therapeutics: Liposomal Glutathione and Curcumin
The goal is to implement a phase I/II placebo control double blinded 3 arm study
of liposomal glutathione, curcumin and placebo in GWI in 75 veterans with GWI (25
per arm) and assess the safety, feasibility and clinical response to the interventions;.
Integrate repeat assessment and modeling of dynamic response to exercise challenge
in order to map homeostatic pathways before and after 12 weeks of intervention. Finally,
assess antioxidant and methylation-related metabolic status prior to, during, and
after acute exercise in GWI subjects before and after these antioxidant interventions.
2022
A pilot reverse virtual screening study suggests toxic exposures caused long-term
epigenetic changes in Gulf War Illness
Jean-Pierre M, Michalovicz LT, Kelly KA, O'Callaghan JP, Nathanson L, Klimas N, J
A Craddock T. Comput Struct Biotechnol J. 2022 Nov 8;20:6206-6213. doi: 10.1016/j.csbj.2022.11.006.
PMID: 36420170; PMCID: PMC9676197.
Post COVID-19 joint pain: Preliminary report of the relationship with antinuclear
antibodies and inflammation
Tamariz L, Bast E, Abad M, Klimas N, Caralis P, Palacio A. J Med Virol. 2022 Aug;94(8):3479-3481.
doi: 10.1002/jmv.27753. Epub 2022 Apr 9. PMID: 35355291; PMCID: PMC9088578.
Host gut resistome in Gulf War chronic multisymptom illness correlates with persistent
inflammation
Bose D, Chatterjee S, Older E, Seth R, Janulewicz P, Saha P, Mondal A, Carlson JM,
Decho AW, Sullivan K, Klimas N, Lasley S, Li J, Chatterjee S. Commun Biol. 2022 Jun
7;5(1):552. doi: 10.1038/s42003-022-03494-7. PMID: 35672382; PMCID: PMC9174162.
The impact of post-traumatic stress on quality of life and fatigue in women with Gulf
War Illness
Shastry N, Sultana E, Jeffrey M, Collado F, Kibler J, DeLucia C, Fletcher MA, Klimas
N, Craddock TJA. BMC Psychol. 2022 Feb 25;10(1):42. doi: 10.1186/s40359-022-00752-5.
PMID: 35216624; PMCID: PMC8876751.
Sex-specific differences in plasma lipid profiles are associated with Gulf War Illness
Oberlin S, Nkiliza A, Parks M, Evans JE, Klimas N, Keegan AP, Sullivan K, Krengel
MH, Mullan M, Crawford F, Abdullah L. J Transl Med. 2022 Feb 5;20(1):73. doi: 10.1186/s12967-022-03272-3.
PMID: 35123492; PMCID: PMC8817550.
Dry Eye Symptoms and Signs in US Veterans With Gulf War Illness
Sanchez V, Baksh BS, Cabrera K, Choudhury A, Jensen K, Klimas N, Galor A. Am J Ophthalmol.
2022 May;237:32-40. doi: 10.1016/j.ajo.2021.11.010. Epub 2021 Nov 13. PMID: 34780800;
PMCID: PMC9035031.
2021
Associations of Immune Genetic Variability with Gulf War Illness in 1990-1991 Gulf
War Veterans from the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study
Coller JK, Tuke J, Wain TJ, Quinn E, Steele L, Abreu M, Aenlle K, Klimas N, Sullivan
K. Brain Sci. 2021 Oct 26;11(11):1410. doi: 10.3390/brainsci11111410. PMID: 34827409;
PMCID: PMC8615505.
A randomized phase II remote study to assess Bacopa for Gulf War Illness associated
cognitive dysfunction: Design and methods of a national study
Cheema AK, Wiener LE, McNeil RB, Abreu MM, Craddock T, Fletcher MA, Helmer DA, Ashford
JW, Sullivan K, Klimas NG. Life Sci. 2021 Oct 1;282:119819. doi: 10.1016/j.lfs.2021.119819.
PMID: 34256038.
Sex-specific plasma lipid profiles of ME/CFS patients and their association with pain,
fatigue, and cognitive symptoms
Nkiliza A, Parks M, Cseresznye A, Oberlin S, Evans JE, Darcey T, Aenlle K, Niedospial
D, Mullan M, Crawford F, Klimas N, Abdullah L. J Transl Med. 2021 Aug 28;19(1):370.
doi: 10.1186/s12967-021-03035-6. PMID: 34454515; PMCID: PMC8401202.
Brain-Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and
Deployment Profile of 1990-1991 Gulf War Veterans in the Gulf War Illness Consortium
(GWIC) Multisite Case-Control Study
Steele L, Klimas N, Krengel M, Quinn E, Toomey R, Little D, Abreu M, Aenlle K, Killiany
R, Koo BB, Janulewicz P, Heeren T, Clark AN, Ajama J, Cirillo J, Buentello G, Lerma
V, Coller JK, Sullivan K. Brain Sci. 2021 Aug 26;11(9):1132. doi: 10.3390/brainsci11091132.
PMID: 34573153; PMCID: PMC8467437.
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management
Bateman L, Bested AC, Bonilla HF, Chheda BV, Chu L, Curtin JM, Dempsey TT, Dimmock
ME, Dowell TG, Felsenstein D, Kaufman DL, Klimas NG, Komaroff AL, Lapp CW, Levine
SM, Montoya JG, Natelson BH, Peterson DL, Podell RN, Rey IR, Ruhoy IS, Vera-Nunez
MA, Yellman BP. Mayo Clin Proc. 2021 Aug 23:S0025-6196(21)00513-9. doi: 10.1016/j.mayocp.2021.07.004.
PMID: 34454716.
A common language for Gulf War Illness (GWI) research studies: GWI common data elements
Cohen DE, Sullivan KA, McNeil RB, Klimas NG; Gulf War Illness Common Data Elements
Working Group; Symptoms Assessment Working Group, McNeil R, Ashford W, Bested A, Bunker
J, Cheema A, Cohen D, Cook D, Cournoyer J, Craddock T, Golier J, Hardie A, Helmer
D, Lindheimer JB, Lloyd PJ, Kerr K, Krengel M, Nadkarni S, Nugent S, Paris B, Reinhard
M, Rumm P, Schneiderman A, Sims KJ, Steele L, Turner M; Systems Assessment Working
Group, Sullivan K, Abdullah L, Abreu M, Abu-Donia M, Aenlle K, Arocho J, Balbin E,
Baraniuk J, Block K, Block M, DeBeer B, Engdahl B, Filipov N, Fletcher MA, Kalasinsky
V, Kokkotou E, Lidie K, Little D, Loging W, Morris M, Nathanson L, Nichols MD, Pasinetti
G, Shungu D, Waziry P, VanLeeuwen J, Younger J; GWI CDE Administrative Team, Klimas
N. Life Sci. 2021 Aug 2:119818. doi: 10.1016/j.lfs.2021.119818. PMID: 34352259.
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness
by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory
Crosstalk
Saha P, Skidmore PT, Holland LA, Mondal A, Bose D, Seth RK, Sullivan K, Janulewicz
PA, Horner R, Klimas N, Nagarkatti M, Nagarkatti P, Lim ES, Chatterjee S. Brain Sci.
2021 Jul 9;11(7):905. doi: 10.3390/brainsci11070905. PMID: 34356139; PMCID: PMC8304847.
Neurotoxicant exposures and rates of Chronic Multisymptom Illness and Kansas Gulf
War Illness criteria in Gulf War deployed women veterans
Krengel M, Sullivan K, Heboyan V, Zundel CG, Wilson CC, Klimas N, Coughlin SS. Life
Sci. 2021 Sep 1;280:119623. doi: 10.1016/j.lfs.2021.119623. Epub 2021 May 15. PMID:
34004246.
Modeling Neuroimmune Interactions in Human Subjects and Animal Models to Predict Subtype-Specific
Multidrug Treatments for Gulf War Illness
Carrera Arias FJ, Aenlle K, Abreu M, Holschbach MA, Michalovicz LT, Kelly KA, Klimas
N, O'Callaghan JP, Craddock TJA. Int J Mol Sci. 2021 Aug 9;22(16):8546. doi: 10.3390/ijms22168546.
PMID: 34445252; PMCID: PMC8395153.
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A collaborative
research infrastructure for intervention and implementation
Cheema AK, McNeil RB, Craddock T, Broderick G, Abreu MM, Aenlle K, Helmer DA, Ashford
JW, Sullivan K, Bested A, Cohen DE, Shungu D, Chandler H, Fletcher MA, Krengel M,
Klimas N. Life Sci. 2021 Aug 1;278:119636. doi: 10.1016/j.lfs.2021.119636. Epub 2021
May 17. PMID: 34015289.
Elevated somatic mutation and evidence of genomic instability in veterans with Gulf
War illness
Grant SG, Ibrahim OM, Jin XL, Klimas NG, Sullivan K, Latimer JJ. Life Sci. 2021 Jun
26;281:119746. doi: 10.1016/j.lfs.2021.119746. Epub ahead of print. PMID: 34181965.
The effect of stress on the transcriptomes of circulating immune cells in patients
with Gulf War Illness
Van Booven D, Zarnowski O, Perez M, Sarria L, Collado F, Hansotia K, Riegle S, Finger
T, Fletcher MA, Klimas NG, Nathanson L. Life Sci. 2021 Jun 16;281:119719. doi: 10.1016/j.lfs.2021.119719.
Epub ahead of print. PMID: 34144055.
Post-traumatic stress impact on health outcomes in Gulf War Illness
Jeffrey M, Collado F, Kibler J, DeLucia C, Messer S, Klimas N, Craddock TJA. BMC Psychol.
2021 Apr 20;9(1):57. doi: 10.1186/s40359-021-00561-2. PMID: 33879264; PMCID: PMC8056666.
Evaluation of natural killer cell assay performance on shipped blood specimens
Querec TD, Abrams J, Stewart JJ, Barnes Z, Balbin E, Klimas N, Fletcher MA, Brown
L, Bertolli J, Unger ER. J Immunol Methods. 2021 Apr 2;495:113049. doi: 10.1016/j.jim.2021.113049.
Epub ahead of print. PMID: 33819446.
Ocular manifestations and biomarkers of Gulf War Illness in US veterans
Baksh BS, Zayan KL, Goldhardt R, Felix ER, Klimas N, Galor A. Sci Rep. 2021 Mar 22;11(1):6548.
doi: 10.1038/s41598-021-86061-0. PMID: 33753811; PMCID: PMC7985482.
Sex-Based Differences in Plasma Autoantibodies to Central Nervous System Proteins
in Gulf War Veterans versus Healthy and Symptomatic Controls
Abou-Donia MB, Krengel MH, Lapadula ES, Zundel CG, LeClair J, Massaro J, Quinn E,
Conboy LA, Kokkotou E, Nguyen DD, Abreu M, Klimas NG, Sullivan K. Brain Sci. 2021
Jan 23;11(2):148. doi: 10.3390/brainsci11020148. PMID: 33498629; PMCID: PMC7911379.
2020
Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered
Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation
in a Mouse Model
Bose D, Saha P, Mondal A, Fanelli B, Seth RK, Janulewicz P, Sullivan K, Lasley S,
Horner R, Colwell RR, Shetty AK, Klimas N, Chatterjee S. Nutrients. 2020 Sep 10;12(9):2764.
doi: 10.3390/nu12092764. PMID: 32927823; PMCID: PMC7551189.
Using Plasma Autoantibodies of Central Nervous System Proteins to Distinguish Veterans
with Gulf War Illness from Healthy and Symptomatic Controls
Abou-Donia MB, Lapadula ES, Krengel MH, Quinn E, LeClair J, Massaro J, Conboy LA,
Kokkotou E, Abreu M, Klimas NG, Nguyen DD, Sullivan K. Brain Sci. 2020 Sep 5;10(9):610.
doi: 10.3390/brainsci10090610. PMID: 32899468; PMCID: PMC7563126.
Plasma proteomic profiling suggests an association between antigen driven clonal B
cell expansion and ME/CFS
Milivojevic M, Che X, Bateman L, Cheng A, Garcia BA, Hornig M, Huber M, Klimas NG,
Lee B, Lee H, Levine S, Montoya JG, Peterson DL, Komaroff AL, Lipkin WI. PLoS One.
2020 Jul 21;15(7):e0236148. doi: 10.1371/journal.pone.0236148. PMID: 32692761; PMCID:
PMC7373296.
Unravelling Myalgic encephalomyelitis/chronic Fatigue Syndrome (ME/CFS): Gender-specific
Changes in the microRNA Expression Profiling in ME/CFS
Cheema AK, Sarria L, Bekheit M, et al. J Cell Mol Med. 2020;24(10):5865-5877. doi:10.1111/jcmm.15260
Leveraging Prior Knowledge to Recover Characteristic Immune Regulatory Motifs in Gulf
War Illness
Vashishtha S, Broderick G, Craddock TJA, et al. Front Physiol. 2020;11:358. Published
2020 Apr 28. doi:10.3389/fphys.2020.00358
Targeting Sirtuin Activity With Nicotinamide Riboside Reduces Neuroinflammation in
a GWI Mouse Model
Joshi U, Evans JE, Pearson A, et al. Neurotoxicology. 2020;79:84-94. doi:10.1016/j.neuro.2020.04.006
Prevalence and Patterns of Symptoms Among Female Veterans of the 1991 Gulf War Era:
25 Years Later
Sullivan K, Krengel M, Heboyan V, et al. J Women's Health (Larchmt). 2020;29(6):819-826.
doi:10.1089/jwh.2019.7705
Preliminary Evidence for a Hormetic Effect on DNA Nucleotide Excision Repair in Veterans
With Gulf War Illness
Latimer JJ, Alhamed A, Sveiven S, et al. Mil Med. 2020;185(1-2):e47-e52. doi:10.1093/milmed/usz177
Post-exertional Malaise Is Associated With Greater Symptom Burden and Psychological
Distress in Patients Diagnosed With Chronic Fatigue Syndrome
May M, Milrad SF, Perdomo DM, et al. J Psychosom Res. 2020;129:109893. doi:10.1016/j.jpsychores.2019.109893
Towards a Treatment for Gulf War Illness: A Consensus Docking Approach
Jaundoo R, Bohmann J, Gutierrez GE, Klimas N, Broderick G, Craddock TJA. Mil Med.
2020;185(Suppl 1):554-561. doi:10.1093/milmed/usz299
2019
Gut DNA Virome Diversity and Its Association With Host Bacteria Regulate Inflammatory
Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness
Seth RK, Maqsood R, Mondal A, et al. 2019;11(10):968. Published 2019 Oct 21. doi:10.3390/v11100968
Dysbiosis-Associated Enteric Glial Cell Immune-Activation and Redox Imbalance Modulate
Tight Junction Protein Expression in Gulf War Illness Pathology
Kimono D, Sarkar S, Albadrani M, et al. Front Physiol. 2019;10:1229. Published 2019
Oct 14. doi:10.3389/fphys.2019.01229
The Gut-Microbiome in Gulf War Veterans: A Preliminary Report
Janulewicz PA, Seth RK, Carlson JM, et al. Int J Environ Res Public Health. 2019;16(19):3751.
Published 2019 Oct 4. doi:10.3390/ijerph16193751
Neuropsychological Findings in Gulf War Illness: A Review
Jeffrey MG, Krengel M, Kibler JL, et al. Front Psychol. 2019;10:2088. Published 2019
Sep 26. doi:10.3389/fpsyg.2019.02088
A Permethrin Metabolite Is Associated With Adaptive Immune Responses in Gulf War Illness
Joshi U, Pearson A, Evans JE, et al. Brain Behav Immun. 2019;81:545-559. doi:10.1016/j.bbi.2019.07.015
Relationship Satisfaction, Communication Self-Efficacy, and Chronic Fatigue Syndrome-Related
Fatigue
Milrad SF, Hall DL, Jutagir DR, et al. Soc Sci Med. 2019;237:112392. doi:10.1016/j.socscimed.2019.112392
Sex Differences in Gulf War Illness: A Reanalysis of Data From the CDC Air Force Study
Using CDC and Modified Kansas Case Definitions
Heboyan V, Krengel MH, Sullivan K, et al. J Occup Environ Med. 2019;61(7):610-616.
doi:10.1097/JOM.0000000000001620
Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic
Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study
Perez M, Jaundoo R, Hilton K, Del Alamo A, Gemayel K, Klimas NG, Craddock TJA, Nathanson
L. Front Pediatr. 2019 May 24;7:206. doi: 10.3389/fped.2019.00206.
Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant
Phenotyping of Women With Chronic Fatigue Syndrome
Morris MC, Cooney KE, Sedghamiz H, Abreu M, Collado F, Balbin EG, Craddock TJA, Klimas
NG, Broderick G, Fletcher MA.Clin Ther. 2019 Apr;41(4):656-674.e4. doi: 10.1016/j.clinthera.2019.03.002.
Alterations in DNA Methylation Status Associated with Gulf War Illness
Trivedi MS, Abreu MM, Sarria L, Rose N, Ahmed N, Beljanski V, Fletcher MA, Klimas
NG, Nathanson L. DNA Cell Biol. 2019 Jun;38(6):561-571. doi: 10.1089/dna.2018.4469.
Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary
Richman S, Morris MC, Broderick G, Craddock TJA, Klimas NG, Fletcher MA. Clin Ther.
2019 May;41(5):798-805. doi: 10.1016/j.clinthera.2019.02.011.
Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender
Pharmacogenomic Study of Gene-expression Modules
Jeffrey MG, Nathanson L, Aenlle K, Barnes ZM, Baig M, Broderick G, Klimas NG, Fletcher
MA, Craddock TJA. Clin Ther. 2019 May;41(5):815-835.e6. doi: 10.1016/j.clinthera.2019.01.011.
Corticosterone and Pyridostigmine/DEET Exposure Attenuate Peripheral Cytokine Expression:
Supporting a Dominant Role for Neuroinflammation in a Mouse Model of Gulf War Illness
Michalovicz LT, Locker AR, Kelly KA, Miller JV, Barnes Z, Fletcher MA, Miller DB,
Klimas NG, Morris M, Lasley SM, O'Callaghan JP. Neurotoxicology. 2019 Jan;70:26-32.
doi: 10.1016/j.neuro.2018.10.006.
2018
A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation
in the Perpetuation of Neuroinflammation
Craddock TJA, Michalovicz LT, Kelly KA, et al. Front Cell Neurosci. 2018;12:336. Published
2018 Oct 15. doi:10.3389/fncel.2018.00336
The Gulf War Era Cohort and Biorepository: A Longitudinal Research Resource of Veterans
of the 1990-1991 Gulf War Era
Khalil L, McNeil RB, Sims KJ, et al. Am J Epidemiol. 2018;187(11):2279-2291. doi:10.1093/aje/kwy147
Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA
Methylation Patterns
Trivedi MS, Oltra E, Sarria L, et al. PLoS One. 2018;13(7):e0201066. Published 2018
Jul 23. doi:10.1371/journal.pone.0201066
Insights into Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Phenotypes through
Comprehensive Metabolomics
Nagy-Szakal D, Barupal DK, Lee B, et al. Sci Rep. 2018;8(1):10056. Published 2018
Jul 3. doi:10.1038/s41598-018-28477-9
Psychoneuroimmunology and Natural Killer Cells: The Chromium-Release Whole-Blood Assay
Fletcher MA, Barnes Z, Broderick G, Klimas NG. Methods Mol Biol. 2018;1781:209-220.
doi:10.1007/978-1-4939-7828-1_12
Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression
Tory Toole J, Rice MA Jr, Craddock TJA, et al. Methods Mol Biol. 2018;1781:121-144.
doi:10.1007/978-1-4939-7828-1_8
Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness
Broderick G, Fletcher MA, Gallagher M, Barnes Z, Vernon SD, Klimas NG. Methods Mol
Biol. 2018;1781:101-120. doi:10.1007/978-1-4939-7828-1_7
Increasing Resilience to Traumatic Stress: Understanding the Protective Role of Well-Being
Tory Toole J, Rice MA Jr, Cargill J, et al. Methods Mol Biol. 2018;1781:87-100. doi:10.1007/978-1-4939-7828-1_6
2017
Fecal Metagenomic Profiles in Subgroups of Patients with Myalgic Encephalomyelitis/Chronic
Fatigue Syndrome
Nagy-Szakal D, Williams BL, Mishra N, Che X, Lee B, Bateman L, Klimas NG, Komaroff
AL, Levine S, Montoya JG, Peterson DL, Ramanan D, Jain K, Eddy ML, Hornig M, Lipkin
WI. Microbiome. 2017 Apr 26;5(1):44. doi: 10.1186/s40168-017-0261-y.
Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
(MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study
Unger ER, Lin JS, Tian H, Natelson BH, Lange G, Vu D, Blate M, Klimas NG, Balbin EG,
Bateman L, Allen A, Lapp CW, Springs W, Kogelnik AM, Phan CC, Danver J, Podell RN,
Fitzpatrick T, Peterson DL, Gottschalk CG, Rajeevan MS; MCAM Study Group. Am J Epidemiol.
2017 Apr 15;185(8):617-626. doi: 10.1093/aje/kwx029.
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Gulf War Illness Patients Exhibit
Increased Humoral Responses to the Herpesviruses-encoded dUTPase: Implications in
Disease Pathophysiology
Halpin P, Williams MV, Klimas NG, Fletcher MA, Barnes Z, Ariza ME. J Med Virol. 2017
Sep;89(9):1636-1645. doi: 10.1002/jmv.24810. Epub 2017 Apr 26.
2016
Gastric Enterovirus Infection: A Possible Causative Etiology of Gastroparesis
Barkin JA, Czul F, Barkin JS, Klimas NG, Rey IR, Moshiree B. Dig Dis Sci. 2016 Aug;61(8):2344-50.
doi: 10.1007/s10620-016-4227-x.
Tracking Post-Infectious Fatigue in Clinic Using Routine Lab Tests
Russell L, Broderick G, Taylor R, Fernandes H, Harvey J, Barnes Z, Smylie A, Collado
F, Balbin EG, Katz BZ, Klimas NG, Fletcher MA. BMC Immunol. 2016 Mar 10;17:3. doi:
10.1186/s12865-016-0142-3.
Illness Progression in Chronic Fatigue Syndrome: A Shifting Immune Baseline
Russell L, Broderick G, Taylor R, Fernandes H, Harvey J, Barnes Z, Smylie A, Collado
F, Balbin EG, Katz BZ, Klimas NG, Fletcher MA. BMC Immunol. 2016 Mar 10;17:3. doi:
10.1186/s12865-016-0142-3.
Recent Research on Gulf War Illness and Other Health Problems in Veterans of the 1991
Gulf War: Effects of Toxicant Exposures During Deployment
Bloom, F.E., Bunker, J.A., Crawford, F., Graves, J.C., Hardie, A., Klimas, N., Knox,
M., Meggs, W.J., Melling, J., Philbert, M.A., & Grashow, R. Cortex. 2016 Jan;74:449-75.
doi: 10.1016/j.cortex.2015.08.022.
2015
Findings from a clinical and laboratory database developed for discovery of pathogenic
mechanisms in myalgic encephalomyelitis/chronic fatigue syndrome
N.G. Klimas, G. Ironson, A. Carter, E. Balbin, L. Bateman, D. Felsenstein, S. Levine,
D. Peterson, K. Chiu, A. Allen, K. Cunningham, C.G. Gottschalk, M. Fletcher, M. Hornig,
C. Canning & A.L. Komaroff. Fatigue: Biomedicine, Health & Behavior, Volume 3, 2015
- Issue 2
Achieving Remission in Gulf War Illness: A Simulation-Based Approach to Treatment
Design
Craddock TJ, Del Rosario RR, Rice M, Zysman JP, Fletcher MA, Klimas NG, Broderick
G. PLoS One. 2015 Jul 20;10(7):e0132774. doi: 10.1371/journal.pone.0132774. eCollection
2015.
Perceived Fatigue Interference and Depressed Mood: Comparison of Chronic Fatigue Syndrome/Myalgic
Encephalomyelitis Patients with Fatigued Breast Cancer Survivors
Hall DL, Antoni MH, Lattie EG, Jutagir DR, Czaja SJ, Perdomo D, Lechner SC, Stagl
JM, Bouchard LC, Gudenkauf LM, Traeger L, Fletcher M, Klimas NG. Fatigue. 2015;3(3):142-155.
Using Gene Expression Signatures to Identify Novel Treatment Strategies in Gulf War
Illness
Craddock TJ, Harvey JM, Nathanson L, Barnes ZM, Klimas NG, Fletcher MA, Broderick
G. BMC Med Genomics. 2015 Jul 9;8:36. doi: 10.1186/s12920-015-0111-3.
Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper
Bound Under Constraints Typical of In Vivo Studies?
Vashishtha S, Broderick G, Craddock TJ, Fletcher MA, Klimas NG. PLoS One. 2015 May
18;10(5):e0127364. doi: 10.1371/journal.pone.0127364. eCollection 2015.
Distinct Plasma Immune Signatures in ME/CFS are Present Early in the Course Of Illness
Hornig M, Montoya JG, Klimas NG, Levine S, Felsenstein D, Bateman L, Peterson DL,
Gottschalk CG, Schultz AF, Che X, Eddy ML, Komaroff AL, Lipkin WI. Sci Adv. 2015 Feb;1(1).
pii: e1400121.
2014
No Association Found Between the Detection of Either Xenotropic Murine Leukemia Virus-Related
Virus or Polytropic Murine Leukemia Virus and Chronic Fatigue Syndrome in a Blinded,
Multi-Site, Prospective Study by the Establishment and Use of the SolveCFS BioBank.
Irlbeck DM, Vernon SD, McCleary KK, Bateman L, Klimas NG, Lapp CW, Peterson DL, Brown
JR, Remlinger KS, Wilfret DA, Gerondelis P. BMC Res Notes. 2014 Aug 4;7:461. doi:
10.1186/1756-0500-7-461.
Stress Management Skills, Cortisol Awakening Response, and Post-Exertional Malaise
in Chronic Fatigue Syndrome
Hall DL, Lattie EG, Antoni MH, Fletcher MA, Czaja S, Perdomo D, Klimas NG. Psychoneuroendocrinology.
2014 Nov;49:26-31. doi: 10.1016/j.psyneuen.2014.06.021. Epub 2014 Jul 6.
A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: Gulf
War Illness and Chronic Fatigue Syndrome
Craddock TJ, Fritsch P, Rice MA Jr, del Rosario RM, Miller DB, Fletcher MA, Klimas
NG, Broderick G. PLoS One. 2014 Jan 8;9(1):e84839. doi: 10.1371/journal.pone.0084839.
eCollection 2014. Erratum in: PLoS One. 2014;9(4):e94161. PLoS One. 2014;9(6):e100355.
2013
Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Symptom Severity:
Stress Management Skills are Related to Lower Illness Burden
Lattie, E.G., Antoni, M.H., Fletcher, M.A., Czaja, S., Perdomo, D., Sala, A., Nair,
S., Fu, S.H., Penedo, F.J., Klimas, N. Fatigue. 2013;1(4). doi: 10.1080/21641846.2013.843255.
A Comparison of Sex-Specific Immune Signatures in Gulf War Illness and Chronic Fatigue
Syndrome
Smylie, A.L., Broderick, G., Fernandes, H., Razdan, S., Barnes, Z., Collado, F., Sol,
C., Fletcher, M.A., Klimas, N. BMC Immunol. 2013 Jun 25;14:29. doi: 10.1186/1471-2172-14-29.
Altered Immune Pathway Activity Under Exercise Challenge in Gulf War Illness: An Exploratory
Analysis
Broderick, G., Ben-Hamo, R., Vashishtha, S., Efroni, S., Nathanson, L., Barnes, Z.,
Fletcher, M.A., Klimas, N. Brain Behav Immun. 2013 Feb;28:159-69. doi: 10.1016/j.bbi.2012.11.007.
2012
A Multicenter Blinded Analysis Indicates No Association Between Chronic Fatigue Syndrome/Myalgic
Encephalomyelitis and Either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic
Murine Leukemia Virus
Alter, H.J., Mikovits, J.A., Switzer, W.M., Ruscetti, F.W., Lo, S.C., Klimas, N.,
Komaroff, A.L., Montoya, J.G., Bateman, L., Levine, S., Peterson, D., Levin, B., Hanson,
M.R., Genfi, A., Bhat, M., Zheng, H., Wang, R., Li, B., Hung, G.C., Lee, L.L., Sameroff,
S., Heneine, W., Coffin, J., Hornig, M., Lipkin, W.I. MBio. 2012 Sep 18;3(5). pii:
e00266-12. doi: 10.1128/mBio.00266-12.
Cytokine Expression Profiles of Immune Imbalance in Post-Mononucleosis Chronic Fatigue
Broderick, G., Katz, B.Z., Fernandes, H., Fletcher, M.A., Klimas, N., Smith, F.A.,
O'Gorman, M.R., Vernon, S.D., Taylor, R. J Transl Med. 2012 Sep 13;10:191. doi: 10.1186/1479-5876-10-191.
Psychoneuroimmunology and Natural Killer Cells: The Chromium Release Whole Blood Assay
Fletcher MA, Barnes Z, Broderick G, Klimas NG. Methods Mol Biol. 2012;934:313-24.
doi: 10.1007/978-1-62703-071-7_16.
Exploring the Diagnostic Potential of Immune Biomarker Coexpression in Gulf War Illness
Broderick G, Fletcher MA, Gallagher M, Barnes Z, Vernon SD, Klimas NG. Methods Mol
Biol. 2012;934:145-64. doi: 10.1007/978-1-62703-071-7_8.
Biomarkers for Chronic Fatigue
Klimas NG, Broderick G, Fletcher MA. Brain Behav Immun. 2012 Nov;26(8):1202-10. doi:
10.1016/j.bbi.2012.06.006.
Stress Management Skills, Neuroimmune Processes and Fatigue Levels in Persons with
Chronic Fatigue Syndrome
Lattie, E.G., Antoni, M.H., Fletcher, M.A., Penedo, F., Czaja, S., Lopez, C., Perdomo,
D., Sala, A., Nair, S., Fu, S.H., Klimas, N. Brain Behav Immun. 2012 Aug;26(6):849-58.
doi: 10.1016/j.bbi.2012.02.008.
Minimum Data Elements for Research Reports on CFS
Jason, L.A., Unger, E.R., Dimitrakoff, J.D., Fagin, A.P., Houghton, M., Cook, D.B.,
Marshall, G.D. Jr., Klimas, N., Snell, C. Brain Behav Immun. 2012 Mar;26(3):401-6.
doi: 10.1016/j.bbi.2012.01.014.
2011
Myalgic Encephalomyelitis: International Consensus Criteria
Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T,
Staines D, Powles AC, Speight N, Vallings R, Bateman L, Baumgarten-Austrheim B, Bell
DS, Carlo-Stella N, Chia J, Darragh A, Jo D, Lewis D, Light AR, Marshall-Gradisnik
S, Mena I, Mikovits JA, Miwa K, Murovska M, Pall ML, Stevens S. J Intern Med. 2011
Oct;270(4):327-38. doi: 10.1111/j.1365-2796.2011.02428.x.
Immunological Abnormalities as Potential Biomarkers in Chronic Fatigue Syndrome/Myalgic
Encephalomyelitis
Brenu EW, van Driel ML, Staines DR, Ashton KJ, Ramos SB, Keane J, Klimas NG, Marshall-Gradisnik
SM. J Transl Med. 2011 May 28;9:81. doi: 10.1186/1479-5876-9-81.
A Pilot Study of Cognitive Behavioral Stress Management Effects on Stress, Quality
of Life, and Symptoms in Persons with Chronic Fatigue Syndrome
Lopez, C., Antoni, M., Penedo, F., Weiss, D., Cruess, S., Segotas, M.C., Helder, L.,
Siegel, S., Klimas, N., Fletcher, M.A. J Psychosom Res. 2011 Apr;70(4):328-34. doi:
10.1016/j.jpsychores.2010.11.010.
Stress Buffering Effects of Oxytocin on HIV Status in Low-Income Ethnic Minority Women
Fekete, E.M., Antoni, M.H., Lopez, C., Mendez, A.J., Szeto, A., Fletcher, M.A., Klimas,
N., Kumar, M., Schneiderman, N. Psychoneuroendocrinology. 2011 Jul;36(6):881-90. doi:
10.1016/j.psyneuen.2010.12.003.
A Pilot Study of Immune Network Remodeling Under Challenge in Gulf War Illness
Broderick, G., Kreitz, A., Fuite, J., Fletcher, M.A., Vernon, S.D., Klimas, N. Brain
Behav Immun. 2011 Feb;25(2):302-13. doi: 10.1016/j.bbi.2010.10.011.
2010
Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive
men
S. McPherson-Baker , R.M. Malow , F. Penedo , D.L. Jones , N. Schneiderman & N.G.
Klimas. Pages 399-404 | Published online: 27 May 2010
Plasma Neuropeptide Y: A Biomarker for Symptom Severity in Chronic Fatigue Syndrome
Fletcher, M.A., Rosenthal, M., Antoni, M., Ironson, G., Zeng, X.R., Barnes, Z., Harvey,
J.M., Hurwitz, B., Levis, S., Broderick, G., Klimas, N.G. Behav Brain Funct. 2010
Dec 29;6:76. doi: 10.1186/1744-9081-6-76.
Long-Term Safety of Testosterone and Growth Hormone Supplementation: A Retrospective
Study of Metabolic, Cardiovascular, and Oncologic Outcomes
Ginzburg, E., Klimas, N., Parvus, C., Life, J., Willix, R., Barber, M.J., Lin, A.,
Comite, F. J Clin Med Res. 2010 Aug 18;2(4):159-66. doi: 10.4021/jocmr428w.
Biomarkers in Chronic Fatigue Syndrome: Evaluation of Natural Killer Cell Function
and Dipeptidyl Peptidase IV/CD26
Fletcher, M.A., Zeng, X.R., Maher, K., Levis, S., Hurwitz, B., Antoni, M., Broderick,
G., Klimas, N.G. PLoS One. 2010 May 25;5(5):e10817. doi: 10.1371/journal.pone.0010817.
A Formal Analysis of Cytokine Networks in Chronic Fatigue Syndrome
Broderick, G., Fuite, J., Kreitz, A., Vernon, S.D., Klimas, N., Fletcher, M.A. Brain
Behav Immun. 2010 Oct;24(7):1209-17. doi: 10.1016/j.bbi.2010.04.012.
2009
Plasma Cytokines in Women with Chronic Fatigue Syndrome
Fletcher, M.A., Zeng, X.R., Barnes, Z., Levis, S., Klimas, N.G. J Transl Med. 2009
Nov 12;7:96. doi: 10.1186/1479-5876-7-96.
Men's Serostatus Disclosure to Parents: Associations Among Social Support, Ethnicity,
and Disease Status in Men Living with HIV
Fekete, E.M., Antoni, M.H., Lopez, C.R., Durán, R.E., Penedo, F.J., Bandiera, F.C.,
Fletcher, M.A., Klimas, N., Kumar, M., Schneiderman, N. Brain Behav Immun. 2009 Jul;23(5):693-9.
doi: 10.1016/j.bbi.2009.01.007.
Chronic Fatigue Syndrome: Illness Severity, Sedentary Lifestyle, Blood Volume and
Evidence of Diminished Cardiac Function
Hurwitz, B.E., Coryell, V.T., Parker, M., Martin, P., Laperriere, A., Klimas, N.G.,
Sfakianakis, G.N., Bilsker, M.S. Clin Sci (Lond). 2009 Oct 19;118(2):125-35. doi:
10.1042/CS20090055.
Impaired Immune Function in Gulf War Illness
Whistler, T., Fletcher, M.A., Lonergan, W., Zeng, X.R., Lin, J.M., Laperriere, A.,
Vernon, S.D., Klimas, N.G. BMC Med Genomics. 2009 Mar 5;2:12. doi: 10.1186/1755-8794-2-12.
2008
Overview of HIV
Klimas, N., Koneru, A.O., Fletcher, M.A. Psychosom Med. 2008 Jun;70(5):523-30. doi:
10.1097/PSY.0b013e31817ae69f.
Psychological Distress, Killer Lymphocytes And Disease Severity in HIV/AIDS
Greeson, J.M., Hurwitz, B.E., Llabre, M.M., Schneiderman, N., Penedo, F.J., Klimas,
N.G. Brain Behav Immun. 2008 Aug;22(6):901-11. doi: 10.1016/j.bbi.2008.01.001.
Testosterone and Growth Hormone Normalization: A Retrospective Study of Health Outcomes
Ginzburg, E., Lin, A., Sigler, M., Olsen, D., Klimas, N., Mintz, A. J Multidiscip
Healthc. 2008 Sep 1;1:79-86.
2007
Chronic Fatigue Syndrome: Inflammation, Immune Function, and Neuroendocrine Interactions
Klimas, N.G., Koneru, A.O. Curr Rheumatol Rep. 2007 Dec;9(6):482-7.
Fatigue: Case Definition and Guidelines for Collection, Analysis, and Presentation
of Immunization Safety Data
Jones, J.F., Kohl, K.S., Ahmadipour, N., Bleijenberg, G., Buchwald, D., Evengard,
B., Jason, L.A., Klimas, N.G., Lloyd, A., McCleary, K., Oleske, J.M., White, P.D.
Vaccine. 2007 Aug 1;25(31):5685-96. Epub 2007 Mar 12.
Predictors of CD4 Count Change Over 8 Months of Follow Up in HIV-1-Infected Patients
with a CD4 Count>or=300 cells/microL Who Were Assigned to 7.5 MIU Interleukin-2
ESPRIT Research Group, Fox, Z., Antunes, F., Davey, R., Gazzard, B., Klimas, N., Labriola,
A., Losso, M., Neaton, J.D., Phillips, A.N., Ruxrungtham, K., Staszewski, S., Weiss,
L., Lundgren, J.D. HIV Med. 2007 Mar;8(2):112-23.
2006
Spouses of Persian Gulf War I Veterans: Medical Evaluation of a U.S. Cohort
Eisen, S.A., Karlinsky, J., Jackson, L.W., Blanchard, M., Kang, H.K., Murphy, F.M.,
Alpern, R., Reda, D.J., Toomey, R., Battistone, M.J., Parks, B.J., Klimas, N., Pak,
H.S., Hunter, J., Lyons, M.J., Henderson, W.G. Mil Med. 2006 Jul;171(7):613-8.
Social Support Mediates Loneliness and Human Herpesvirus Type 6 (HHV-6) Antibody Titers
Dixon, D., Cruess, S., Kilbourn, K., Klimas, N., Fletcher, M.A., Ironson, G., Baum,
A., Schneiderman, N., Antoni, M.H. Health Psychol. 2004 Jul;23(4):413-418. doi: 10.1037/0278-6133.23.4.413.
Impaired Natural Immunity, Cognitive Dysfunction, and Physical Symptoms in Patients
with Chronic Fatigue Syndrome: Preliminary Evidence for a Subgroup?
Siegel, S.D., Antoni, M.H., Fletcher, M.A., Maher, K., Segota, M.C., Klimas, N. J
Psychosom Res. 2006 Jun;60(6):559-66.
Exploration of Statistical Dependence Between Illness Parameters Using the Entropy
Correlation Coefficient
Craddock, R.C., Taylor, R., Broderick, G., Whistler, T., Klimas, N., Unger, E.R. Pharmacogenomics.
2006 Apr;7(3):421-8.
Identifying Illness Parameters in Fatiguing Syndromes Using Classical Projection Methods
Broderick, G., Craddock, R.C., Whistler, T., Taylor, R., Klimas, N., Unger, E.R. Pharmacogenomics.
2006 Apr;7(3):407-19.
Gene Expression Correlates of Unexplained Fatigue
Whistler, T., Taylor, R., Craddock, R.C., Broderick, G., Klimas, N., Unger, E.R. Pharmacogenomics.
2006 Apr;7(3):395-405.
Reductions in Depressed Mood and Denial Coping During Cognitive Behavioral Stress
Management with HIV-Positive Gay Men Treated with HAART
Carrico, A.W., Antoni, M.H., Duran, R.E., Ironson, G., Penedo, F., Fletcher, M.A.,
Klimas, N., Schneiderman, N. Ann Behav Med. 2006 Apr;31(2):155-64.
Randomized Clinical Trial of Cognitive Behavioral Stress Management on Human Immunodeficiency
Virus Viral Load in Gay Men Treated with Highly Active Antiretroviral Therapy
Antoni, M.H., Carrico, A.W., Durán, R.E., Spitzer, S., Penedo, F., Ironson, G., Fletcher,
M.A., Klimas, N., Schneiderman, N. Psychosom Med. 2006 Jan-Feb;68(1):143-51.
2005
Psychosocial Factors Predict CD4 And Viral Load Change in Men and Women with Human
Immunodeficiency Virus in the Era of Highly Active Antiretroviral Treatment
Ironson, G., O'Cleirigh, C., Fletcher, M.A., Laurenceau, J.P., Balbin, E., Klimas,
N., Schneiderman, N., Solomon, G. Psychosom Med. 2005 Nov-Dec;67(6):1013-21.
Cognitive Behavioral Stress Management Effects on Mood, Social Support, and a Marker
of Antiviral Immunity are Maintained Up to 1 Year in HIV-infected Gay Men
Carrico, A.W., Antoni, M.H., Pereira, D.B., Fletcher, M.A., Klimas, N., Lechner, S.C.,
Schneiderman, N. Int J Behav Med. 2005;12(4):218-26.
Sympathoimmune Anomalies Underlying the Response to Stressful Challenge in Human Immunodeficiency
Virus Spectrum Disease
Hurwitz, B.E., Brownley, K.A., Motivala, S.J., Milanovich, J.R., Kibler, J.L., Fillion,
L., LeBlanc, W.G., Kumar, M., Klimas, N.G., Fletcher, M.A., Schneiderman, N. Psychosom
Med. 2005 Sep-Oct;67(5):798-806.
Gulf War Veterans' Health: Medical Evaluation of a U.S. Cohort
Eisen, S.A., Kang, H.K., Murphy, F.M., Blanchard, M.S., Reda, D.J., Henderson, W.G.,
Toomey, R., Jackson, L.W., Alpern, R., Parks, B.J., Klimas, N., Hall, C., Pak, H.S.,
Hunter, J., Karlinsky, J., Battistone, M.J., Lyons, M.J. Ann Intern Med. 2005 Jun
7;142(11):881-90.
Increases in a Marker of Immune System Reconstitution are Predated by Decreases in
24-h Urinary Cortisol Output and Depressed Mood During a 10-Week Stress Management
Intervention in Symptomatic HIV-infected Men
Antoni, M.H., Cruess, D.G., Klimas, N., Carrico, A.W., Maher, K., Cruess, S., Lechner,
S.C., Kumar, M., Lutgendorf, S., Ironson, G., Fletcher, M.A., Schneiderman, N. J Psychosom
Res. 2005 Jan;58(1):3-13.
Stress-Associated Changes in the Steady-State Expression of Latent Epstein-Barr Virus:
Implications for Chronic Fatigue Syndrome and Cancer
Glaser, R., Padgett, D.A., Litsky, M.L., Baiocchi, R.A., Yang, E.V., Chen, M., Yeh,
P.E., Klimas, N.G., Marshall, G.D., Whiteside, T., Herberman, R., Kiecolt-Glaser,
J., Williams, M.V. Brain Behav Immun. 2005 Mar;19(2):91-103.
Development and Implementation of a Medication Adherence Training Instrument for Persons
Living with HIV: The MATI
McPherson-Baker, S., Jones, D., Durán, R.E., Klimas, N., Schneiderman, N. Behav Modif.
2005 Mar;29(2):286-317.