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Detection of Extracellular Vesicles with Colocalized Surface Markers via a Capture-Release-Capture Strategy for Treatment Monitoring in Ewing Sarcoma. Adv Healthc Mater. 2026 Feb 22; e05917. Ji YR, Ju Y, Kong H, Xu Y, Zhao C, Zhang R, Ma Y, Zheng LL, Shi LR, Wu A, Lin LA, Wu CP, Qian A, Ren E, Zhang C, Vo K, Dry S, Crompton JG, Federman N, Zhu Y, Jonas SJ, Tseng HR, Lu S, Lee J. PMID: 41725127.
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Exposure to Acetaminophen (Paracetamol) during Pregnancy and Childhood Cancer: A Population-Based Cohort Study in Taiwan. Cancer Epidemiol Biomarkers Prev. 2026 Feb 03; 35(2):330-340. Sirirungreung A, Lee PC, Hu YH, Liew Z, Federman N, Ritz B, Heck JE. PMID: 41342591; PMCID: PMC12782464.
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Five-Day Preoperative Radiation Therapy for Patients With High-Risk Soft Tissue Sarcoma: A Nonrandomized Clinical Trial. JAMA Netw Open. 2025 Dec 01; 8(12):e2550195. Nikitas J, Kendal JK, Savjani RR, Jackson N, Peterson N, Deng J, Hernandez J, Chong N, Singh AS, Chmielowski B, Federman NC, Crompton JG, Kadera BE, Wessel LE, Christ AB, Nelson SD, Dry SM, Weidhaas JB, Steinberg ML, Bernthal NM, Eilber FC, Kalbasi A, Reddy VK. PMID: 41405883; PMCID: PMC12712729.
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Dedicated review of sarcoma pathology is necessary for corroborative diagnosis in nearly one half of referred patients. Surgery. 2025 Dec; 188:109610. Eckardt MA, Siena NM, Copeland AR, McCaw TR, Shehata MS, Lofftus SY, Graham DS, Dao HB, Singh AS, Chmielowski B, Federman N, Kadera BE, Kalbasi A, Bernthal NM, Eilber FR, Dry SM, Nelson SD, Eilber FC, Crompton JG. PMID: 41072121.
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Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance. Signal Transduct Target Ther. 2025 Sep 30; 10(1):319. Storey CM, Altai M, Lückerath K, Zedan W, Zhu H, Breuer L, Trajkovic-Arsic M, Park J, Hasson A, Siveke J, Abou D, Marks H, Ulmert E, Ridley A, Safi M, Lamminmäki U, Yuen C, Geres S, Mao L, Cheng M, Subudhi SK, Siddiqui BA, Federman N, Czernin J, Herrmann K, Bentolila L, Yang X, Graeber TG, Damoiseaux R, Thorek D, Ulmert D. PMID: 41022704; PMCID: PMC12480655.
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Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children's Oncology Group. Eur J Cancer. 2025 Aug 26; 226:115600. Crane JN, Douglass DP, Oberoi S, Collins NB, Gupta A, Metts JL, Avutu V, Dela Cruz FS, Davis JL, Federman NC, Hiniker SM, Laetsch TW, Linardic CM, Navid F, Saab R, Shulman DS, Shern JF, Soragni A, Stewart EA, Terezakis S, Weigel BJ, Weiss AR. PMID: 40651390; PMCID: PMC12409922.
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Human cancer-targeted immunity via transgenic hematopoietic stem cell progeny. Nat Commun. 2025 Jul 01; 16(1):5599. Nowicki TS, Deen NNA, Peters CW, Comin-Anduix B, Medina E, Puig-Saus C, Carretero IB, Kaplan-Lefko P, Macabali MH, Garcilazo IP, Chen D, Pang J, Berent-Maoz B, Haile S, Rodriguez J, Kawakami M, Kidd CK, Champhekar A, Carlucci G, Vega-Crespo A, Chmielowski B, Singh A, Federman N, Schiller GM, Larson SJ, Allen-Auerbach M, Klomhaus AM, Zack J, Baltimore D, Yang L, Kohn DB, Witte ON, Ribas A. PMID: 40593578; PMCID: PMC12219382.
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Neoadjuvant Chemotherapy Is Associated With Reduced Amputation Risk in Synovial Sarcoma of the Lower Extremity. J Surg Oncol. 2025 Jul; 132(1):217-225. Wahle CF, Newman-Hung NJ, Sakowitz S, Federman N, Singh AS, Bernthal NM, Benharash P, Wessel LE. PMID: 40391918.
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Erratum: 160 Empowering future healthcare leaders and clinical researchers across a decade: UCLA's Clinical and Translational Science Institute - Research Associates Program - CORRIGENDUM. J Clin Transl Sci. 2025; 9(1):e84. Selim O, Chen T, Shaker-Irwin L, Federman N, Morrison J, Gellene D, Saha A, Garcia B. PMID: 40384753; PMCID: PMC12083198.
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Achieving durable response with the TRK inhibitor larotrectinib, and possible discontinuation of therapy in pediatric NTRK gene fusion-positive solid tumors. Clin Adv Hematol Oncol. 2025 Apr; 23 Suppl 5(2):1-12. Federman N, Hamilton C. PMID: 40153616.
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Erratum: Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors. J Clin Oncol. 2025 Apr; 43(10):1270. Mascarenhas L, DuBois SG, Albert CM, Bielack S, Orbach D, Federman N, Geoerger B, Nagasubramanian R, Zhang Y, Chisholm J, Melcon SG, Goto H, Morgenstern DA, Owens C, Pappo AS, Perreault S, Schulte JH, Shukla N, Zwaan CM, Neu N, Bernard-Gauthier V, De La Cuesta E, van Tilburg CM, Laetsch TW. PMID: 40030088; PMCID: PMC11949202.
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Erratum: Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors. J Clin Oncol. 2025 Mar 10; 43(8):1046. Mascarenhas L, DuBois SG, Albert CM, Bielack S, Orbach D, Federman N, Geoerger B, Nagasubramanian R, Zhang Y, Chisholm J, Melcon SG, Goto H, Morgenstern DA, Owens C, Pappo AS, Perreault S, Schulte JH, Shukla N, Zwaan CM, Neu N, Bernard-Gauthier V, De La Cuesta E, van Tilburg CM, Laetsch TW. PMID: 39951654; PMCID: PMC11895811.
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Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors. J Clin Oncol. 2025 Apr; 43(10):1180-1187. Mascarenhas L, DuBois SG, Albert CM, Bielack S, Orbach D, Federman N, Geoerger B, Nagasubramanian R, Zhang Y, Chisholm J, Gallego Melcon S, Goto H, Morgenstern DA, Owens C, Pappo AS, Perreault S, Schulte JH, Shukla N, Zwaan CM, Neu N, Bernard-Gauthier V, De La Cuesta E, van Tilburg CM, Laetsch TW. PMID: 39869835; PMCID: PMC11949228.
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Evaluating the implementation and impact of a volunteer navigation oncology support programme: study protocol for a pragmatic, real-world hybrid type 2 study. BMJ Open. 2025 Jan 20; 15(1):e088047. Rocque GB, Dent DN, Waugh C, Hill EK, Federman N, Bostock Rosenzweig I, Morris B, Kamal A. PMID: 39832972; PMCID: PMC11748934.
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The landscape of drug sensitivity and resistance in sarcoma. Cell Stem Cell. 2024 Oct 03; 31(10):1524-1542.e4. Al Shihabi A, Tebon PJ, Nguyen HTL, Chantharasamee J, Sartini S, Davarifar A, Jensen AY, Diaz-Infante M, Cox H, Gonzalez AE, Norris S, Sperry J, Nakashima J, Tavanaie N, Winata H, Fitz-Gibbon ST, Yamaguchi TN, Jeong JH, Dry S, Singh AS, Chmielowski B, Crompton JG, Kalbasi AK, Eilber FC, Hornicek F, Bernthal NM, Nelson SD, Boutros PC, Federman NC, Yanagawa J, Soragni A. PMID: 39305899; PMCID: PMC12318355.
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Selpercatinib prior to radioactive iodine for pediatric papillary thyroid carcinoma. J Pediatr Endocrinol Metab. 2024 Nov 26; 37(11):1009-1014. Chiu HK, Nowicki TS, Livhits MJ, Wu JX, Federman N. PMID: 39239989.
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Erratum: 120 Impact of Undergraduate Clinical Research Experience: Highlighting the UCLA Clinical and Translational Science Institute Research Associates Program (CTSI-RAP) - CORRIGENDUM. J Clin Transl Sci. 2024; 8(1):e108. Piring A, Morrison J, Federman N, Shaker-Irwin L, Duong-Brett S. PMID: 39655017; PMCID: PMC11626596.
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Entinostat as a combinatorial therapeutic for rhabdomyosarcoma. Sci Rep. 2024 08 15; 14(1):18936. Chauhan S, Lian E, Habib I, Liu Q, Anders NM, Bugg MM, Federman NC, Reid JM, Stewart CF, Cates T, Michalek JE, Keller C. PMID: 39147820; PMCID: PMC11327338.
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Open-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma. J Clin Oncol. 2024 Nov; 42(31):3725-3734. Meyers PA, Federman N, Daw N, Anderson PM, Davis LE, Kim A, Macy ME, Pietrofeso A, Ratan R, Riedel RF, Trucco M, Breitmeyer JB, Toretsky JA, Ludwig JA. PMID: 38954782; PMCID: PMC11521759.
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Clinical characteristics and treatment patterns of patients with NTRK fusion-positive solid tumors: A multisite cohort study at US academic cancer centers. J Manag Care Spec Pharm. 2024 Jul; 30(7):672-683. Willis C, Au T, Hejazi A, Griswold C, Schabath MB, Thompson J, Malhotra J, Federman N, Ko G, Appukkuttan S, Warnock N, Kong SX, Hocum B, Brixner D, Stenehjem D. PMID: 38950155; PMCID: PMC11217863.
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Proceedings of the Think Tank for Osteosarcoma Medical Advisory Board. Anticancer Res. 2024 Jul; 44(7):2765-2768. Chawla SP, VAN Tine B, Federman N, Schwab J, Jones R, Subbiah V, Chawla NS, Afshar N, Hoos W, Feldman N, Spencer HT, Swaney W, Gordon EM. PMID: 38925853.
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Maternal Exposure to Heavy Metals From Industrial Sources During Pregnancy and Childhood Cancer Risk in California. J Occup Environ Med. 2024 Sep 01; 66(9):714-721. Chen Y, Van Deventer D, Nianogo R, Vinceti M, Kang W, Cockburn M, Federman N, Heck JE. PMID: 38845100; PMCID: PMC11371530.
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Onset and resolution of ovarian toxicity with nirogacestat treatment in females with desmoid tumors: Updated safety analyses from the DeFi phase 3 study. Cancer. 2024 Aug 15; 130(16):2812-2821. Loggers ET, Chugh R, Federman N, Hartner L, Riedel RF, Cho S, Hyslop D, Lim A, Oton AB, Oktay KH. PMID: 38703010.
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Maternal residential exposure to solvents from industrial sources during pregnancy and childhood cancer risk in California. Int J Hyg Environ Health. 2024 Jun; 259:114388. Chen Y, Van Deventer D, Nianogo R, Vinceti M, Kang W, Cockburn M, Federman N, Heck JE. PMID: 38704950; PMCID: PMC11127780.
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Erratum: 120 Impact of Undergraduate Clinical Research Experience: Highlighting the UCLA Clinical and Translational Science Institute Research Associates Program (CTSI-RAP) - CORRIGENDUM. J Clin Transl Sci. 2024; 8(1):e68. Piring A, Morrison J, Federman N, Shaker-Irwin L, Duong-Brett S. PMID: 38690222; PMCID: PMC11058573.
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Effects of hypertension and use of antihypertensive drugs in pregnancy on the risks of childhood cancers in Taiwan. Cancer Causes Control. 2024 Jul; 35(7):1053-1061. Orimoloye HT, Hu YH, Federman N, Ritz B, Arah OA, Li CY, Lee PC, Heck JE. PMID: 38557933; PMCID: PMC11520249.
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Editorial: Celebrating the 200th mendel's anniversary: gene-targeted diagnostics and therapies for cancer. Front Mol Med. 2024; 4:1366963. Federman N, Gordon EM, Chawla SP, Hall FL. PMID: 39086436; PMCID: PMC11285536.
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Orbital indeterminate cell histiocytosis. Orbit. 2025 Feb; 44(1):96-100. Oh AJ, Sears CM, Vadivelan AA, Gomperts BN, Federman N, Said J, Roelofs KA. PMID: 38374584.
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Sarcoma in patients with Lynch syndrome and response to immunotherapy. J Surg Oncol. 2024 Mar; 129(4):820-826. Shehata MS, Lofftus SY, Park JY, Singh AS, Federman NC, Eilber FC, Crompton JG, McCaw TR. PMID: 38151827.
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From Mendel to Gene Therapy. Anticancer Res. 2023 10; 43(10):4257-4261. Jeffrey SL, Brigham DA, Chawla SP, Federman N, Hall FL, Gordon EM. PMID: 37772566.
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Exploring Barriers to Pediatric Cancer Clinical Trials: The Role of a Networked, Just-in-Time Study Program. Clin Ther. 2023 11; 45(11):1148-1150. Rivers Z, Hyde B, Ronski K, Stearns D, Toll S, Ritt K, Cooney M, Nimeiri H, Federman N, Kaneva K. PMID: 37783645.
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A review of the therapeutic potential of histone deacetylase inhibitors in rhabdomyosarcoma. Front Oncol. 2023; 13:1244035. Selim O, Song C, Kumar A, Phelan R, Singh A, Federman N. PMID: 37664028; PMCID: PMC10471891.
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The landscape of drug sensitivity and resistance in sarcoma. bioRxiv. 2023 Aug 08. Al Shihabi A, Tebon PJ, Nguyen HTL, Chantharasamee J, Sartini S, Davarifar A, Jensen AY, Diaz-Infante M, Cox H, Gonzalez AE, Swearingen S, Tavanaie N, Dry S, Singh A, Chmielowski B, Crompton JG, Kalbasi A, Eilber FC, Hornicek F, Bernthal N, Nelson SD, Boutros PC, Federman N, Yanagawa J, Soragni A. PMID: 37292676; PMCID: PMC10245988.
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Adolescent and Young Adult (AYA) Oncology, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 08; 21(8):851-880. Bhatia S, Pappo AS, Acquazzino M, Allen-Rhoades WA, Barnett M, Borinstein SC, Casey R, Choo S, Chugh R, Dinner S, Ermoian R, Fair D, Federman N, Folbrecht J, Gandhi S, Germann J, Goldsby R, Hayashi R, Huang AY, Huang MS, Jacobs LA, Lee-Miller C, Link MP, Livingston JA, Lustberg M, Malogolowkin M, Oeffinger KC, Pratilas CA, Reed D, Skiles J, von Mehren M, Yeager N, Montgomery S, Hang L. PMID: 37549914.
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Fibroblast Activation Protein Expression in Sarcomas. Sarcoma. 2023; 2023:2480493. Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC. PMID: 37333052; PMCID: PMC10275689.
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A pilot study evaluating the use of sirolimus in children and young adults with desmoid-type fibromatosis. Pediatr Blood Cancer. 2023 Jun 07; e30466. Weiss AR, Dry S, Maygar C, Cutler A, Lary CW, Khoo C, Fergione JE, Hounchell MM, Glick K, Browning M, Choo SH, Hawkins DS, Lagmay J, Manalang M, Skapek SX, Weigel B, Verwys S, Federman N. PMID: 37283290.
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Successful treatment of severe immune checkpoint inhibitor associated autoimmune hepatitis with basiliximab: a case report. Front Immunol. 2023; 14:1156746. Zarrabi M, Hamilton C, French SW, Federman N, Nowicki TS. PMID: 37325672; PMCID: PMC10262312.
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Maternal migraine and risk of pediatric cancers. Pediatr Blood Cancer. 2023 07; 70(7):e30385. Orimoloye HT, Heck JE, Charles A, Saechao C, He D, Federman N, Olsen J, Ritz B, Hansen J. PMID: 37101365; PMCID: PMC10278537.
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Pediatric Rectal Adenocarcinoma With Mismatch Repair Deficiency Responds to Immunotherapy. JCO Precis Oncol. 2023 04; 7:e2200378. Qureshi N, Hoffman TL, Kaneva K, Zomorrodian S, Scapa JV, Hitchins MP, Federman N. PMID: 37053536; PMCID: PMC10309547.
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Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors. N Engl J Med. 2023 03 09; 388(10):898-912. Gounder M, Ratan R, Alcindor T, Schöffski P, van der Graaf WT, Wilky BA, Riedel RF, Lim A, Smith LM, Moody S, Attia S, Chawla S, D'Amato G, Federman N, Merriam P, Van Tine BA, Vincenzi B, Benson C, Bui NQ, Chugh R, Tinoco G, Charlson J, Dileo P, Hartner L, Lapeire L, Mazzeo F, Palmerini E, Reichardt P, Stacchiotti S, Bailey HH, Burgess MA, Cote GM, Davis LE, Deshpande H, Gelderblom H, Grignani G, Loggers E, Philip T, Pressey JG, Kummar S, Kasper B. PMID: 36884323; PMCID: PMC11225596.
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SAINT: A Phase I/Expanded Phase II Study Using Safe Amounts of Ipilimumab, Nivolumab and Trabectedin as First-Line Treatment of Advanced Soft Tissue Sarcoma. Cancers (Basel). 2023 Jan 31; 15(3). Gordon EM, Chawla SP, Tellez WA, Younesi E, Thomas S, Chua-Alcala VS, Chomoyan H, Valencia C, Brigham DA, Moradkhani A, Quon D, Srikureja A, Wong SG, Tseng W, Federman N. PMID: 36765863; PMCID: PMC9913367.
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Maternal anemia and the risk of childhood cancer: A population-based cohort study in Taiwan. Pediatr Blood Cancer. 2023 03; 70(3):e30188. Orimoloye HT, Qureshi N, Lee PC, Wu CK, Saechao C, Federman N, Li CY, Ritz B, Arah OA, Heck JE. PMID: 36600459; PMCID: PMC10773261.
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Maternal anemia and childhood cancer: a population-based case-control study in Denmark. Cancer Epidemiol. 2023 02; 82:102308. Qureshi N, Orimoloye H, Hansen J, Saechao C, Olsen J, Federman N, Huang X, He D, Ritz B, Heck JE. PMID: 36434977; PMCID: PMC9904448.
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REsCue trial: Randomized controlled clinical trial with extended-release calcifediol in symptomatic COVID-19 outpatients. Nutrition. 2023 03; 107:111899. Bishop CW, Ashfaq A, Melnick JZ, Vazquez-Escarpanter E, Fialkow JA, Strugnell SA, Choe J, Kalantar-Zadeh K, Federman NC, Ng D, Adams JS. PMID: 36529089; PMCID: PMC9639413.
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Maternal diabetes and childhood cancer risks in offspring: two population-based studies. Br J Cancer. 2022 11; 127(10):1837-1842. Huang X, Hansen J, Lee PC, Wu CK, Federman N, Arah OA, Li CY, Olsen J, Ritz B, Heck JE. PMID: 36088507; PMCID: PMC9643384.
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Molecular pathogenesis of desmoid tumor and the role of γ-secretase inhibition. NPJ Precis Oncol. 2022 Sep 06; 6(1):62. Federman N. PMID: 36068332; PMCID: PMC9448813.
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IgM Warm Autoantibodies Causing Autoimmune Hemolytic Anemia in a Pediatric Patient. Lab Med. 2022 Jul 04; 53(4):e83-e86. Fortes P, Baez J, McGonigle AM, Ziman A, Federman N, Ward DC. PMID: 34865065.
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Cohort study of familial viral hepatitis and risks of paediatric cancers. Int J Epidemiol. 2022 05 09; 51(2):448-457. Heck JE, Wu CK, Huang X, Chew KW, Tong M, Federman N, Ritz B, Arah OA, Li CY, Yu F, Olsen J, Hansen J, Lee PC. PMID: 34966942; PMCID: PMC9308392.
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Polyendocrine Autoimmunity and Diabetic Ketoacidosis Following Anti-PD-1 and Interferon α. Pediatrics. 2022 04 01; 149(4). Dasgupta A, Tsay E, Federman N, Lechner MG, Su MA. PMID: 35274131; PMCID: PMC9804498.
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Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations. Adv Sci (Weinh). 2022 05; 9(14):e2105853. Sun N, Tran BV, Peng Z, Wang J, Zhang C, Yang P, Zhang TX, Widjaja J, Zhang RY, Xia W, Keir A, She JW, Yu HH, Shyue JJ, Zhu H, Agopian VG, Pei R, Tomlinson JS, Toretsky JA, Jonas SJ, Federman N, Lu S, Tseng HR, Zhu Y. PMID: 35486030; PMCID: PMC9108594.
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Personalized chordoma organoids for drug discovery studies. Sci Adv. 2022 02 18; 8(7):eabl3674. Al Shihabi A, Davarifar A, Nguyen HTL, Tavanaie N, Nelson SD, Yanagawa J, Federman N, Bernthal N, Hornicek F, Soragni A. PMID: 35171675; PMCID: PMC8849332.
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Comparative effectiveness of larotrectinib and entrectinib for TRK fusion cancer. Am J Manag Care. 2022 01; 28(2 Suppl):S26-S32. Carlson JJ, Italiano A, Brose MS, Federman N, Lassen U, Kummar S, Sullivan SD. PMID: 35201681; PMCID: PMC11446158.
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Diagnosis and management of TRK fusion cancer. Am J Manag Care. 2022 01; 28(2 Suppl):S15-S25. Kummar S, Italiano A, Brose MS, Carlson JJ, Sullivan SD, Lassen U, Federman N. PMID: 35201680; PMCID: PMC10949933.
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T-LAK cell-originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma. Mol Oncol. 2021 12; 15(12):3721-3737. Thanindratarn P, Wei R, Dean DC, Singh A, Federman N, Nelson SD, Hornicek FJ, Duan Z. PMID: 34115928; PMCID: PMC8637563.
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The Role of Social Media in Providing Support from Friends for Adolescent and Young Adult (AYA) Patients and Survivors of Sarcoma: Perspectives of AYA, Parents, and Providers. J Adolesc Young Adult Oncol. 2021 12; 10(6):720-725. Donovan E, Martin SR, Seidman LC, Zeltzer LK, Cousineau TM, Payne LA, Knoll M, Weiman M, Federman NC. PMID: 33844938; PMCID: PMC8742252.
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What's New in Pediatric Orthopaedic Tumor Surgery. J Pediatr Orthop. 2021 Feb 01; 41(2):e174-e180. Williams AK, Crawford B, Federman NC, Bernthal N, Arkader A. PMID: 33027233.
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Primary Renal Ewing Sarcoma in Children and Young Adults. J Pediatr Hematol Oncol. 2020 11; 42(8):474-481. Bradford K, Nobori A, Johnson B, Allen-Rhoades W, Naik-Mathuria B, Panosyan EH, Gotesman M, Lasky J, Cheng J, Ikeda A, Goldstein J, Singh A, Federman N. PMID: 32282650; PMCID: PMC7554078.
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[18F]FDG PET/CT for evaluating early response to neoadjuvant chemotherapy in pediatric patients with sarcoma: a prospective single-center trial. EJNMMI Res. 2020 Oct 15; 10(1):122. Polverari G, Ceci F, Passera R, Crane J, Du L, Li G, Fanti S, Bernthal N, Eilber FC, Allen-Auerbach M, Czernin J, Calais J, Federman N. PMID: 33063147; PMCID: PMC7561652.
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Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies. Adv Funct Mater. 2020 Dec 01; 30(49). Dong J, Zhang RY, Sun N, Hu J, Smalley MD, Zhou A, Yue H, Rothermich W, Chen M, Chen J, Ye J, Teng PC, Qi D, Toretsky JA, Tomlinson JS, Li M, Weiss PS, Jonas SJ, Federman N, Wu L, Zhao M, Tseng HR, Zhu Y. PMID: 34220409; PMCID: PMC8248519.
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Spina bifida and pediatric cancers. Pediatr Hematol Oncol. 2020 Oct; 37(7):630-636. Heck JE, Lee PC, Wu CK, Li CY, He D, Federman N, Yu F, Olsen J, Ritz B, Arah OA, Hansen J. PMID: 32364426; PMCID: PMC7577564.
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Results of a Randomized, Double-Blinded, Placebo-Controlled, Phase 2.5 Study of Saracatinib (AZD0530), in Patients with Recurrent Osteosarcoma Localized to the Lung. Sarcoma. 2020; 2020:7935475. Baird K, Glod J, Steinberg SM, Reinke D, Pressey JG, Mascarenhas L, Federman N, Marina N, Chawla S, Lagmay JP, Goldberg J, Milhem M, Loeb DM, Butrynski JE, Turpin B, Staddon A, Spunt SL, Jones RL, Rodler ET, Schuetze SM, Okuno SH, Helman L. PMID: 32398945; PMCID: PMC7211262.
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Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials. Lancet Oncol. 2020 04; 21(4):531-540. Hong DS, DuBois SG, Kummar S, Farago AF, Albert CM, Rohrberg KS, van Tilburg CM, Nagasubramanian R, Berlin JD, Federman N, Mascarenhas L, Geoerger B, Dowlati A, Pappo AS, Bielack S, Doz F, McDermott R, Patel JD, Schilder RJ, Tahara M, Pfister SM, Witt O, Ladanyi M, Rudzinski ER, Nanda S, Childs BH, Laetsch TW, Hyman DM, Drilon A. PMID: 32105622; PMCID: PMC7497841.
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A Case of a 15-Month-Old With Periorbital Edema and Severe Anemia. Pediatrics. 2020 03; 145(3). Kamzan AD, Newcomer CA, Wozniak LJ, Federman NC, Kim LS. PMID: 32079720; PMCID: PMC11446159.
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Clinical and molecular characterization of primary sclerosing epithelioid fibrosarcoma of bone and review of the literature. Genes Chromosomes Cancer. 2020 04; 59(4):217-224. Tsuda Y, Dickson BC, Dry SM, Federman N, Suurmeijer AJH, Swanson D, Sung YS, Zhang L, Healey JH, Antonescu CR. PMID: 31675134; PMCID: PMC7082133.
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A Phase 2, International, Multicenter, Open-label Clinical Trial of Subcutaneous Tbo-Filgrastim in Pediatric Patients With Solid Tumors Undergoing Myelosuppressive Chemotherapy. J Pediatr Hematol Oncol. 2019 10; 41(7):525-531. Federman N, Dragomir MD, Kizyma Z, Roganovic J, Bias P, Lammerich A, Ben Arie ZR, Zou L, Hoehn G, Buchner A. PMID: 31274668.
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Larotrectinib, a highly selective tropomyosin receptor kinase (TRK) inhibitor for the treatment of TRK fusion cancer. Expert Rev Clin Pharmacol. 2019 Oct; 12(10):931-939. Federman N, McDermott R. PMID: 31469968.
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Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. JBMR Plus. 2019 Oct; 3(10):e10210. Upfill-Brown A, Bukata S, Bernthal NM, Felsenfeld AL, Nelson SD, Singh A, Wesseling-Perry K, Eilber FC, Federman NC. PMID: 31687646; PMCID: PMC6820455.
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Is polycystic kidney disease associated with malignancy in children? Mol Genet Genomic Med. 2019 07; 7(7):e00725. Friend BD, Wolfe Schneider K, Garrington T, Truscott L, Martinez-Agosto JA, Venick RS, Tsai Chambers E, Weng P, Farmer DG, Chang VY, Federman N. PMID: 31197971; PMCID: PMC6625336.
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Pathologic Response to Neoadjuvant Therapy is Associated With Improved Long-term Survival in High-risk Primary Localized Malignant Peripheral Nerve Sheath Tumors. Am J Clin Oncol. 2019 05; 42(5):426-431. Shurell-Linehan E, DiPardo BJ, Elliott IA, Graham DS, Eckardt MA, Dry SM, Nelson SD, Singh AS, Kalbasi A, Federman N, Bernthal NM, Eilber FC. PMID: 30913092.
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A Mobile-Based Mindfulness and Social Support Program for Adolescents and Young Adults With Sarcoma: Development and Pilot Testing. JMIR Mhealth Uhealth. 2019 03 18; 7(3):e10921. Donovan E, Martin SR, Seidman LC, Zeltzer LK, Cousineau TM, Payne LA, Trant M, Weiman M, Knoll M, Federman NC. PMID: 30882352; PMCID: PMC6441858.
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TRK Fusion Cancers in Children: A Clinical Review and Recommendations for Screening. J Clin Oncol. 2019 02 20; 37(6):513-524. Albert CM, Davis JL, Federman N, Casanova M, Laetsch TW. PMID: 30592640.
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Long-term Outcomes With Ifosfamide-based Hypofractionated Preoperative Chemoradiotherapy for Extremity Soft Tissue Sarcomas. Am J Clin Oncol. 2018 12; 41(12):1154-1161. Pennington JD, Eilber FC, Eilber FR, Singh AS, Reed JP, Chmielowski B, Eckardt JJ, Bukata SV, Bernthal NM, Federman N, Nelson SD, Dry SM, Wang PC, Luu M, Selch MT, Steinberg ML, Kalbasi A, Kamrava M. PMID: 29664796.
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Fetal programming and Wilms tumor. Pediatr Blood Cancer. 2019 01; 66(1):e27461. Heck JE, He D, Janzen C, Federman N, Olsen J, Ritz B, Hansen J. PMID: 30255546; PMCID: PMC6530460.
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The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas. Cancer. 2018 11 01; 124(21):4241-4247. DuBois SG, Laetsch TW, Federman N, Turpin BK, Albert CM, Nagasubramanian R, Anderson ME, Davis JL, Qamoos HE, Reynolds ME, Cruickshank S, Cox MC, Hawkins DS, Mascarenhas L, Pappo AS. PMID: 30204247; PMCID: PMC6263791.
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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 2018 05 14; 33(5):905-921.e5. Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 29763624; PMCID: PMC6451645.
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Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study. Lancet Oncol. 2018 05; 19(5):705-714. Laetsch TW, DuBois SG, Mascarenhas L, Turpin B, Federman N, Albert CM, Nagasubramanian R, Davis JL, Rudzinski E, Feraco AM, Tuch BB, Ebata KT, Reynolds M, Smith S, Cruickshank S, Cox MC, Pappo AS, Hawkins DS. PMID: 29606586; PMCID: PMC5949072.
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Is Core Needle Biopsy Reliable in Differentiating Between Aggressive Benign and Malignant Radiolucent Bone Tumors? Clin Orthop Relat Res. 2018 03; 476(3):568-577. Hegde V, Burke ZDC, Park HY, Zoller SD, Johansen D, Kelley BV, Levine B, Motamedi K, Federman NC, Seeger LL, Nelson SD, Bernthal NM. PMID: 29529643; PMCID: PMC6260019.
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Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. N Engl J Med. 2018 02 22; 378(8):731-739. Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM. PMID: 29466156; PMCID: PMC5857389.
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Alveolar soft part sarcoma in children and young adults: A report of 69 cases. Pediatr Blood Cancer. 2018 05; 65(5):e26953. Flores RJ, Harrison DJ, Federman NC, Furman WL, Huh WW, Broaddus EG, Okcu MF, Venkatramani R. PMID: 29350467.
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Clinical Factors That Affect the Establishment of Soft Tissue Sarcoma Patient-Derived Orthotopic Xenografts: A University of California, Los Angeles, Sarcoma Program Prospective Clinical Trial. JCO Precis Oncol. 2017; 2017. Russell TA, Eckardt MA, Murakami T, Elliott IA, Kawaguchi K, Kiyuna T, Igarashi K, Li Y, Crompton JG, Graham DS, Dry SM, Bernthal N, Yanagawa J, Kalbasi A, Federman N, Chmielowski B, Singh AS, Hoffman RM, Eilber FC. PMID: 30613825; PMCID: PMC6319895.
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Fatal orthotopic liver transplant organ rejection induced by a checkpoint inhibitor in two patients with refractory, metastatic hepatocellular carcinoma. Pediatr Blood Cancer. 2017 Dec; 64(12). Friend BD, Venick RS, McDiarmid SV, Zhou X, Naini B, Wang H, Farmer DG, Busuttil RW, Federman N. PMID: 28643391.
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Rexin-G®, a tumor-targeted retrovector for malignant peripheral nerve sheath tumor: A case report. Mol Clin Oncol. 2017 Jun; 6(6):861-865. Kim S, Federman N, Gordon EM, Hall FL, Chawla SP. PMID: 28588778; PMCID: PMC5451875.
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Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug. Oncotarget. 2017 Jan 31; 8(5):8035-8042. Murakami T, Igarashi K, Kawaguchi K, Kiyuna T, Zhang Y, Zhao M, Hiroshima Y, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell T, Federman N, Singh A, Elliott I, Matsuyama R, Chishima T, Tanaka K, Endo I, Eilber FC, Hoffman RM. PMID: 28030831; PMCID: PMC5352380.
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Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma. Cancer Immunol Res. 2017 02; 5(2):118-126. Nowicki TS, Akiyama R, Huang RR, Shintaku IP, Wang X, Tumeh PC, Singh A, Chmielowski B, Denny C, Federman N, Ribas A. PMID: 28039162; PMCID: PMC5290092.
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Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016 Dec; 9(4):435-444. Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD, Federman N, Bernthal NM. PMID: 27778155; PMCID: PMC5127951.
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Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. Oncotarget. 2016 Sep 27; 7(39):64300-64308. Shurell E, Singh AS, Crompton JG, Jensen S, Li Y, Dry S, Nelson S, Chmielowski B, Bernthal N, Federman N, Tumeh P, Eilber FC. PMID: 27588404; PMCID: PMC5325443.
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Novel association of familial testicular germ cell tumor and autosomal dominant polycystic kidney disease with PKD1 mutation. Pediatr Blood Cancer. 2017 01; 64(1):100-102. Truscott L, Gell J, Chang VY, Lee H, Strom SP, Pillai R, Sisk A, Martinez-Agosto JA, Anderson M, Federman N. PMID: 27577987; PMCID: PMC5937546.
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Sclerostin expression in skeletal sarcomas. Hum Pathol. 2016 12; 58:24-34. Shen J, Meyers CA, Shrestha S, Singh A, LaChaud G, Nguyen V, Asatrian G, Federman N, Bernthal N, Eilber FC, Dry SM, Ting K, Soo C, James AW. PMID: 27498059; PMCID: PMC6560186.
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Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2016 Jul 26; 7(30):47556-47564. Murakami T, Singh AS, Kiyuna T, Dry SM, Li Y, James AW, Igarashi K, Kawaguchi K, DeLong JC, Zhang Y, Hiroshima Y, Russell T, Eckardt MA, Yanagawa J, Federman N, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. PMID: 27286459; PMCID: PMC5216960.
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Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening. J Cell Biochem. 2017 02; 118(2):361-365. Kiyuna T, Murakami T, Tome Y, Igarashi K, Kawaguchi K, Russell T, Eckardt MA, Crompton J, Singh A, Bernthal N, Bukata S, Federman N, Kanaya F, Eilber FC, Hoffman RM. PMID: 27357060.
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Prospective immunotherapies in childhood sarcomas: PD1/PDL1 blockade in combination with tumor vaccines. Pediatr Res. 2016 Mar; 79(3):371-7. Nowicki TS, Anderson JL, Federman N. PMID: 26595537.
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Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas. PLoS One. 2015; 10(9):e0133610. Anderson JL, Park A, Akiyama R, Tap WD, Denny CT, Federman N. PMID: 26402468; PMCID: PMC4581723.
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Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients. BMC Cancer. 2014 Nov 15; 14:827. Shurell E, Tran LM, Nakashima J, Smith KB, Tam BM, Li Y, Dry SM, Federman N, Tap WD, Wu H, Eilber FC. PMID: 25398666; PMCID: PMC4237782.
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Risk stratification of patients undergoing pulmonary metastasectomy for soft tissue and bone sarcomas. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):85-92. Lin AY, Kotova S, Yanagawa J, Elbuluk O, Wang G, Kar N, Elashoff D, Grogan T, Cameron RB, Singh A, Chmielowski B, Federman N, Nelson SD, Lee P, Eilber FC, Lee JM. PMID: 25312228.
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Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children. J Pediatr Hematol Oncol. 2014 Jul; 36(5):337-41. Mitton B, Seeger LL, Eckardt MA, Motamedi K, Eilber FC, Nelson SD, Eckardt JJ, Federman N. PMID: 23588331.
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Giant cell tumor of bone in childhood: clinical aspects and novel therapeutic targets. Paediatr Drugs. 2014 Feb; 16(1):21-8. Federman N, Brien EW, Narasimhan V, Dry SM, Sodhi M, Chawla SP. PMID: 24114694.
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Congenital Extrarenal Extra-Central Nervous System Malignant Rhabdoid Tumor of the Upper Extremity: A Case Report. JBJS Case Connect. 2013 Dec 11; 3(4 Suppl 6):e124. Frank JM, Eckardt JJ, Nelson SD, Seeger L, Federman N. PMID: 29252280.
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A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): success of combined therapy and the use of orthotopic liver transplant. J Pediatr Hematol Oncol. 2013 Aug; 35(6):451-5. Plant AS, Busuttil RW, Rana A, Nelson SD, Auerbach M, Federman NC. PMID: 23138115.
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An engineered anti-CA19-9 cys-diabody for positron emission tomography imaging of pancreatic cancer and targeting of polymerized liposomal nanoparticles. J Surg Res. 2013 Nov; 185(1):45-55. Girgis MD, Federman N, Rochefort MM, McCabe KE, Wu AM, Nagy JO, Denny C, Tomlinson JS. PMID: 23827791.
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A child with gemcitabine-induced severe radiation recall myositis resulting in a compartment syndrome. J Pediatr Hematol Oncol. 2013 Mar; 35(2):156-61. Eckardt MA, Bean A, Selch MT, Federman N. PMID: 23274380.
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Whole exome sequencing of pediatric gastric adenocarcinoma reveals an atypical presentation of Li-Fraumeni syndrome. Pediatr Blood Cancer. 2013 Apr; 60(4):570-4. Chang VY, Federman N, Martinez-Agosto J, Tatishchev SF, Nelson SF. PMID: 23015295; PMCID: PMC4170733.
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Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma. 2012; 2012:126906. Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT. PMID: 23024593; PMCID: PMC3447386.
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Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas. Expert Rev Anticancer Ther. 2012 Sep; 12(9):1217-28. Chmielowski B, Federman N, Tap WD. PMID: 23098121.
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Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities. Pediatr Res. 2012 Aug; 72(2):112-21. Anderson JL, Denny CT, Tap WD, Federman N. PMID: 22546864; PMCID: PMC4283808.
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Long-term results (>25 years) of a randomized, prospective clinical trial evaluating chemotherapy in patients with high-grade, operable osteosarcoma. Cancer. 2012 Dec 01; 118(23):5888-93. Bernthal NM, Federman N, Eilber FR, Nelson SD, Eckardt JJ, Eilber FC, Tap WD. PMID: 22648705.
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Alveolar soft part sarcomas: molecular pathogenesis and implications for novel targeted therapies. Sarcoma. 2012; 2012:428789. Mitton B, Federman N. PMID: 22566752; PMCID: PMC3337503.
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Is there a need for dedicated bone imaging in addition to 18F-FDG PET/CT imaging in pediatric sarcoma patients? J Pediatr Hematol Oncol. 2012 Mar; 34(2):131-6. Walter F, Czernin J, Hall T, Allen-Auerbach M, Walter MA, Dunkelmann S, Federman N. PMID: 22134608.
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Coexistence of translocation(1,19) and the Philadelphia chromosome in a child's first presentation of chronic myeloid leukemia in blast crisis treated with dasatinib. Pediatr Hematol Oncol. 2011 Nov; 28(8):669-75. Eckardt MA, Chang VY, Rao NP, Federman N. PMID: 22023462.
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18F-fluorodeoxyglucose uptake of bone and soft tissue sarcomas in pediatric patients. Pediatr Hematol Oncol. 2011 Oct; 28(7):579-87. Walter F, Federman N, Apichairuk W, Nelson S, Phelps ME, Allen-Auerbach M, Walter MA, Czernin J. PMID: 21936620.
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Extramedullary acute myelocytic leukemia following liver transplantation for VOD with immunodeficiency. J Pediatr Gastroenterol Nutr. 2011 Sep; 53(3):346-9. Wozniak LJ, Yang HM, Lassman CR, Federman N, Wu SS. PMID: 21865981.
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Not all hemangiomas are benign--epithelioid hemangioendothelioma: an aggressive vascular lesion in children. Pediatr Hematol Oncol. 2011 Oct; 28(7):622-4. Eckardt MA, Chang VY, Nelson SD, Federman N. PMID: 21787124.
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Targeting liposomes toward novel pediatric anticancer therapeutics. Pediatr Res. 2010 May; 67(5):514-9. Federman N, Denny CT. PMID: 20118828.
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ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways. Mol Cancer Ther. 2010 Mar; 9(3):653-60. Ikeda AK, Judelson DR, Federman N, Glaser KB, Landaw EM, Denny CT, Sakamoto KM. PMID: 20197394; PMCID: PMC2837519.
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Estimated cumulative radiation dose from PET/CT in children with malignancies: a 5-year retrospective review. Pediatr Radiol. 2010 May; 40(5):681-6. Chawla SC, Federman N, Zhang D, Nagata K, Nuthakki S, McNitt-Gray M, Boechat MI. PMID: 19967534; PMCID: PMC2847163.
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The multidisciplinary management of osteosarcoma. Curr Treat Options Oncol. 2009 Apr; 10(1-2):82-93. Federman N, Bernthal N, Eilber FC, Tap WD. PMID: 19238553.
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PET/CT in evaluating pediatric malignancies: a clinician's perspective. J Nucl Med. 2007 Dec; 48(12):1920-2. Federman N, Feig SA. PMID: 18056331.
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Targeted therapies for soft-tissue sarcomas. Expert Rev Anticancer Ther. 2007 May; 7(5):725-33. Tap WD, Federman N, Eilber FC. PMID: 17492935.
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The genetic basis of bone marrow failure syndromes in children. Mol Genet Metab. 2005 Sep-Oct; 86(1-2):100-9. Federman N, Sakamoto KM. PMID: 16125992.
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Topics in pediatric leukemia--Fanconi's anemia: new insights. MedGenMed. 2005 Apr 06; 7(2):23. Federman N, Sakamoto KM. PMID: 16369402; PMCID: PMC1681561.
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Bilateral microtia and cleft palate in cousins with Diamond-Blackfan anemia. Am J Med Genet. 2001 Jul 01; 101(3):268-74. Gripp KW, McDonald-McGinn DM, La Rossa D, McGain D, Federman N, Vlachos A, Glader BE, McKenzie SE, Lipton JM, Zackai EH. PMID: 11424144.
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Hematopoietic stem cell transplantation for Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry. Bone Marrow Transplant. 2001 Feb; 27(4):381-6. Vlachos A, Federman N, Reyes-Haley C, Abramson J, Lipton JM. PMID: 11313667.
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Osteogenic sarcoma associated with Diamond-Blackfan anemia: a report from the Diamond-Blackfan Anemia Registry. J Pediatr Hematol Oncol. 2001 Jan; 23(1):39-44. Lipton JM, Federman N, Khabbaze Y, Schwartz CL, Hilliard LM, Clark JI, Vlachos A, Diamond-Black Anemia Registry. PMID: 11196268.
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