Abstract Human IgG has only one conserved glycosylation site located in the Cγ2 domain of the Fc region that accounts for the presence of two sugar moieties per IgG. These IgG sugar cores play a critical role in a number of IgG effector functions. In the present review, we descri…
medRxiv preprint doi: https://doi.org/10.1101/2021.06.02.21257975; this version posted August 10, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. I…
UC Irvine UC Irvine Previously Published Works Title The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization Permalink https://escholarship.org/uc/item/5gp9w0q3 Journal mSphere, 7(4) ISSN 1556-6811 Authors Ka…
Research Article Free access | 10.1172/JCI57834 Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies 1 Department of Immunology and Microbiology, Stanford University School of Medicine, Sta…
Abstract Studies are needed to evaluate the safety and effectiveness of mRNA SARS-CoV-2 vaccination during pregnancy, and the levels of protection provided to their newborns through placental transfer of antibodies. Here, we evaluate the transplacental transfer of mRNA vaccine pr…
Frontiers | The Effects of COVID-19 Vaccination on Lactating Women: A Systematic Review of the Literature SYSTEMATIC REVIEW article Front. Immunol. , 08 April 2022 Sec. Nutritional Immunology Volume 13 - 2022 | https://doi.org/10.3389/fimmu.2022.852928 The Effects of COVID-19 Vac…
Frontiers | The Effects of COVID-19 Vaccination on Lactating Women: A Systematic Review of the Literature SYSTEMATIC REVIEW article Front. Immunol. , 08 April 2022 Sec. Nutritional Immunology Volume 13 - 2022 | https://doi.org/10.3389/fimmu.2022.852928 The Effects of COVID-19 Vac…
The breadth and magnitude of P. falciparum -specific IgM and IgG responses are greater in the malaria-resistant Fulani versus the malaria-susceptible Dogon, and P. falciparum -specific IgM responses more strongly distinguish the two ethnic groups. Keywords: antibodies, Dogon, Ful…
Frontiers | Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity MINI REVIEW article Front. Immunol. , 12 July 2022 Sec. Nutritional Immunology Volume 13 - 2022 | https://doi.org/10.3389/fi…
Abstract Exposure to Plasmodium falciparum is associated with circulating “atypical” memory B cells (atMBCs), which appear similar to dysfunctional B cells found in HIV-infected individuals. Functional analysis of atMBCs has been limited, with one report suggesting these cells ar…
Journal Pre-proof Clinical and Therapeutic Predictors of Disease Outcomes in AQP4-IgG+ Neuromyelitis Optica Spectrum Disorder Amy Kunchok MBBS, CORe , Charles Malpas PhD, CORe , Petra Nytrova PhD , Eva Kubala Havrdova PhD , Raed Alroughani MD , Murat Terzi MD , Bassem Yamout MD ,…
Abstract To optimize malaria control, WHO has prioritised the need for new indicators to evaluate the efficacy of malaria vector control strategies. The gSG6-P1 peptide from gSG6 protein of Anopheles gambiae salivary glands was previously designed as a specific salivary sequence …
Abstract In human immunodeficiency virus (HIV)–infected individuals, higher levels of anti-cytomegalovirus (CMV) immunoglobulin G (IgG) antibody have been associated with increased immune activation, increased HIV transmission, cardiovascular complications, and neurocognitive imp…
Frontiers | Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination ORIGINAL RESEARCH article Front. Immunol. , 15 March 2019 Sec. Microbial Immunology Volume 10 - 2019 | https://doi.org/10.3389/fim…
Abstract Standard entomological methods for evaluating the impact of vector control lack sensitivity in low-malaria-risk areas. The detection of human IgG specific to Anopheles gSG6-P1 salivary antigen reflects a direct measure of human–vector contact. This study aimed to assess …