In the last several years, deep-sequencing has been fueling new and unexpected discoveries in the field of ncRNAs. These discoveries have been leading us away from the linear view of the “Central Dogma of Biology” and towards a framework in which ncRNAs are as important as protei…

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A comprehensive repertoire of tRNA-derived fragments in prostate cancer - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or https:// means you've saf…

Prostate cancer (PCa) is the most common cancer among men in developed countries. Although its genetic background is thoroughly investigated, rather little is known about the role of small non-coding RNAs (sncRNA) in this disease. tRNA-derived fragments (tRFs) represent a new cla…

bioRxiv preprint doi: https://doi.org/10.1101/2022.10.11.511716; this version posted October 14, 2022. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It…

INTRODUCTION A major characteristic of the last decade is the explosion in the amount of genomic, transcriptomic, epigenomic, and other “–omic” data that can be generated for a given individual, healthy or patient. Not surprisingly, the ensuing data tsunami enabled invaluable int…

Identification of six types of genomic regions based on TRF binding data We selected five ENCODE cell lines that have the largest numbers of TRFs with binding sites assayed by ChIP-seq (Table S1 in Additional file 1 ). In total, 117 TRFs are included in the ENCODE datasets from t…

Abstract Huntington’s Disease (HD) is a neurodegenerative disorder caused by an autosomal-dominant mutation in the huntingtin gene, which manifests with a triad of motor, cognitive and psychiatric declines. Individuals with HD often present with disturbed sleep/wake cycles, but i…

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or…

Patients, samples, and sequencing limitations 526 samples were obtained from 472 patient donors. The patients span a range of ages and several races (Table 1 ). These samples form evenly sized subgroups from the standpoint of Gleason score at initial diagnosis (Table 1 ). It is i…

1. Introduction Cellular RNAs are traditionally divided into three ubiquitous classes: mRNAs possessing protein-coding function, whose sequence is decoded to produce proteins, ribosomal (r) RNAs possessing enzymatic activities required for protein synthesis, and tRNAs that delive…

bioRxiv preprint doi: https://doi.org/10.1101/2022.11.01.512632; this version posted November 1, 2022. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It…

Acoust. Sci. & Tech. 41, 1 (2020) #2020 The Acoustical Society of Japan Musical expertise enhances the cortical tracking of the acoustic envelope during naturalistic music listening Giovanni M. Di Liberto1; , Claire Pelofi2 , Shihab Shamma1;3 and Alain de Cheveigné1;4 1 Laboratoi…

ACTA COMPORTAMENTALIA Vol. 33, Núm. 2, pp. 329-350 Efeitos do Promove-Crianças no Repertório Infantil e nas Práticas Educativas Segundo Pais e Professores (Effects of Promove-Crianças on Children’s Repertoires and Educational Practices According to Parents and Teachers) Alessandr…

Log In Sign Up About Press Papers Terms Privacy Copyright We're Hiring! Help Center Claim details Research claim The Temporal Response Function (TRF) quantitatively estimates stimulus-response relationships, crucial for understanding neural tracking of continuous stimuli like spe…