Abstract MicroRNAs (miRNAs) are small noncoding RNAs that act as potent regulators of gene expression. The discovery of miRNAs with specific temporal and spatial expression patterns revealed a hidden layer of post-transcriptional gene regulation. Furthermore, differential express…
microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or https:// means yo…
cell biochemistry and function Cell Biochem Funct (2012) Published online in Wiley Online Library (wileyonlinelibrary.com) DOI: 10.1002/cbf.2847 Prostate cancer is known by the companionship with ATM and miRNA it keeps: craftsmen of translation have dual behaviour with tailors of…
Narrative Analysis of the Iyezidi Chirok of Mir Mih : The Iyezidi Epic of Immortality Narrative Analysis of the Iyezidi Chirok of Mir Mih : The Iyezidi Epic of Immortality Lazgin Kheder Barany Rania Qaso Department of English, Department of English , College of Languages, College…
Abstract Although it is well established that tumors initiate an angiogenic switch, the molecular basis of this process remains incompletely understood. Here we show that the miRNA miR-132 acts as an angiogenic switch by targeting p120RasGAP in the endothelium and thereby inducin…
Abstract Background The treatment options for hepatocellular carcinoma (HCC) are limited, and there is no effective drug that can improve long-term survival rates. Complicated cocktails consisting of multiple medications with toxicities are frequently used to treat cancer. The cu…
INTRODUCTION Malignant melanoma (MM), an aggressive skin malignancy, is the fifth most common malignant tumor in men and the seventh most common malignant tumor in women [ 1 , 2 ]. Recent studies showed that the incidence of MM has increased by 3.1% per year [ 3 ]. Despite signif…
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) o…
Significance This study highlights a pathogenic role for loss of miR-15/16 in chronic lymphocytic leukemia (CLL). We find that loss of mi R-15/16 promotes overexpression of BCL2 and ROR1 , which each factor in leukemia pathogenesis. Treatment with single-agent venetoclcax, which …
Introduction Since the first microRNA (miRNA) Lin-4 was discovered in nematode in 1993 1 , and the function of miRNA let-7 was subsequently demonstrated 2 , miRNAs began to attract the attention of researchers and subsequently they have become an intense and focused area of biolo…
Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) o…
Russian payment system Mir ( Russian : Мир , IPA: [ˈmʲir] ; lit. ' the world ' or ' peace ' ) is a Russian card payment system for electronic fund transfers established by the Central Bank of Russia under a law adopted on 1 May 2017. [ 1 ] It is operated by the Russian National C…
Abstract Radiation-induced cognitive dysfunction (RICD) is a progressive and debilitating health issue facing patients following cranial radiotherapy to control CNS cancers. There has been some success treating RICD in rodents using human neural stem cell (hNSC) transplantation, …
Abstract Background/Aim: Colorectal cancer (CRC) cells secrete inflammatory cytokines that affect CRC progression. The aim of the present study was to determine if micro-RNA-140(miR-140) regulates inflammatory cytokine secretion induced by lipopolysaccharide (LPS) in colorectal c…
Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3′-Untranslated Region Polymorphism C+87T by MicroRNA-107 - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organizatio…