Abstract miR-17 family microRNAs (miRNAs) are crucial for embryo development, however, their role in muscle development is still unclear. miR-20a-5p and miR-20b-5p belong to the miR-17 family and are transcribed from the miR-17~92 and miR-106a~363 clusters respectively. In this s…

JCI - MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy Go to JCI Insight About Editors Consulting Editors For authors Publication ethics Publication alerts by email Advertising Job board Contact The Journal of Clinical Investigation Current issue …

Abstract Skeletal muscle differentiation can be regulated by various transcription factors and non-coding RNAs. In our previous work, miR-223 is differentially expressed in the skeletal muscle of chicken with different growth rates, but its role, expression and action mechanism i…

Abstract Hepatitis C virus (HCV) depends on liver-specific microRNA miR-122 for efficient viral RNA amplification in liver cells. This microRNA interacts with two different conserved sites at the very 5’ end of the viral RNA, enhancing miR-122 stability and promoting replication …

Background MicroRNAs (miRNAs) are one category of small single-stranded non-coding RNA molecule (containing 20~25 nucleotides), which function in regulation of gene expression at the posttranscriptional level [ 1 , 2 ]. Generally, miRNAs could cause mRNAs degradation by binding t…

Europe PMC Funders Group Author Manuscript Nat Cell Biol. Author manuscript; available in PMC 2013 January 01. Published in final edited form as: Nat Cell Biol. ; 14(7): 659–665. doi:10.1038/ncb2521. Europe PMC Funders Author Manuscripts The H19 lincRNA is a developmental reservo…

[ 5 ] Erster Act. Erste Scene. Morgendämmerung. Wohnung des Sokrates. In der Nähe derselben das Haus des Strepsiades, in dessen Schlafgemach man hineinsieht. Strepsiades. Pheidippides. Einige Knechte im Hintergrunde. Alle liegen schlafend auf ihrem Nachtlager. Strepsiades. (erwac…

Tr a n s l a t i o n a l O n c o l o g y Volume 12 Number 1 January 2019 pp. 170–179 170 www.transonc.com MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells1 Sofia Aakko *, †, Anne Hege Straume ‡, §, Einar Elvbakken Birkela…

miR-23b-24-27b cluster in murine AAA We profiled miRNA expression in the porcine-pancreatic-elastase (PPE) infusion model in 10-week-old male C57BL/6J mice. The incidence, growth rate and size of aneurysmal expansion were measured by ultrasound (US) at 3, 7, 14, 21 and 28 days af…

Abstract Accumulating studies report that microRNAs (miRNAs) are actively involved in skeletal myogenesis. Previously, our study revealed that miR-146b-3p was related to the growth of skeletal muscle. Here, we further report that miR-146b-3p is essential for the proliferation, di…

Abstract Genome-wide association studies (GWAS) have identified chromosomal loci that affect risk of coronary heart disease (CHD) independent of classical risk factors. One such association signal has been identified at 6q23.2 in both Caucasians and East Asians. The lead CHD-asso…

Abstract MicroRNAs (miRNAs) are small noncoding RNAs that act as potent regulators of gene expression. The discovery of miRNAs with specific temporal and spatial expression patterns revealed a hidden layer of post-transcriptional gene regulation. Furthermore, differential express…

cell biochemistry and function Cell Biochem Funct (2012) Published online in Wiley Online Library (wileyonlinelibrary.com) DOI: 10.1002/cbf.2847 Prostate cancer is known by the companionship with ATM and miRNA it keeps: craftsmen of translation have dual behaviour with tailors of…

Narrative Analysis of the Iyezidi Chirok of Mir Mih : The Iyezidi Epic of Immortality Narrative Analysis of the Iyezidi Chirok of Mir Mih : The Iyezidi Epic of Immortality Lazgin Kheder Barany Rania Qaso Department of English, Department of English , College of Languages, College…

Abstract Although it is well established that tumors initiate an angiogenic switch, the molecular basis of this process remains incompletely understood. Here we show that the miRNA miR-132 acts as an angiogenic switch by targeting p120RasGAP in the endothelium and thereby inducin…